DNA damage induced by laser-hematoporphyrin derivative

Irradiation caused DNA single-strand breaks in S180 cells in the presence oflaser-hematoporphyrin derivative(HPD).The number of single strand breaks was 3.69 ×10~(10)break dolton~(-1).The analysis of base composition of DNA showed that the effect of laser-HPDirradiation on guanine was the highest,being 5-12 times as high as those of the three others(adenine,cytosine and thymine).It was different from the nature of DNA damage caused by γ-ray irradiation.     

Numerical analysis of the developing fluid flow in a circular duct rotating steadily about a parallel axis

A numerical analysis of the flow pattern in the inlet region of a circular pipe rotating steadily about an axis parallel to its own is presented. Both finite cell and finite element methods are used to analyse the problem and they give qualitatively similar results which show that a swirling fluid motion is induced in the pipe inlet region. The analyses show that the direction of swirl is opposite to that of the pipe rotation when viewed along the flow axis and that its magnitude depends on the speed of pipe rotation and throughflow Reynolds number. Neither numerical analysis predicts the marked upturn in friction factor (or pressure drop) which has been observed experimentally. However, a dependence on the pipe inlet boundary conditions is demonstrated.     

Femoral head avascular necrosis in sickle cell anemia: MR characteristics

Since considerable expansion of hematopoietic marrow occurs in patients with sickle cell anemia (SCA), magnetic resonance images of 20 hips in 10 patients with known homozygous SCA were reviewed to determine a) if low signal hematopoietic marrow extended into the femoral capital epiphysis and b) if the MR characteristics of avascular necrosis (AVN) differed depending on the type of epiphyseal marrow. Our results revealed variable epiphyseal marrow type; mixed (fatty and hematopoietic) marrow (42%), fatty marrow (32%), hematopoietic marrow (16%) and hemosiderotic marrow (10%). AVN occurred irrespective of the underlying marrow. Segmental areas of low signal intensity in variable shapes (ring, band, crescent or large homogeneous area) was the most consistent MR manifestation of AVN in SCA. A low signal intensity peripheral rim surrounding a central zone, isointense with epiphyseal marrow on T₁ and T₂ weighted images, was most frequently observed similar to that described in patients without hemoglobinopathy. The notable difference, however, was of segmental areas within the same femoral head that demonstrated variable central zone signal on T₂ weighted images. Further, while an increase in hip joint fluid is commonly seen with both early and advanced AVN in patients without hemoglobinopathy; it was increased in only one hip in patients with SCA. The observed differences in MR characteristics may be due to different pathophysiology of AVN in patients with SCA.     

The L2-optimal cell width for the histogram

We give the value of the cell width which minimizes the integrated mean squared error of the histogram estimate of a multivariate density.     

β-BaB2O4晶体高压相变的X光衍射研究

 我们用金刚石压砧装置（DAC）高压X射线粉末衍射照相方法，研究了β-BaB₂O₄晶体的相变。压力从0.1 MPa逐步加至17.6 GPa，发现BBO由室温下的六方相经历了若干次相变后，当压力加至11.5 GPa时，转变为无定形相。在11.5 GPa压力前的相变是可逆的，一旦进入无定形相，则相变是不可逆的。     

固体聚合物电解质燃料电池的研究

报道了固体聚合物电解质燃料电池的电极制备方法和温度，压力以及阴极气量对电池性能的影响。     

Micro-scale mechanics of the surface- nanocrystalline Al-alloy material

Recentresearchesshowthatthehighstrengthnano-structuredmaterialscanbefabricatedbyusingsomeadvancedtechniques,andthemechanicalbehavioroftheconventionalmaterialscanbeimprovedbyusingasurface-nanocrystallinetechnique.Forexample,byusingthesevereplasticdeformation(SPD)method,onecanfabricatethenanocrystallinematerials[15].TheadoptedSPDmethodsmainlyincludethelargetorsionmethod[1],thelargepressingmethod[4]andtheultrasonicshotpeening(USP)method[5],etc.Theconstructionfeaturesofboththenano-structuredbl…     

Effect of quasi-periodic gravitational modulation on the convective instability in Hele-Shaw cell

The aim of the present paper is to examine the effect of a quasi-periodic gravitational modulation on the onset of convective instability in Hele-Shaw cell. The quasi-periodic modulation considered here consists in a modulation having two incommensurate frequencies. This study is an extension of a previous work by Aniss et al. [Asymptotic study of the convective parametric instability in Hele-Shaw cell, Phys. Fluids 12 (2) (2000) 262-268] in which only a periodic gravitational modulation was considered. We have shown that for Pr=O(1) or Pr?1, the gravitational modulation has no effect on the convective threshold as expected. However, for Pr=O(ε²), it turns out that a modulation with two incommensurate frequencies has a stabilizing or a destabilizing effect strongly depending on the frequencies ratio.     

超短超强激光与稀薄等离子体相互作用的数值研究

用一维粒子模拟方法（Ｐａｒｔｉｃｌｅ－ｉｎ－Ｃｅｌｌ）数值研究了超短超强激光（Ｉλ＾２〉１０＾１８Ｗ．μｍ＾２／ｃｍ＾２）与稀薄等离子体的相互作用过程，结果表明，超短超强激光与稀薄等相互作用后，在等离子体中激发起尾波和拉曼（Ｒａｍａｎ）波，它们的波长和频率的值与解析解符合得很好；同时在尾波的作用下，等离子体的部分电子被加速的很高的速度，甚至接近光速。     

TRANSFORMATION OF CULTURED HUMAN FETAL GASTRIC FIBROBLASTS WITH PHYSICO-CHEMICAL AGENTS

Treatment of early passage human fetal gastric fibrohlasts with ultraviolet (UV) light and the chemical carcinogen ethyl nitrosourea (ENU) in succession resulted in an immortally growing cell line, named GTS 8502. The cells of this line display typical transformation characteristics, such as irregularly shaped nuclei, heteroploidization of karyotype and frequent appearance of heteromorphic chromosomes, the enhanced volume ratio of nucleus to cytoplasm, multinucleoli, appearance of microvilli on the surface of the cells and agglutination reaction to lectin concanavalin A. The transformants have high growing and mitotic indices and the ability of focus-formation on monolayers and anchorage independent growth in soft agar medium. Moreover, these cells induced turnouts in nude mice or in immunosuppressed new-born rats through heterotransplantation. The results of various methods including electromicroscopy and histochemical analyses indicate that GTS 8502 cells are of fibroblast origin.Our results thus indi