Fused Perylene–Phthalocyanine Macrocycles: A New Family of NIR‐Dyes with Pronounced Basicity

The synthesis and characterization of a new type of chromophore, namely PePc consisting of a central phthalocyanine core and four fused perylene–bisimide (PBI) units is described for the first time. The entire architecture represents a highly extended conjugated heterocyclic π‐system with C_4h symmetry. In order to guarantee pronounced solubility in organic solvents the corresponding PBI units were bay‐functionalized with tert‐butylphenoxy substituents. Next to the metal‐free macrocycle, PePcH₂, also metallated macrocycles PePcM (M=Zn, Ni, Pb, Ru, Fe) were synthesized. The extensive fusion of the corresponding aromatic building blocks to the very large extended π‐system leads to a very narrow HOMO–LUMO gap and as a consequence to transparency in the visible but light absorption in the NIR region. Significantly, the azomethine N‐atoms N1?N4 of PePcM and PePcH₂ are highly basic. The corresponding tetraprotonated systems can only be deprotonated with very strong non‐nucleophilic bases such as phosphazene bases. In the protonated forms PePcMH₄⁴⁺ and PePcMH₆⁴⁺ the absorption maximum is shifted back to the visible region due to the loss of conjugation. The experimental findings were corroborated with quantum mechanical calculations.     

对新时期分析测试中心定位的思考

就如何理解和看待新时期分析测试中心的定位和发展,如何解决分析测试中心在结构和管理上存在的固有问题提出了粗略的观点.希望对分析测试中心的发展起到抛砖引玉的作用.     

The Current Directions of Searching for Antiparasitic Drugs

Parasitic diseases are still a huge problem for mankind. They are becoming the main cause of chronic diseases in the world. Migration of the population, pollution of the natural environment, and climate changes cause the rapid spread of diseases. Additionally, a growing resistance of parasites to drugs is observed. Many research groups are looking for effective antiparasitic drugs with low side effects. In this work, we present the current trends in the search for antiparasitic drugs. We report known drugs used in other disease entities with proven antiparasitic activity and research on new chemical structures that may be potential drugs in parasitic diseases. The described investigations of antiparasitic compounds can be helpful for further drug development.     

Operating principles of the cerebral cortex as a six-layered network in primates: beyond the classic canonical circuit model

The cerebral cortex performs its computations with many six-layered fundamental units, collectively spreading along the cortical sheet. What is the local network structure and the operating dynamics of such a fundamental unit? Previous investigations of primary sensory areas revealed a classic “canonical” circuit model, leading to an expectation of similar circuit organization and dynamics throughout the cortex. This review clarifies the different circuit dynamics at play in the higher association cortex of primates that implements computation for high-level cognition such as memory and attention. Instead of feedforward processing of response selectivity through Layers 4 to 2/3 that the classic canonical circuit stipulates, memory recall in primates occurs in Layer 5/6 with local backward projection to Layer 2/3, after which the retrieved information is sent back from Layer 6 to lower-level cortical areas for further retrieval of nested associations of target attributes. In this review, a novel “dynamic multimode module (D3M)” in the primate association cortex is proposed, as a new “canonical” circuit model performing this operation.     

OLED器件新型应用研究进展

有机发光二极管(organic light-emitting diodes,OLED)具有可柔性制备、低驱动电压、低功耗等优点,近年来技术上的突飞猛进及其广泛的应用前景,使之成为平板显示、新型照明、可穿戴,以及智能电子产品开发中最热门的研究课题之一.作为新一代的显示及照明技术,小尺寸OLED显示器已实现商业化,大尺寸O...     

Single top partner production in the tZ channel at eγ collision in the littlest Higgs model with T-parity

Introducing the top partner is a common way to cancel the largest quadratically divergent contribution to the Higgs mass induced by the top quark. In this work, we study single top partner production in the tZ channel at eγ collision in the littlest Higgs model with T-parity(LHT). Since it is well known that polarized beams can enhance the cross section, we analyze the signal via polarized electron beams,and photon beams. we have selected two decay modes for comparison, based on the leptonic or the hadronic decays of the W and Z from the top partner. We then construct a detailed detector simulation, and choose a set of cuts to enhance signal significance. For mode A(B), the capacity for exclusion in this process at s~(1/2)=3TeV is comparable to the current experimental limits with L=1000(500) fb~(-1). If the integrated luminosity can be increased to 3000 fb~(-1), the top partner mass+mTcan be excluded up to 1350(1440) GeV at 2σ level. We also considered the initial state radiation effect, and find that this effect reduces the excluding ability of the eγ collision on the the top partner mass by approximately 10 GeV. Moreover, the ability to exclude the LHT parameter space at eγ collision complements the existing research.     

