一氧化氮化学性质的研究进展

概括了由Louis J. Ignarro, Ferid Murad和Robert F. Furchgott三位诺贝尔奖获得者提出的一氧化氮作为血管内皮松弛因子(EDRF)的作用机制及生物学意义; 同时也总结了100多年来一氧化氮在化学本质的探讨方面做出的研究成就; 归纳了一氧化氮自由基在化学反应过程中的行为本质.     

五元杂环类茂金属配合物研究进展

综述了五元杂环类茂金属配合物的研究进展及其在烯烃聚合中的应用.     

Isoflavone-based trimer liquid crystals: synthesis,characterization, thermal and mesomorphic properties evaluations

ABSTRACT

A new homologous series of mesogens with isoflavone heterocycle have been synthesised and characterised. The symmetric molecular structure consists of middle ethylene/phenylenediamine and peripheral isoflavone and biphenyl cores as trimer fragments. Chemical structures were evaluated using IR, NMR and CHN techniques. Thermal, mesophase behaviours and textural types are studied by DSC and POM instrumentations. Most of the compounds are favouring liquid crystalline behaviours with Smectic and nematic mesophases.     

Omriolide A and B; two new rearranged spongian diterpenes from the marine sponge Dictyodendrilla aff. retiara

Two new rearranged spongian diterpenes designated omriolide A and B were isolated from the southern Kenyan sponge Dictyodendrilla aff. retiara collected at Wasini Is., Shimoni Channel. Omriolide A possesses an octalin linked to a unique trioxatricyclo[5.2.1.0^4,10]decane ring system, forming a tricyclic ‘cap’. Omriolide B comprised a tricyclo[5.4.0.0^2,4]undecane linked to a dioxabicyclo[3.3.0]octane. The structures of both diterpenes were elucidated by interpretation of MS results and, mainly, 1D and 2D NMR spectra.     

Crystal Structure of 3－［（α－Phenyl） triphenyl germylethyl］－4－phenyl－Δ~2－1，2，4－triazoline－5－thione

ＣｒｙｓｔａｌＳｔｒｕｃｔｕｒｅｏｆ３－［（α－Ｐｈｅｎｙｌ）ｔｒｉｐｈｅｎｙｌｇｅｒｍｙｌｅｔｈｙｌ］－４－ｐｈｅｎｙｌ－Δ~２－１，２，４－ｔｒｉａｚｏｌｉｎｅ－５－ｔｈｉｏｎｅＣｈｅｎＲｕ－Ｙｕ；ＬｉＦｅｎｇ－Ｆｕ（ＩｎｓｔｉｔｕｔｅｏｆＥｌｅ?..     

Synthesis and Crystal Structure of 1-(o-methylphenyl)-2-(p-methoxyphenyl)-1,3,2-diazaphospholidin-4-thione-2-sulfide

11NTRODUCTIoNThederivativesofdiazaphospholidinoneorthecorrespondingthionesareknowntopossessinterestingbiologicalproperties,suchasherbicidalactivity"'2i.Inrecentyears,itwasreportedthatthel,4,2-diazaphospholindine-5-thione-2havegoodselectiveherbicidalactivity"'41.Tolookformoreeffectiveherbicideswithlowtoxicity,aseriesofnovel1-(o-methylphenyl)-2-(p-methoxyphenyl)-phospholidin-4-thione-sulfideshavebeensynthesizedandtheirmolecularstructuresstudied.PreliminarybioassaysshowthatthesecomPoundshaveg…     

Microwave-assisted multi-component synthesis of fused 3-aminoimidazoles

A variety of fused 3-aminoimidazoles have been synthesised by a microwave assisted Ugi three-component coupling (3cc) reaction catalysed by scandium triflate in methanol as solvent. Yields of 33-93% have been achieved after just 10 min of microwave irradiation using a simple one-stage procedure. The methodology described is suitable for the rapid and efficient synthesis of a range of fused heterocycles of pharmacological interest.     

Theoretical Design of High‐spin Organic Molecules with —·N—N— as a Spin‐containing Fragment and Heterocycles as an End Group

Novel stable high spin molecules possessing three different arranged fashions are designed with –·N–N< as a spin‐containing (SC) fragment, various aromatic, such as benzene ( 1 ), pyridine ( 2 ), pyridazine ( 3 ), pyrimidine ( 4 ), pyrazine ( 5 ), triazine ( 6 ) as end groups (EG) and phenyl as a ferromagnetic coupling (FC) unit. The effects of a different end groups on the spin multiplicities of the ground states and their stabilities were investigated by means of AM1‐CI approach. It has been found that the spin densities on the two atoms of the SC fragment are different from delocalization resulting in the specific stability of –·N–N<. In these molecules, the stabilities of the triplet states decrease when the distance between the atoms of central SC (–N–) increases. The orders of the stability of triplet states for 1an , 1bn , 1cn [They are isomers in which SC is connected with FC in different way ( 1an , N₁NNN₁; 1bn , N₁N N₁N; 1cn , NN₁N₁N) and six heterocycles are EG] show that the stability of triplet states with heterocycles as end groups is higher than that with phenyl as end groups, and in the order:triazine (EG)>pyrimidine, pyrazine>pyridine, pyridazine.     

不饱和烯酸酰基硫脲化合物的合成与抑菌活性测定

采用山梨酸和肉桂酸为先导化合物,经过酰氯化和硫脲化,引入活性的环状化合物,合成了6个新化合物,经核磁共振氢谱、红外光谱和元素分析测定,确认了新化合物的结构.在此基础上对目标化合物进行了防治辣椒枯萎病菌、小麦赤霉病菌、马铃薯晚疫病菌的生物活性测试.结果表明,部分化合物有一定的抑菌活性.     

Aminoamidines. 5. Synthesis and acetylation of N,N1,N2-triaryl-substituted β-aminoamidines

Triaryl-substituted -aminoamidines were obtained by the reaction of ,-unsaturated N-arylimidoyl chlorides with arylamines. Acylation of the products gave the products from monosubstitution at the -amino group. Triaryl-substituted -aminoamidines react with phosgene and with oxalyl chloride to form 4-aryliminoperhydropyrimidin-2-ones and 5-aryliminoperhydro-1,4-diazepine-2,3-diones, respectively.For previous communication, see [1].A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan' Scientific Center, Russian Academy of Sciences, 420083 Kazan'. Translated fromIzvestiya Akademii Nauk, Seriya Khimicheskaya, No. 11, pp. 2633–2642, November, 1992.