Perturbation analysis of theGI/GI/1 queue

We examine a family ofGI/GI/1 queueing processes generated by a parametric family of service time distributions,F(x,), and we show that under suitable conditions the corresponding customer stationary expectation of the system time is twice continuously differentiable with respect to. Expressions for the derivatives are given which are suitable for single run derivative estimation. These results are extended to parameters of the interarrival time distribution and expressions for the corresponding second derivatives (as well as partial second derivatives involving both interarrivai and service time parameters) are also obtained. Finally, we present perturbation analysis algorithms based on these expressions along with simulation results demonstrating their performance.     

Reaction of 2,6-dibenzylidenecyclohexanone with phosphorus pentachloride: Triple functionalization of the isosemiquinoid system

The reaction of 2,6-dibenzylidenecyclohexanone with PCl₅ occursvia the sequential stages of desoxychlorination and substitutional phosphorylation to form (after oxidation, methoxylation, and hydrolysis on the surface of the chromatographic SiO₂ adsorbent) organophosphorus products of the 1-(a-chloro-, a-hydroxy-, or -alkoxy)benzyl-2-chloro-3-(-(dimethylphosphoryl)benzylidene)cyclobex-1-ene series.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 441–443, February, 1996.     

Determination of fluoroquinolone antibacterials as N-acyl derivatives

Summary A simple and quantitative method for the preparation and high performance liquid chromatography (HPLC) of N-acylated fluoroquinolones has been developed. The acylation procedure was performed with four different acid anhydrides and found to be applicable to several fluoroquinolones. The acylated derivatives were chromatographed directly on a Nucleosil C₁₈ column without the necessity of further sample manipulation. Detector response for the N-acetyl derivatives of norfloxacin, ciprofloxacin, sarafloxacin, and temafloxacin was linear to at least 50 g/mL. The retention behavior of the N-acyl derivatives can be predicted by the length of the carbon chain of the amide.     

Enantioselective synthesis of hydroxy-substituted α-methyl-α-amino acids using Al and Mn derivatives of cyclo-(L-Ala-L-AIa) bis-Iactim ethers

Aluminum and manganese derivatives of lithiated bis-lactim ethers of cyclo-(L-Ala-L-Ala) were used for the enantioselective synthesis of -hydroxy and polyhydroxy -amino acids of the 2-methyIserine series. A new variant of the synthesis of these acids via 3-acyl-2, 5-dialkoxy-3, 6-dimethyl-3, 6-dihydropyrazines is proposed.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 590–595, March, 1993.     

Synthesis and some properties ofN-polynitromethyl derivatives of fused benzotriazoles

The procedures for the synthesis ofN-polynitromethyl derivatives of benzo[1,2-d;4,5d]ditriazole-4,8-dione are described. Some chemical properties of the compounds obtained are investigated.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 9, pp. 1623–1625, September, 1993.     

Paradigms and Paradoxes: Thoughts on the Enthalpy of Formation of Guanidine and Its Monosubstituted Derivatives

Despite their seeming simplicity, substituted guanidines have not particularly caught the attention of the thermochemical community. The current paper compares the enthalpy of formation of solid substituted guanidines with correspondingly substituted benzenes, also as solids.     

Synthesis, Crystalline Structure, and Spectra of 3,3-Dimethyl-1-(3-methyl-1-phenylpyrazol-5-onylidene-4)-1,2,3,4-tetrahydroisoquinoline

3,3-Dimethyl-1-(3-methyl-1-phenylpyrazol-5-onylidene-4)-1,2,3,4-tetrahydroisoquinoline has been synthesized and its crystalline and molecular structures determined. It was found by IR and electronic absorption spectroscopic methods that the structure of this compound is not changed in solutions.     

Transformations ofmyo-inositol hexa-O-nitrate under the action of amines

Reactions ofmyo-inositiol hexa-O-nitrate with ammonia and primary amines yield tetrahydroxy-1,4-benzoquinone derivatives,viz., its tetraammonium salt and its diimines, respectively. Reactions with secondary and tertiary amines give salts of rhodizonic acid, which are converted into salts of croconic acid under certain conditions. The reactions with secondary amines involve intermediate formation of radical species, which were dectected by ESR spectroscopy. A scheme for the chemical transformations ofmyo-inositol hexa-O-nitrate under the action of amines was proposed.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2962–2967, December, 1996.     

A unique reversal of elution order during direct enantiomeric resolution of amide derivatives of 1-phenyl-2-aminopropane by high performance liquid chromatography on chiral stationary phases

Enantiomeric amide derivatives of (S)- and (R)-1-phenyl-2-aminopropane (dextro- and levoamphetamine, respectively) were resolved by high performance liquid chromatography on commercially available ionically and covalently bonded chiral stationary phases ((R)-N-(3,5-dinitrobenzoyl)phenylglycine). Ten enantiomeric amide pairs were synthesized and chromatographed on the columns by using a mobile phase of hexane-isopropanol (97 : 3), a flow rate of 2 ml/min, and a column temperature of 20°C. The (R)-isomer of all 10 amides eluted first on the covalent column as did the (R)-isomer of nine derivatives on the ionic column. however, the 3,5-dinitrobenzoyl amide of (S)- amphetamine eluted before the (R)-isomer on the ionic column. This reversal in enantiomeric elution order reveals the complexity of the interactions occurring on these columns and emphasizes the hazards of relying on observed elution order as an a priori indication of absolute configuration.     

Synthesis and electronic properties of pentacene derivatives as promising n-type semiconductor candidates

Two pentacene derivatives 1 and 2 were synthesized from the Diels-Alder reactions of furan derivatives with 1,4-benzoquinone. They were characterized by the methods of ¹H — nuclear magnetic resonance spectroscopy (¹H-NMR), matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS), ultraviolet and visible spectrophotometry (UV-VIS), photoluminescence (PL) spectrometry and cyclic voltammetry (CV). The energy gaps of 1 and 2, taken directly from spectroscopic measurements, are broad as 2.72 and 2.46 eV, leading to blue and greenish blue photoluminescence, respectively. The LUMO and HOMO energy levels are −2.77 and −5.49 eV for 1, and −2.91 and −5.37 eV for 2, respectively. The low energy levels make both 1 and 2 good air-stabilities and promising n-type semiconductor candidates for use in organic electronics.