Multi-variable special polynomials using an operator ordering method

Using an operator ordering method for some commutative superposition operators, we introduce two new multi-variable special polynomials and their generating functions, and present some new operator identities and integral formulas involving the two special polynomials. Instead of calculating complicated partial differential, we use the special polynomials and their generating functions to concisely address the normalization, photocount distributions and Wigner distributions of several quantum states that can be realized physically, the results of which provide real convenience for further investigating the properties and applications of these states.     

Experimental review of the ϒ(1S, 2S, 3S) physics at e+e− colliders and the LHC

The three lowest-lying \mathrm{\Upsilon } states, i.e., \mathrm{\Upsilon }(1S), \mathrm{\Upsilon }(2S), and \mathrm{\Upsilon }(3S), composed of bb¯ pairs and below the BB ¯ threshold, provide a good platform for the researches of hadronic physics and physics beyond the Standard Model. They can be produced directly in e⁺e⁻ colliding experiments, such as CLEO, Babar, and Belle, with low continuum backgrounds. In these experiments, many measurements of the exclusive \mathrm{\Upsilon }(1S) and \mathrm{\Upsilon }(2S) decays into light hadrons, which shed light on the “80% rule” for the Okubo–Zweig–Iizuka suppressed decays in the bottomonium sector, were carried out. Meanwhile, many studies of the charmonium and bottomonium productions in \mathrm{\Upsilon }(1S, 2S, 3S) decays were performed, to distinguish different Quantum Chromodynamics (QCD) models. Besides, exotic states and new physics were also extensively explored in \mathrm{\Upsilon }(1S, 2S, 3S) decays at CLEO, BaBar, and Belle. The \mathrm{\Upsilon }(1S, 2S, 3S) states can also be produced in pp collisions and in collisions involving heavy ions. The precision measurements of their cross sections and polarizations at the large hadron collider (LHC), especially in the CMS, ATLAS, and LHCb experiments, help to understandΥproduction mechanisms in pp collisions. The observation of the sequentialΥsuppression in heavy ion collisions at CMS, LHCb, and ALICE is of great importance for verifying the quark–gluon plasma predicted by QCD. In this article, we review the experimental results on \mathrm{\Upsilon }(1S, 2S, 3S) at e⁺e⁻ colliders and the LHC, and summarize their prospects at Belle II and the LHC.     

Synthesis and Crystal Structure of 4,4＂-Diamino-N,N＇-diethyl Bisbenzenesulfamide

A new compound of 4,4'-diamino-N,N'-diethyl bisbenzenesulfamide (C18H26N4O4S2,Fw = 426.55) has been synthesized and its structure was determined by X-ray crystallography method. The crystal belongs to the monoclinic system, space group P21/c with a = 10.0623(9), b =13.6759(13), c =15.5309(14) (A),β = 100.482(2)°, V= 2101.6(3)(A)3, Dc = 1.348 g/cm3, F(000) = 904,μ = 0.285 mm-1, Z = 4, the final R = 0.0512 and wR = 0.1363 for 3485 observed reflections with I ＞2σ(Ⅰ). The structure of the title compound is pseudo secondary axisymmetric, and the two sulfamide-groups show distorted tetrahedral configurations.     

1H,13C NMR spectral data for α-, β-, and γ-lewisites and identification ofcis,trans, trans-γ-lewisite as a new isomer

The¹H and¹³C NMR spectral parameters of α-, β-, and y-lewisites1–5 were obtained and a new isomer,cis,trans,trans-γ-lewisite5, was isolated and identified on the basis of chemical shifts, relative intensities of the signals, and the intra-chain (³ J _hh ,³ J _ch ) and interchain (³ J _casch ) coupling constants. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 1833–1835, October, 1993.