Silica microbeads capture fetal nucleated red blood cells for noninvasive prenatal testing of fetal ABO genotype

ABO hemolytic disease of the newborn (ABO-HDN), which may cause neonatal jaundice and polycythemia, or even stillbirth or neonatal death, is widespread in China. Prenatal testing for the fetal ABO blood group can reduce unnecessary concerns or ensure prompt treatment. Herein, we presented a method to employ high-density silica microbeads (SiO₂ MBs) for capturing fetal nucleated red blood cells (fnRBCs) in maternal peripheral blood, and we detected the ABO genotype of the fetus using these captured cells. We evaluated 52 patients using the SiO₂ MBs. Among 26 pregnant women with type O blood, 8 (30.8%) of the fetuses had type A blood, 5 (19.2%) had type B blood, and 13 (50%) had type O blood. SRY genes were detected in all 27 male fetuses. This study represents a simple and effective method for noninvasive prenatal detection of the fetal ABO genotype. We believe that this method has great potential for noninvasive prenatal testing of the fetal Rh blood group and other fetal diseases as well.     

Analytical and numerical studies for Seiches in a closed basin with bottom friction

A standing wave oscillation in a closed basin, known as a seiche, could cause destruction when its period matches the period of another wave generated by external forces such as wind, quakes, or abrupt changes in atmospheric pressure. It is due to the resonance phenomena that allow waves to have higher amplitude and greater energy, resulting in damages around the area. One condition that might restrict the resonance from occurring is when the bottom friction is present. Therefore, a modified mathematical model based on the shallow water equations will be used in this paper to investigate resonance phenomena in closed basins and to analyze the effects of bottom friction on the phenomena. The study will be conducted for several closed basin shapes. The model will be solved analytically and numerically in order to determine the natural resonant period of the basin, which is the period that can generate a resonance. The computational scheme proposed to solve the model is developed using the staggered grid finite volume method. The numerical scheme will be validated by comparing its results with the analytical solutions. As a result of the comparison, a rather excellent compatibility between the two results is achieved. Furthermore, the impacts that the friction coefficient has on the resonance phenomena are evaluated. It is observed that in the prevention of resonances, the bottom friction provides the best performance in the rectangular type while functioning the least efficient in the triangular basin. In addition, non-linearity effect as one of other factors that provide wave restriction is also considered and studied to compare its effect with the bottom friction effect on preventing resonance.     

氮化硼催化低碳烷烃氧化脱氢的活性起源探讨（英文）

页岩气的急速开采推动了以天然气替代石油的资源革命.除主组分甲烷外,天然气、页岩气中还包含大量乙烷、丙烷等低碳烷烃资源,将这些储量丰富的碳资源直接转化为烯烃等基础化学品有望革新以原油为基础的化学工业.现有烷烃催化脱氢制烯烃工艺中,直接脱氢过程吸热、热力学受限,且存在催化剂迅速失活的难题;而氧化脱氢是放热过程、无平衡限制,也无积碳等引发催化剂失活的问题,有利于提高反应效率、降低能耗,代表了更为高效和经济的新路线.但作为一个热力学爬坡过程,目前金属氧化物催化剂上烯烃产物很容易深度氧化到CO_2,选择性仍有待提高.非金属氮化硼能够有效活化低碳烷烃中的C-H键,促进烷烃氧化脱氢,并能够有效抑制深度氧化产物的生成,解决低碳烷烃临氧脱氢过程中产物易深度氧化的固有难题.本文综述了近期氮化硼在乙烷、丙烷、丁烷等低碳烷烃氧化脱氢制烯烃反应中的研究进展.以丙烷氧化脱氢为例,通过比较文献报道的几种氮化硼材料的氧化脱氢性能,发现羟基化氮化硼显示了最高的烯烃选择性和时空收率,以20.6%的丙烷转化率为基准,烯烃选择性超过90%,而时空收率可达6.8 golefin gcat~(-1) h~(-1).在此基础上,本文重点讨论了对于氮化硼材料催化活性起源的认识.主要实验事实和结论包括:氮化硼自身几乎没有氧化脱氢活性,而在烷烃氧化脱氢反应条件下存在活性诱导期;活性诱导期伴随着氮化硼边沿氧官能团化过程;氮化硼边沿B-O官能团没有脱氢活性,而B-OH官能团参与了氧化脱氢过程,辅助分子氧引发低碳烷烃脱氢反应;分子氧在羟基氮化硼边沿解离活化,反应过程中与边沿结构氧存在动态交换;氮化硼边沿羟基化定向合成过程可显著增强氧化脱氢反应活性.氮化硼作为一类新型烷烃氧化脱氢催化剂,目前正处于研究的初始阶段.因此,本文最后总结了一些关于氮化硼烷烃脱氢催化体系仍需深入研究的科学问题.     

