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51.
Ken Kusakari Tadao Fukuhara Nobuhiko Ochiai Takashi Watanabe Yukihiro Sugimoto 《Natural product research》2016,30(8):954-959
Three known iridoid glucosides (gentiournoside A, gentiournoside E and depressoside) were isolated from the flowers of Gentiana urnula Harry Sm. through activity-guided fractionations with a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. All three compounds exhibited excellent DPPH radical scavenging activities (IC50: 10–20 μmol L?1) comparable to that of ascorbic acid and Trolox. However, examination of the NMR data revealed that the reported chemical structure of depressoside, previously isolated from the leaves of G. depressa, needed correcting due to incorrect elucidation around C-7 of the iridane skeleton, and was corrected to 6-β-(2,3-dihydroxyphenyl)-d-glucosyl 7-O-(2,3-dihydroxybenzoyl)-loganate. Depressoside exhibited a much higher scavenging activity against superoxide radicals (IC50: 45.5 μmol L?1) than the other two extracted compounds (IC50: more than 900 μmol L?1) due to the crucial presence of a pyrogallyl unit. 相似文献
52.
Yong-Mei Ren Chang-Qiang Ke Chunping Tang Sheng Yao Yang Ye 《Tetrahedron letters》2017,58(24):2385-2388
Divaccinosides A–D (1–4), four rare iridoid glucoside cyclodimers in the truxillate forms, were characterized from the leaves of Vaccinium bracteatum. They were presumably biosynthesized from two known iridoid glucoside monomers, vaccinoside (5) and 10-O-trans-p-coumaroyl-6α-hydroxyl-dihydromonotropein (6), via a [2+2] cycloaddition reaction. The structures of the new compounds were established by comprehensive spectroscopic measurements, combined with chemical conversions and single crystal X-ray crystallographic analyses. 相似文献
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54.
Ai‐Xue Zuo Yong Shen Zhi‐Yong Jiang Xue‐Mei Zhang Jun Zhou Jun Lü Ji‐Jun Chen 《Helvetica chimica acta》2010,93(3):504-510
Three new phenolic glucosides named orcinosides A, B, and C ( 1, 2 , and 3 , resp.) were isolated in low yields (4.0×10−6, 11.5×10−6, 4.5×10−6%, resp.) from the rhizomes of Curculigo orchioides. Their structures were elucidated by comprehensive spectroscopic analyses including FAB‐MS, HR‐ESI‐MS, IR, and 1D‐ and 2D‐NMR (HSQC, HMBC) data. Compounds 1 – 3 contained two orcinol‐glucoside moieties linked through a CH2 group. 相似文献
55.
Xue Song Feng Yang Qu Zhao Hua Wu Lei Xu Dong Song Zhang Hui Yuan Gao Li Jun Wu 《中国化学快报》2009,20(6):702-705
Chemical investigation of Syringa velutinai Kom. led to the isolation of two new secoiridoid glucosides. Their structures were identified as 6'-O-(6, 7-dihyrofoliamenthoyl)-8-epi-kingisidic acid (syrveoside A, 1) and 6'-O-menthiafoloyl-8-epi-kingisidic acid (syrveoside B, 2) on the basis of chemical and physicochemical evidence. 相似文献
56.
Ren‐Qiang Mei Qing Lu Yan‐Fen Hu Hai‐Yang Liu Fu‐Kai Bao Yu Zhang Yong‐Xian Cheng 《Helvetica chimica acta》2008,91(1):90-96
Three new linear C14 polyyne (=polyacetylene) glucosides, cordifolioidynes A–C ( 1 – 3 ), together with two known polyynes, lobetyol ( 4 ) and lobetyolin ( 5 ), and five known phenylpropanoids, i.e., sinapinaldehyde ( 6 ), coniferaldehyde ( 7 ), coniferoside ( 8 ), sachaliside ( 9 ), and isoconiferin ( 10 ), were isolated from the roots of Codonopsis cordifolioidea. The structures of 1 – 3 were established from spectral evidences and by characterization of their hydrolysis products. Acid hydrolysis of 1 afforded the aglycone 1a , while hydrolysis of 2 and 3 gave the cyclization products 2a and 3a , respectively. Compounds 4 – 10 were isolated from this plant for the first time. The antibacterial activity of compounds 1 – 5 were assessed against eight microbial strains by the agar dilution method, none of them exhibited antibacterial effects at concentrations up to 100 μg/ml. 相似文献
57.
