Convenient Synthesis of Pyrazolo[4′,3′:5,6]pyrano[4,3-c][1,2]oxazoles via Intramolecular Nitrile Oxide Cycloaddition

A simple and efficient synthetic route to the novel 3a,4-dihydro-3H,7H- and 4H,7H-pyrazolo[4′,3′:5,6]pyrano[4,3-c][1,2]oxazole ring systems from 3-(prop-2-en-1-yloxy)- or 3-(prop-2-yn-1-yloxy)-1H-pyrazole-4-carbaldehyde oximes has been developed by employing the intramolecular nitrile oxide cycloaddition (INOC) reaction as the key step. The configuration of intermediate aldoximes was unambiguously determined using NOESY experimental data and comparison of the magnitudes of ¹J_CH coupling constants of the iminyl moiety, which were greater by approximately 13 Hz for the predominant syn isomer. The structures of the obtained heterocyclic products were confirmed by detailed ¹H, ¹³C and ¹⁵N NMR spectroscopic experiments and HRMS measurements.     

7-[3-氨基-3-(4-甲氧苯基)丙酰基]-3-三氟甲基-5,6,7,8-四氢[1,2,4]三唑并[4,3-α]哌嗪的合成与表征

以2-氯吡嗪和对甲氧基苯甲醛为原料,经肼解、三氟乙酰化、闭环、氢化、缩合、脱保护基等一系列反应合成了新的稠合三唑衍生物:7-[3-氨基-3-(4-甲氧苯基)丙酰基]-3-三氟甲基-5,6,7,8-四氢[1,2,4]三唑并[4,3-α]哌嗪,目标化合物及中间体经IR、NMR、MS予以确证.     

分子中芳香性自动识别算法

以图论为基础,从化合物的二维连接表出发,在环识别算法的约束下,对分子中的节点进行判断。结果表明,该算法能够识别大多数化合物中的芳香性。作为约束条件,把芳香性的识别算法应用于ESESOC系统中结构的穷举生成,得到了较好的结果。     

中心多项式与环的交换性

本文证明了环的一个交换性定理,它是文献[6-8]中相应结论的推广,     

φ900带软硬环的土平面波加载器研制

介绍了用于抗爆试验研究的φ900带软硬环的土平面波加载器的研制过程、静力与动力验证试验,由于采用了软硬环试验箱体以保证箱体的轴向柔性及径向刚性技术,验证性试验比较好地模拟了介质的一维平面应变运动,验证性试验结果表明该试验装置得到了预期的设计要求。     

光纤熔锥耦合器的声光调制特性

对光纤熔锥方向耦合器的声光强度调特性进行了实验研究,得到了工作波长为1310nm、声波频率为20.19kHz,电驱动功率为2.6mW,插入损耗为0.5dB,调制深度为64％的声光强度调制特性。     

Definition and use of an Oxoacidity Function ω for the Comparison of Acidity Levels at Iooo K of Some Chloride Melts Involved in Electrometalluric Processes

Abstract

Many molten chlorides are used in industry for the electrolytic production of metals. In such processes, the oxoacidity level is crucial with respect to the cost and the yield.

The determination and the comparison of the oxoacidic properties of chloride melts then appears to be of practical interest. Such a comaprison is described applying a similar process to that used for pH scales in room temperature solvents. Purification processes of such melts are then explained quantitatively.