Maximal degeneracy points of GKZ systems

Motivated by mirror symmetry, we study certain integral representations of solutions to the Gel´fand-Kapranov-Zelevinsky (GKZ) hypergeometric system. Some of these solutions arise as period integrals for Calabi-Yau manifolds in mirror symmetry. We prove that for a suitable compactification of the parameter space, there exist certain special boundary points, which we called maximal degeneracy points, at which all solutions but one become singular.

     

低体质量先天性心脏病患儿围术期的护理方法

目的分析围术期护理干预应用于低体质量先天性心脏病护理中的护理效果。方法研究对象为梅州市中医医院收治的64例低体质量先天性心脏病患儿,选择年份均为2014年1月至2016年1月期间,采用抽签的分组方式将其平均分为对照组和实验组,每32例患儿为1组,其中对照组患儿给予常规护理干预,而实验组的护理方式为围术期护理干预方法,将两组患儿的护理效果进行分析和对比。结果经过不同的护理干预,与对照组患儿相比,实验组患儿的家长护理满意度明显较高,差异对比P0.05,具有统计学意义。结论围术期护理干预应用于低体质量先天性心脏病护理中效果显著,值得应用推广。     

变采样周期和多包传输的非线性NCS故障检测

研究具有多包传输、时变采样周期和未知干扰输入的Lipschitz非线性网络控制系统的故障检测问题。利用主动变采样周期的方法将多包传输的非线性连续网络控制系统建模为离散切换系统,设计基于观测器的鲁棒故障检测滤波器构造残差产生系统,运用Lyapunov稳定性理论和线性矩阵不等式(LMI)技术,给出了使闭环系统渐近稳定的充分条件及故障检测滤波器的增益矩阵。最后运用仿真算例说明了故障检测滤波器的残差产生系统对故障具有敏感性,同时对外部扰动输入具有鲁棒性。     

光纤法-珀传感器监测混凝土固化期收缩应变的实验研究

本文介绍了光纤法-珀应变传感器的基本原理及优点,并用其进行了混凝土固化过程中的收缩应变监测实验,在混凝土两天的固化过程中监测到了130微应变的收缩应变.本文还对光纤法-珀应变传感器的温度稳定性能进行了理论分析及对比实验,实验结果表明,在一定条件下环境温度对光纤法-珀应变传感器的影响可忽略不计,因此可不用任何温度补偿.     

简谐振动实验中阻尼力作用的估算

根据振动振幅随时间的衰减来得到阻尼系数,并估算了阻尼力对振动周期和总机械能的影响。     

x~3振荡器及其周期

建立了ｘ~３振荡器模型,导出了它的振动周期公式．     

双周期裂纹场平面弹性焊接的数学问题

本文讨论双周期胞腔中含任意形状裂纹的不同材料的弹性平面焊接(焊线为任意形状的封闭光滑曲线)的第二基本问题.运用Мусхелишвили复变函数方法,对这类弹性平面问题建立起了数学模型,将求解弹性平衡问题化归为寻求复应力函数满足一定边界条件的边值问题,然后构造其解的形式,再将其转化为正则型的奇异积分方程,数学上严格证明其解的存在与唯一.