Derya Gülcemal Milena Masullo Ozgen Alankuş‐Çalışkan Tamer Karayıldırım Serdar G. Şenol Sonia Piacente Erdal Bedir 《Magnetic resonance in chemistry : MRC》2010,48(3):239-243
A new secondary metabolite, pterocephaline, along with the known cantleyoside, 7α‐morroniside, 3β,5α‐tetrahydrodesoxycordifoline lactam, 5S‐5‐carboxyvincoside, sweroside, and loganin have been isolated from the aerial parts of P. pinardii (Dipsacaceae). Moreover, cantleyoside‐methyl‐hemiacetal and cantleyoside‐dimethyl‐acetal were obtained as seco‐iridoid artifacts. The structures were elucidated by extensive spectroscopic methods including 1D‐(1H, 13C and TOCSY) and 2D‐NMR (DQF‐COSY, HSQC and HMBC). Monoterpenoid glucoindole alkaloids were encountered for the first time in Dipsacaceae family. Copyright © 2010 John Wiley & Sons, Ltd. 相似文献
58.
Hyun-Jung Lee Oh-Kyu Lee Yeong-Han Kwon Don-Ha Choi Ha-Young Kang Hyeon-Yong Lee Ki-Hyon Paik Hak-Ju Lee 《Chemistry of Natural Compounds》2006,42(4):415-418
Four known isoflavone glucosides have been isolated from the bark of Amorpha fruticosa, which is a traditional remedy plant,
for the first time. They were elucidated as 3′-hydroxy-4′-methoxyisoflavone-7-O-β-D-glucopyranoside (1), 4′,6-dimethoxyisoflavone-7-O-β-D-glucopyranoside (2), 4′-methoxyisoflavone-7-O-β-D-glucopyranoside (3), and 3′,5-dihydroxy-4′-methoxyisoflavone-7-O-β-D-glucopyranoside (4), based on the UV, FT-IR, EIMS, FABMS, HREIMS, and NMR (1H and 13C, DEPT, COSY, NOESY, HMQC, and HMBC) data.
Published in Khimiya Prirodnykh Soedinenii, No. 4, pp. 336–338, July–August, 2006. 相似文献
59.
Clerodendrumserratumcalledas"SanDuiJie"inChinese,isasmallshrubwithfragrantflowersfoundwidelyintheforestsofthesouthofChina.IthasbeenusedasafolkmedicineinYunnanfortreatmentofmanydiseasessuchashepatitisandmalaria.Inordertofindthebioactivecomponents,studiesonthechemicalconstituentsoftheleavesofClerodendrumserratum,collectedatLongLingofYunnanprovince,werecarriedout.Wehavereportedtwonewglycosidespreviously'.NoW,furtherinvestigationofglycosidesofthisplantresultedintwonewiridoidglucosides76coumar… 相似文献
60.
Peng‐Cheng Fan Mao‐Xing Li Hui‐Ping Ma Lin‐lin Jing Jian‐guo Qiu Zheng‐Ping Jia 《Biomedical chromatography : BMC》2012,26(12):1543-1551
A simple and sensitive high‐performance liquid chromatography/tandem mass spectrometry (LC/MS/MS) method was developed and validated for simultaneous determination of shanzhiside methylester and its three derivatives in rabbit plasma. The method showed good linearity and no endogenous material interfered with the marked compounds and internal standard (IS) capatol peaks. Samples were processed by acetonitrile precipitation. Chromatography was performed using a C18 column (150 × 3.9 mm i.d., 4 µm). The mobile phase consisted of methanol and water (60:40, v/v) during a total run time of 7 min. The main mass parent ions and daughter ions pairs (m/z) for monitoring were: shanzhiside methylester, 429.0/267.4; 8‐O‐acetyl shanzhiside methylester, 470.9/411.3; loganin, 413.2/251.4; phloyoside II, 479.2/281.3; and IS 385.2/203.3. Finally, the method was applied to a pharmacokinetic study of rabbits following intravenous administration of iridoid glycosides extracted from traditional herb Lamiophlomis rotata. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献