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A model for a finite memory effect in the Fisher equation had been presented by Cattaneo [Acad. Sci. 247 (1958) 431]. By this model the type of the governing equation is transformed from a parabolic type to a hyperbolic one. But the Cattaneo’s equation does not reduce to the logistic equation in the homogeneous regime. A new model is presented which conserves the parabolic generic equation as well as the reduction property. Memory effects are visualized in the two models through numerical computations of solutions. 相似文献
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近来,Lutwak,Yang和Zhang提出了新几何体Γ_(-p)K的概念,获得一些结论.本文引入混合新几何体Γ_(-p,i)K的概念,即新几何体是它的特殊类,得到了混合新几何体的一些性质,并建立了相关的不等式. 相似文献
136.
A new frog skin peptide, ranamargarin depicted as H-Asp-Asp-Ala-Ser-Asp-Arg-Ala-Lys-Lys-Phe-Tyr-Gly-Leu-Met-NH_(2′), was synthesized by the conventionalmethod. Comparisons of chemical and biological properties of both the synthetic and natural ranamargarins indicated that they were identical, so the chemical structure of ranamargarin was confirmed. Preliminary pharmacological study showed that ranamargarin was highly selective towards the SP-P subtype receptor. 相似文献
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Adnan Zahirović Marina Cindrić Sandra Kraljević Pavelić Mirsada Hukić Anja Harej 《Journal of Coordination Chemistry》2017,70(24):4030-4053
Heteroleptic ruthenium(II) bioflavonoid complexes of quercetin, morin, chrysin, and 3-hydroxyflavone were prepared and their interaction with CT DNA and BSA along with antioxidant and in vitro anticancer and antimicrobial activities was investigated. The formulation and characterization of complexes were achieved through elemental and thermal analysis, mass spectrometry, 1H NMR spectroscopy along with infrared, electronic absorption, and emission spectroscopy as well as square-wave voltammetry, and magnetic and conductivity measurements. Ruthenium(II) is octahedrally coordinated in cationic complex species to two bidentate diimine ligands (2,2′-bipyridine or 1,10-phenanthroline) and one bidentate monobasic flavonoid ligand through 3,4-site of quercetin, morin, and 3-hydroxyflavone or 4,5-site of chrysin. Complexes bind CT DNA by intercalation and binding constants comparable to ethidium bromide or 10 times higher. Binding constants of complexes to BSA were several times higher compared to ibuprofen and diazepam, and suggest that the complexes have a strong affinity to BSA. Antioxidant activity tests showed that the complexes are more potent in terms of radical inhibition compared to the parent flavonoids. Cytotoxic testing revealed that the Ru(II) complex of quercetin with 2,2′-bipyridine co-ligand has good selectivity to breast adenocarcinoma, while the complex of 3-hydroxyflavone with 2,2′-bipyridine co-ligand showed strong cytotoxicity toward all tested cell lines with IC50 ~ 1 μM. All complexes showed moderate activity toward Acinetobacter baumannii, while the Ru(II) complex of 3-hydroxyflavone with 2,2′-bipyridine showed excellent activity toward MRSA and Candida albicans. 相似文献
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新工科的人才培养目标使混合式教学模式成为高校教学改革的重要趋势。云教材是与混合式教学模式相契合的教学资源。工程力学云教材的建设贯彻以成果为导向的教育理念,明确学习目标,集成富媒体数字出版、云服务和移动学习三大领域的前沿技术,为工程力学混合式教学提供配套的教学资源。实践应用表明,工程力学云教材提高了学生的学习兴趣和自主学习能力,助力新工科的建设。 相似文献
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