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A. V. Dhanunjaya Rao Rajendra Surasani B. P. Vykunteswararao T. Bhaskarkumar B. Srikanth Nivrutti R. Jogdand 《合成通讯》2016,46(18):1519-1528
An efficient and green approach has been developed for the synthesis of polyhydroquinoline derivatives via Hantzsch condensation reaction directly from corresponding substituted aromatic and aliphatic aldehydes, β-keto compounds, active methylene compounds, and ammonium chloride using recyclable polymer-supported sulfonic acid catalyst under aqueous conditions. Environmental acceptability, operational simplicity, low cost, excellent functional group compatibility, and high yields are the important features of this protocol. 相似文献