乌骨鸡活性肽对体外非酶糖基化的抑制作用

采用正交实验优化了体外非酶糖基化反应体系,体系中加入不同浓度的乌骨鸡活性肽I、Ⅱ37 ℃孵育,同时以肌肽为阳性对照,观察乌骨鸡活性肽对非酶糖基化反应的影响.通过测定预定时间体外非酶糖基化体系的吸光度和荧光值计算乌骨鸡活性肽对非酶糖基化反应的抑制率和对非酶糖基化终产物生成的抑制率.结果表明乌骨鸡活性肽Ⅱ对体外非酶糖基化反应和非酶糖基化终产物的生成均具有较强的抑制作用.     

Charge state effect on the K-shell ionization of iron by xenon ions near the Bohr velocity

Fe K-shell ionization cross sections induced by 2.4–6.0 MeV Xe20+are measured and compared with different binaryencounter-approximation(BEA)models.The results indicate that the BEA model corrected both by the Coulomb repulsion and by the effective nuclear charge(Zeff)agrees well with the experimental data.Comparison of Fe K-shell X-ray emission induced by 5 MeV xenon ions with different initial charge states(20+,22+,26+,30+)verifies the applicability of the effective nuclear charge(Zeff)correction for the BEA model.It is found that Zeffcorrection is reasonable to describe direct ionization induced by xenon ions with no initial M-shell vacancies.However,when the M shell is opened,the Zeffcorrected BEA model is unable to explain the inner-shell ionization,and the electron transfer by molecular-orbital promotion should be considered.     

克尔效应导致的鬼像位置移动

在近轴条件下,利用矩阵光学的方法研究了高功率高斯光束通过不同光学元件时,克尔效应导致的介质折射率的变化对鬼像位置的影响.计算了单个双凸透镜,单个双凹透镜以及4F系统中反射光线形成的低阶鬼像的位置移动,并将鬼像位置移动的规律表示为入射光束束腰和峰值光强的函数.     

Vortex lattice mobility and effective pinning potentials in the peak effect region in YBCO crystals

The peak effect (PE) in the critical current density in both low and high temperature superconductors has been the subject of a large amount of experimental and theoretical work in the last few/several years. In the case of YBCO, crucial discussions describing a dynamic or a static picture are not settled. In that region of field and temperature the mobility of the vortex lattice (VL) is found to be dependent on the dynamical history. Recently we reported evidence that the VL reorganizes and accesses to robust VL configurations (VLCs) with different effective pinning potential wells arising in response to different system histories. One of the keys to understand the nature of the PE is to investigate the VL behavior in the vicinity of the various VLCs in the region of the PE. The stability of these VLCs was investigated and it was found that they have distinct characteristic relaxation times, which may be related to elastic or plastic creep processes. In this paper we review some of these results and propose a scenario to describe the PE in YBCO crystals.     

利用模拟方法研究RFQ加速器中正、负离子束同时加速的动力学问题

在以时间为自变量的PARMTEQ程序的基础上,添加了另一带相反电荷的束流进行动力学计算,同时考虑了正、负离子束加速的空间电荷效应和束团间的作用.并针对特定结构参数的RFQ加速器,给出了双束加速的动力学模拟过程和结果.模拟计算的目的在于研究正、负离子束在RFQ加速结构中同时加速所引起的动力学问题.结果表明,正、负离子束同时加速有助于克服径向空间电荷效应,但在流强较大时,双束加速时,将会在纵向出现明显的异性电荷之间的“捕捉”(trap)现象,从而导致纵向粒子损失数目的增加.因此,为实现双束加速,必须专门重新设计RFQ加速器,使其传输效率高于单束,才能体现出双束加速的优越性     

Erratum to "Quantum compact model for thin-body double-gate Schottky barrier MOSFETs"

<正>The statement for the third paragraph of the right column of page 3079 (Chinese Physics B, 2008, Vol. 17,No. 8, pp. 3077-3082 )[1]is inappropriate. This paragraph should be restated as follows.     

丝氨酸异构体的电子-分子形状共振态及其解离动力学理论研究

Shape resonances of electron-molecule system formed in the low-energy electron attachment to four low-lying conformers of serine (serine 1, serine 2, serine 3, and serine 4) in gas phase are investigated using the quantum scattering method with the non-empirical model potentials in single-center expansion. In the attachment energy range of 0-10 eV, three shape resonances for serine 1, serine 2, and serine 4 and four shape resonances for serine 3 are predicted. The one-dimensional potential energy curves of the temporary negative ions of electron-serine are calculated to explore the correlations between the shape resonance and the bond cleavage. The bond-cleavage selectivity of the different resonant states for a certain conformer is demonstrated, and the recent experimental results about the dissociative electron attachment to serine are interpreted on the basis of present calculations.     

变分原理分析开裂简支箱梁剪力滞效应

变分原理通常应用于箱形截面梁剪力滞效应弹性分析,本文基于换算截面法,运用变分原理推导了预应力混凝土简支箱梁均布荷载作用、钢筋混凝土简支箱梁集中荷载作用的剪力滞系数计算公式,考虑了混凝土开裂对箱梁剪力滞效应的影响,并与试验结果和规范方法进行了对比分析。变分原理分析开裂混凝土箱梁剪力滞效应方法力学概念明确,是其弹性分析适用范围的拓展,亦可推广应用到混凝土连续箱梁开裂后的剪力滞效应分析,具有广阔的应用前景。     

利用B-splines特性计算PbS量子点中的激子基态能量的量子尺寸效应

利用B-splines特性构建量子点中激子的波函数,计算PbS量子点中激子的基态能量E_g的量子尺寸效应,并将计算结果与实验结果及其他理论计算结果进行比较;利用B-splines技术计算的激子的基态能量在整个区域与实验完全符合,同时计算了有效质量和势垒高度对基态能量E_g的量子尺寸效应的影响.     

The Potential Antidepressant Action of Duloxetine Co-Administered with the TAAR1 Receptor Agonist SEP-363856 in Mice

Here, we explored the possible interaction between duloxetine and SEP-363856 (SEP-856) in depression-related reactions. The results showed that oral administration of duloxetine showed powerful antidepressant-like effects in both the forced swimming test (FST) and the suspension tail test (TST). SEP-856 orally administered alone also exerted an antidepressant-like effect in FST and TST, especially at doses of 0.3, 1, and 10 mg/kg. In addition, duloxetine (15 mg/kg) and SEP-856 (15 mg/kg) both showed antidepressant-like effects in the sucrose preference test (SPT). Most importantly, in the above experiments, compared with duloxetine alone, the simultaneous use of duloxetine and SEP-856 caused a more significant antidepressant-like effect. It is worth noting that doses of drug combination in FST and TST did not change the motor activities of mice in the open-field test (OFT). Thus, duloxetine and SEP-856 seem to play a synergistic role in regulating depression-related behaviors and might be beneficial for refractory depression.