氯化血红素/热解石墨电极对单加酶的模拟——Ⅰ.电极表面氯化血红素的表征

氯化血红素(Ha)能较稳定地吸附在热解石墨电极表面上,该电极在0.5MH_2SO_4水溶液中循环伏安法研究表明,在100mV(vs.SCE)和-170mV(vs.SCE)附近有两对峰,分别指认为Ha的单体(monomer)吸附态和二聚体(dimer)吸附态。     

Synthesis and studies of organic nitrates of the heterofunctional series

N-Nicotinoyltris(hydroxymethy)aminomethane trinitrate hydronitrate, an analog ofN-nicotinoylethanolamine nitrate (the active principle of the antianginal drug nicorandil), was prepared byO-nitration of the corresponding triol with concentrated HNO₃. The structure of the reaction product was established by X-ray structural analysis. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2224–2227, December, 1997.     

Highly Sensitive Electrogenerated Chemiluminescence Detecting Ranitidine Based On Chemically Modifying Microenvironment of the Chemiluminescence Reaction

Using a graphite electrode modified with vaseline and NiO, ranitidine showed a strongly ECL enhancing effect for the weak ECL signal of electrooxidation of luminol. Based on this finding, a more sensitive ECL method for ranitidine was firstly proposed. Under the optimum experimental conditions, the ranitidine hydrochloride concentration in the range of 3.0×10^?8–9.0×10^?6 mol/L was proportional to the enhancing ECL signal and offered a 9×10^?9 mol/L detection limit for ranitidine hydrochloride. At the same time, based on the investigation on this ECL reaction mechanism, a new concept, to improve the suitable ECL reaction micro‐environment with chemically modified electrode technique for the better analytical performances of ECL analysis was also firstly proposed.     

An efficient and convenient KF/Al2O3 mediated synthesis of nitriles from aldehydes

KF/Al₂O₃ brings about a facile one-pot and economical conversion of various aryl and alkyl aldehydes into the corresponding nitriles in high yields by reaction with hydroxylamine hydrochloride.     

多孔碳球封装纳米碳化钼催化剂无溶剂催化苄胺偶联反应

以盐酸多巴胺，磷钼酸（PMo）为原料，通过离子交换和聚合作用形成一种有机-杂多酸杂化材料，在N₂条件下高温碳化制备出一种新型多孔碳球封装纳米碳化钼催化剂PDA-PMo-800.利用傅里叶变换红外（FT-IR），N₂吸脱附等温仪（BET），扫描电子显微镜（SEM），透射电子显微镜（TEM），X射线粉末衍射（XRD），拉曼光谱仪（Raman），热重分析仪（TG），能谱仪（EDS）对催化剂进行表征与分析.结果显示：催化剂PDA-PMo-800具有规整的花状球体形貌以及较高的比表面积（102 m²/g），纳米碳化钼颗粒（3~4 nm）均匀地分布在多孔碳球骨架内.在无溶剂以氧气为氧化剂的条件下，将该催化剂应用于苄胺的氧化偶联反应合成亚胺，实现较高的转化率及选择性，且催化剂可以多次重复使用并保持较高的催化活性.     

一种合成环己基-3-氟苄基酮的新方法

以环己碳酰氯、N，O-二甲基羟胺盐酸盐和3一氟苄基溴化镁为原料，经过酰化和缩合反应得到环己基-3-氟苄基酮．合成路线原料易得，操作简便，收率较高，各主要化合物结构经IR，MS和^1H-NMR确认．     

Rapid and simple determination of aldose reductase and sorbitol dehydrogenase

Rapid and well-reproducible methods were developed for the determination of aldose reductase and sorbitol dehydrogenase. The aldose reductase activity measurement is based on photometric o-toluidine aldose back-measurement, which is widely used in laboratories for the quantitative determination of glucose. The spectrophotometric method based on the quantitative decrease in NADH proved suitable for the measurement of sorbitol dehydrogenase activity.Both methods could well be employed for the measurement of the aldose reductase and sorbitol dehydrogenase activities of normal and diabetic tissue homogenizates, and for the comparison of the measured values.     

UiO-66/CoSO4复合材料对环境中盐酸左氧氟沙星的高效去除

以UiO-66为前驱体制得UiO-66/CoSO₄复合材料，借助扫描电子显微镜、透射电子显微镜、元素分析和比表面积分析等手段对复合材料的微观形貌和结构进行表征，采用吸附平衡实验，系统考察该复合材料的吸附性能.结果表明，在相同条件下UiO-66/CoSO₄复合材料比UiO-66对盐酸左氧氟沙星的去除率提高26.5%，且复合材料在30 min对盐酸左氧氟沙星的吸附达到平衡，最大吸附容量为108.4 mg·g^-1，其吸附特性符合假二级动力学模型.该UiO-66/CoSO₄复合材料制备过程简单，对实际环境水样和土样中盐酸左氧氟沙星的去除率在94.7%以上，且经过5次再生循环使用后，吸附效率无明显下降.     

盐酸芦氟沙星的荧光光谱分析法研究

研究了β-环糊精、表面活性剂、缓冲溶液及pH值、表面活性剂等对芦氟沙星荧光强度的影响。提出了用荧光光谱法测定芦氟沙星含量的新方法。该法操作简便，检出限低，用于实际样品分析，结果满意。     

ICP-AES法测定高温质子导体中的五种元素

研究用ICP-AES法测定高温质子导体中的钡、铈、锶、钇和镱，选定了适宜的溶解方法及分析条件，在溶解酸中加入盐酸羟胺，获得了较为满意的分析结果，相对标准差小于10%。