首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   2077篇
  免费   132篇
  国内免费   334篇
化学   1821篇
晶体学   5篇
力学   90篇
综合类   18篇
数学   42篇
物理学   567篇
  2024年   2篇
  2023年   12篇
  2022年   25篇
  2021年   41篇
  2020年   49篇
  2019年   49篇
  2018年   50篇
  2017年   57篇
  2016年   59篇
  2015年   72篇
  2014年   111篇
  2013年   273篇
  2012年   79篇
  2011年   134篇
  2010年   93篇
  2009年   100篇
  2008年   118篇
  2007年   153篇
  2006年   119篇
  2005年   110篇
  2004年   106篇
  2003年   116篇
  2002年   94篇
  2001年   80篇
  2000年   71篇
  1999年   56篇
  1998年   58篇
  1997年   42篇
  1996年   32篇
  1995年   24篇
  1994年   32篇
  1993年   33篇
  1992年   21篇
  1991年   11篇
  1990年   9篇
  1989年   9篇
  1988年   9篇
  1987年   4篇
  1986年   6篇
  1985年   6篇
  1984年   3篇
  1983年   2篇
  1982年   1篇
  1981年   1篇
  1980年   2篇
  1978年   1篇
  1973年   2篇
  1972年   1篇
  1971年   1篇
  1970年   4篇
排序方式: 共有2543条查询结果,搜索用时 31 毫秒
141.
The synthesis of novel substituted 3-p-nitro-phenyliminocoumarins and corresponding N-ureaiminocoumarins is described. The condensation of these materials with oxalyl chloride leads to the corresponding N-parabanic iminocoumarins, which have not previously been described, in moderate or good yields and high selectivity. The structures were characterized by Fourier transform infrared, 1H and 13C NMR, and elemental analysis.

Additional information

ACKNOWLEDGMENTS

The authors acknowledge the Ministry of Higher Education, Scientific Research, and Technology in Tunisia for their financial support. They also thank Pr. Rachid El Gharbi for his useful discussions about this work.  相似文献   
142.
The reaction of 3-acylsubstituted 2H-1-benzo-pyran-2-ones 1, 5 and 11a-c with acid anhydrides in the presence of potassium fluoride (KF)/molecular sieves 4A gives the 4-(2-oxoalkyl)-2-oxochromans 2, 6 and 12a-c as the main products. Also the 3-carboxylic acid derivatives, such as esters and N,N-dialkylamides, of 2H-1-benzopyran-2-one (11d-g) react with isobutyric acid anhydride in the presence of KF/molecular sieves 4A to give the corresponding 2-oxochroman-4-acetic acid derivatives.  相似文献   
143.
A convenient three‐step route toward a functionalized pyrrole building block for novel anti‐inflammatory agents is reported. In contrast to previous strategies, the present approach focuses on inexpensive starting materials and application on a multigram scale. A high degree of functional diversity is demonstrated in various derivatives, and the scope and limitations of this route are discussed. Complementary to the described tetrasubstituted pyrroles, a novel ring‐closure protocol based on the Feist–Benary condensation affords trisubstituted analogues.  相似文献   
144.
A series of chalcone derivatives (3a–k) were prepared via the reaction of cis-bicyclo[3.2.0]hept-2-en-6-one (1) with the respective arylaldehydes (2a–k) and were then characterized by Fourier transform infrared (FT-IR), 1H NMR, 13C NMR, and elemental analyses.  相似文献   
145.
A simple, mild, and ecofriendly method has been developed for the synthesis of 3-vinylchromones from 4-oxo-4H-1-benzopyran-3-carboxaldehyde (3-formylchromone) by simple Knoevenagel condensation with various active methylene compounds (AMC) in aqueous micellar media in the presence of catalytic amounts of cetyl trimethylammonium bromide (CTAB) and 1,4-diazabicyclo[2.2.2]octane (DABCO). In the case of malonic acid as AMC, the reaction resulted in formation of only Doebner decarboxylated products under the standard reaction condition. It has been also observed that 3-formylchromone derivatives primarily undergo tandem Knoevenagel and Michael reactions in the presence of > 2 equiv. of ethyl acetoacetate to produce benzophenone derivatives, by opening of pyran ring, as the sole product in good yields.  相似文献   
146.
《合成通讯》2013,43(24):4521-4529
Abstract

The Knoevenagel condensation of aromatic aldehydes with (2‐thio)barbituric acid proceeded efficiently in reusable ionic liquids, EAN, BmimBF4, and BmimPF6 at room temperature in the absence of any catalyst with high yields.  相似文献   
147.
5-Allyl-7,7-difluoro-2-(2,4-difluorophenyl)-6-(4-methoxyphenyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-3-amine represents a fluorinated heterocyclic scaffold, potentially attractive. It was synthesized via Michael addition, Mannich reaction of the difluorinated ethyl bromoacetate with a benzotriazole derivative, followed by a Dieckmann condensation. Starting from simple materials, this efficient route which gives access to novel functionalized N-(5-allyl-7,7-dihalo)-4,5,6,7-tetrahydro-2H-indazol-3-yl)-carboxymides, was explored and adapted for parallel synthesis, resulting in a compound library.  相似文献   
148.
用FeCl3·6H2O催化3-甲基环己酮与丙酮酸乙酯交叉羟醛缩合,制得2-(2-氧代-4-甲基环己叉基)丙酸乙酯和7a-羟基薄荷内酯,皂化后用硼氢化钠还原、酸化制得(±)-薄荷内酯,产率为51%。考察了3-甲基环己酮的烯醇式异构化的位置选择性和粗产物中(±)-薄荷内酯与(±)-异薄荷内酯异构体的比例。  相似文献   
149.
《Tetrahedron letters》2014,55(52):7233-7235
The α-alkylation of ketones with primary alcohols was realized by CC cross-coupling with iridium–CNP complexes as catalyst. This reaction proceeds via dehydrogenation reactions, aldol condensation, and hydrogenation using the borrowed hydrogen atoms from alcohols. The pyridyl methanols and other heterocyclic substituted methanols, especially alkyl alcohols, were also suitable for this transformation.  相似文献   
150.
A new method was adopted for the synthesis of benzo[b]carbazoles by Claisen condensation followed by Fischer indole cyclization. Newly synthesized benzo[b]carbazoles were treated with ethanol amine in the presence of polyphosphoric acid which leads to the formation of pyrazino carbazoles. All the synthesized compounds were characterized by all spectral means.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号