新型胃动力药盐酸伊托必利的结构分析

本文以ＵＶ、ＦＴＩＲ、＾１Ｈ－ＮＭＲ、＾１３Ｃ－ＮＭＲ、ＦＡＢＭＳ等现代分析手段，对国内试制的新型胃动力药盐酸伊托必利的化学结构进行了分析鉴定。根据谱带与结构的对应关系，确证其结构与国外已报道的结构一致并对上述各种谱的谱带进行了全面的归属     

Configurational assignment in alkyl‐branched sugars via the geminal C,H coupling constants

The measurement of the magnitude and sign of ²J(C,H) couplings offers a reliable way to determine the absolute configuration at a carbon center in a fixed cyclic system. A decrease of the dihedral angle ? in the O—C_A—C_B—H fragment always leads to a change of the ²J(C_A,H_B) coupling to more negative values, independent of the type and position of substituents at the two carbon centers. The orientations of the two substituents at C‐3 of the epimeric pair 1 and 2 were determined unambiguously through the measurement of the geminal coupling constants between C‐3 and the hydrogen atoms at C‐2 and C‐4. In particular, ²J(C‐3,H‐2ax) with ?1.5 Hz, ? = 174° in 1 and ?6.6 Hz, ? = 47° in 2 , and ²J(C‐3,H‐4) with +1.5 Hz, ? = 175° in 1 and ?4.7 Hz, ? = 49° in 2 showed the greatest differences between the two epimers. Both couplings therefore allow the determination of the absolute configuration at C‐3. It should be noted, however, that the size of the coupling constants can be different for dihedral angles of nearly identical size, when there are different numbers of electronegative substituents on the two coupling pathways, i.e. no O‐substituent at C‐2, but one axial O‐substituent at C‐4. It becomes clear that it is not sufficient to measure the magnitude of ²J coupling constants only, but that the sign of the geminal coupling is needed to identify the absolute configuration at a chiral center. The coupling of C‐3 with H‐2eq is not useful for the determination of the configuration at C‐3, as the similarity of the dihedral angles ? (O—C‐3—C‐2—H‐2eq) (57° in 1 and 70° in 2 ) leads to identical coupling constants (?6.1 Hz) for both epimers. Copyright © 2003 John Wiley & Sons, Ltd.     

产销平衡运输问题的表上作业法解法的一个注记

本文给出了用表上作业法求解产销平衡运输问题当出现退化时在相应空格填“O”的更为明确的规则，利用该规则可以避免可能存在的多余计算。本文还给出了用改进后的表上作业法求解指派问题的方法和步骤，该方法与求解指派问题的常用方法“匈牙利法”相比，具有手工计算更为简便的优点。     

广义线性系统基于PI观测器鲁棒极点配置分离原理

对广义线性系统提出了基于全维比例-积分观测器的控制系统设计的鲁棒极点配置分离原理.基于矩阵灵敏度理论证明了如下事实：与状态反馈系统相同的闭环系统极点具有和状态反馈系统极点相同的极点灵敏度,与观测器系统相同的闭环系统.极点具有和观测器系统极点相同的极点灵敏度.于是基于全维PI观测器的状态反馈控制器的具有最小灵敏度的鲁棒极点配置可以通过求解两个分开的鲁棒状态反馈极点配置问题实现.     

线性系统的输出反馈特征结构配置——具有不可控不可观模态的情形

本文考虑具有不可控不可观模态的线性系统的输出反馈特征结构配置问题。根据文中给出的矩阵方程AV＋BW＝VF的一种显式参数解，得到了线性系统的输出反馈特征结构配置的一种参数化方法，本文没有对系统附加能控能观条件，在[AB]能控的条件下，本文得到的矩阵方程的解是文[5]中定理2的结果，在[AB]能控且[AC]能观的条件下，本文得到的输出反馈特征结构配置方法是文[6]在系统为定常时算法Ⅱ的结果。     

湖北绿茶中两种新的没食子酸类衍生物的结构鉴定

用2D NMR技术研究了从绿茶中分离得到的2种新的没食子酸类衍生物,对其¹H和¹³C NMR谱线作了全归属.     

关于几类图的L(3,2,1)-标号问题

图G的L(2，1)-标号是一个从顶点集V(G)到非负整数集的函数f(x)，使得若d(z，y)=1则|f(x)-f(y)|≥2；若d(x，y)=2，则|f(x)-f(y)|≥1。图G的L(2，1)-标号数是λ(G)使得G有的max|f(v)：v∈V(G)|=κ的L(2，1)-标号中的最小数κ。本将L(2，1)-标号问题推广到更一般的情形即L(3，2，1)标号问题，并得到了平面三角剖分图、立体四面体剖分图的λ3(G)的上界。     

求解指派问题的一个算法

为了便于建立与指派问题有关的决策支持系统，本给出了一个求解指派问题的数值算法，证明了算法的理论依据。该算法能求得问题的最优解，并具有易于编程实现、收敛性好等优点，大量数值实验表明该算法非常实用有效。     

Transportation problems which can be solved by the use of hirsch-paths for the dual problems

Balinski uses his signature method for the proof of the Hirsch-conjecture for dual transportation polyhedra to obtain an efficient algorithm for the assignment problem. We will show how to extend this method to other primal transportation problems, including transportation problems with unit demands. We then prove that Balinski's assignment algorithm is equivalent, cycle by cycle, to that of Hung and Rom. We demonstrate that, under some assumptions for our probability model, a modification of the latter algorithm has an average complexity of O(n ²logn) and present some computational results confirming this. We also present results that indicate that this modification compares favorably with Balinski's algorithm and other codes. Research of both authors supported, in part, by grants of the Alexander von Humboldt-Stiftung. Supported, in part, by NSF grant DMS-8504050.