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991.
以人红细胞作为过氧化氢酶的来源,用尼龙网共价键合,并与氧电极合制得过氧化氢传感器,研究了尼龙网上活化酶的固定化,测试介质等有关实验条件和参数,测得在pH8的磷酸盐缓冲溶液中,电极响应的线性范围为3×10^-5~3×10^-3mol/L,测定了传感器在果珍,鱼浆和磷酸盐缓冲溶液中对过氧化氢的回收率,获得满意结果。 相似文献
992.
A mathematical model consisting of a system of two ordinary differential equations is formulated to represent the interrelationship
between healthy and radiated cells at a given cite. Three different modes of radiation are considered: constant, decaying,
and periodic radiation. For the constant case, precise criteria for persistence and extinction are obtained. In the decaying
case, it is shown that the radiated cells always become extinct. Finally in the periodic case, criteria are obtained for a
perturbed positive periodic solution.
Dedicated to the memory of Professor Miklós Farkas 相似文献
993.
Ruth L. Greenstein 《Applied biochemistry and biotechnology》1985,11(6):489-506
In late 1984, the Reagan administration proposed a Coordinated Framework for Regulation of Biotechnology. Its proposed regulatory
approach appears less constraining than the deep concerns of the 1970s concerning the risk of biotechnology would have suggested.
Several distinctive characteristics of the early period of biotechnology, particularly the role of the research community
in developing the initial regulatory system and the extent of federal funding, explain this development. The administration’s
proposal may attract substantial support. However, implementation may lead to conflicts and problems, especially concerning
human germ-line gene therapy and environmental release of viable genetically engineered organisms. 相似文献
994.
Organotins are currently one of the most studied groups of organometallic compounds; their novel and often unique chemical properties have intrigued chemists for over 100 years and, today, many of these compounds find extensive use in agriculture and industry. Over the years, however, a number of the organotins have been demonstrated to be toxic and there is now increasing concern that their widespread use may cause adverse effects within environmental and biological systems. This article reviews and updates the current literature concerning organotin toxicology. It identifies the various target organs and systems, discusses mechanisms and species susceptibility, and directs the reader to additional sources of more specialized information as appropriate. 相似文献
995.
R L Kamman K G Go F A Muskiet G P Stomp P Van Dijk H J Berendsen 《Magnetic resonance imaging》1984,2(3):211-220
Proton spin longitudinal (T1) and transverse (T2) relaxation and proton density studies were carried out on human fatty tissue and bovine white matter, both in the native state and after immersion in D2O. It is concluded that nuclear magnetic resonance signals from fatty tissue result mainly from methyl and methylene protons of hydrocarbons. No contribution from lipid protons could be detected for white matter, although it contains a high percentage of lipids. Imaging experiments, resulting in T1, T2, and proton density maps, support the results obtained with spectroscopic relaxation studies. 相似文献
996.
The advent of nuclear reactors ushered in an era of increasing number of sources of ionizing radiations. However, the potential
of ionizing radiations to cause harmful effects was recognized soon after the discovery of x-rays and radioactivityi.e. long before the building of nuclear reactors. Therefore, protection against ionizing radiations has been of paramount concern
and has guided the development of atomic energy and related fields. The advances in technology in general resulted in an increase
in accidents causing injury and death. It was realised that even medicines, food additives and a host of other substances
of daily use had injurious side effects. Smoking was found to be extremely harmful. From these emerged the concepts of quantitative
and relative risks. This article discusses briefly the concept of riskvis-a-vis ionizing radiations and approaches to protection against them. 相似文献
997.
998.
We describe a new fluorescence imaging device for clinical cancer photodetection in hollow organs in which the tumor/normal
tissue contrast is derived from the fluorescence lifetime of endogenous or exogenous fluorochromes. This fluorescence lifetime
contrast gives information about the physicochemical properties of the environment which are different between normal and
certain diseased tissues. The excitation light from a CW laser is modulated in amplitude at a radio frequency by an electrooptical
modulator and delivered by an optical fiber through an endoscope to the hollow organ. The image of the tissue collected by
the endoscope is separated in two spectral windows, one being the backscattered excitation light and the other the fluorescence
of the fluorochrome. Each image is then focused on the photocathode of image intensifiers (II) whose optical gain is modulated
at the same frequency as the excitation intensity, resulting in homodyne phase-sensitive images. By acquiring stationary phase-sensitive
frames at different phases between the excitation and the detection, it is possible to calculate in quasi-real time the apparent
fluorescence lifetime of the corresponding tissue region for each pixel. A result obtained by investigating the endogenous
fluorochromes present in the mucous membrane of an excised human bladder is presented to illustrate this method and most of
the optical parameters which are of major importance for this photodetection modality have been evaluated. 相似文献
999.
A. Ruebner D. Kirsch S. Andrees W. Decker B. Roeder B. Spengler R. Kaufmann J.G. Moser 《Journal of inclusion phenomena and macrocyclic chemistry》1997,27(1):69-84
The aim of our investigation was to develop carrier systems for an application of inert drugs in photodynamic cancer therapy. -Cyclodextrin dimers linked at their primary and secondary faces by spacers of varying lengths were synthesized as carrier systems. The binding constants of the inclusion complexes of these cyclodextrin dimers and porphyrinoid photosensitizers were determined by competitive spectrofluorometry. Particularly the secondary face linked dimers exhibited extremely high binding constants with values of 106-107 L/mol. Theoretical studies were carried out on these inclusion complexes to confirm the influence of spacer length and connecting side on complex stability. 相似文献
1000.
高效液相色谱法测定血清中的鸟氨酸脱羧酶活性 总被引:1,自引:0,他引:1
建立了血清中鸟氨酸脱羧酶活性的高效液相色谱测定法。结果表明,腐胺在2.8~45.5μmol/L范围内线性关系良好。最低检测量为0.05nmol,回收率为85.06%,RSD为8.91%。本法测定正常人及乳腺癌、宫颈癌患者血清中的鸟氨酸脱羧、酶活性发现,乳腺癌及宫颈癌血清中的酶活性升高(p<0.05),说明测定血清的鸟氨酸脱羧酶活性,对诊断肿瘤有一定的临床意义。 相似文献