Catalytic oxidative cleavage of olefins by RuO4 organic solvent-free under ultrasonic irradiation

All the works reported about oxidative cleavage of olefins by the RuCl₃/NaIO₄ catalytic system have been performed in biphasic water/organic solvent(s). The first organic solvent-free oxidation of CC double bond by 2% RuCl₃/4.1 equiv NaIO₄/H₂O is described here using both the emulsifier Aliquat® 336 and 20 kHz ultrasonic irradiation.     

Mechanism of W(CO)6 sonolysis in diphenylmethane

The present work analyses the mechanism of W₂C/C nanocomposite formation during sonolysis of W(CO)₆ in diphenylmethane (DPhM) solutions. Carbon supported WC_x nanoparticles attract much interest as an alternative fuel cell electrocatalysts. Sonolysis of neat DPhM under the effect of 20 kHz power ultrasound in argon at 80 °C yields a sonopolymer as a solid product and acetylene, hydrogen, methane, diacetylene and benzene as gaseous products. Diacetylene is formed due to the secondary sonochemical dimerisation of acetylene obtained at the primary stage of DPhM sonolysis. FTIR and μ-Raman studies show that the sonopolymer consists of a mixture of some polymeric partially oxidized aromatic species, and disordered carbon. Sonolysis of W(CO)₆ in diphenylmethane solutions follows the first order kinetics. This process yields monodispersed 2-3 nm X-ray amorphous WC_x nanoparticles embedded in amorphous sonopolymer. The annealing of air sensitive as-prepared solids in an inert atmosphere at 600 °C causes formation of stable W₂C/C nanocomposite with W₂C average particle size in the range of 4-7 nm and hexagonal carbon fine particles with the average size of 30-40 nm. Kinetic study revealed that tungsten carbide is formed inside the cavitation bubble due to the reaction of tungsten nanoparticles originated from primary sonolysis of W(CO)₆ with acetylene produced as a result of diphenylmethane sonochemical degradation.     

The uses of ultrasound in food technology

The same physical and mechanical effects which have been utilised in sonochemistry, i.e. strong shear forces, particle fragmentation, increased mass and heat transfer, nucleation of seedling, have been applied to food processing. Examples are quoted from various applications where power ultrasound has been used to influence the development of living cells, improve sterilisation and effect enzyme activity. Typically ultrasound can be used as a processing aid in extraction, crystallisation, freezing, emulsification, filtration and drying.     

Sonochemical fabrication of edible fragrant antimicrobial nano coating on textiles and polypropylene cups

We report on a simple and effective ultrasound-assisted deposition of vanillin nanoparticles (∼50 nm in size), raspberry ketone (RK) nanoparticles (∼40 nm in size) and camphor nanoparticles (width ∼30 nm, length ∼40 nm in size) on textiles and on polypropylene surfaces. The excellent antibacterial and antifungal activity of the fragrant coatings on cotton bandages, and polypropylene surface against Escherichia coli (E. coli), Salmonella paratyphi A (S. paratyphi A) and the yeast Candida albicans (C. albicans) cultures was demonstrated. It is worth pointing out that these fragrant materials are edible, making them very useful for packaging. The mechanism of the edible fragrant coating formation and adhesion to the textile was discussed, and finally an up-scaling of the sonochemical process for textile coating was carried out.     

A phenomenological investigation into the opposing effects of fluid flow on sonochemical activity at different frequency and power settings. 2. Fluid circulation at high frequencies

Sonochemical activity is dependent on flow patterns within the reactor and either no affect or a decrease in activity was observed at 376, 995, and 1179 kHz from overhead stirring. The interaction of fluid flow with ultrasound was further investigated in this study with circulatory flow. The effect of fluid circulation on radical production was investigated at two circulation speeds, with and without surface stabilisation. The sonochemical activity was determined by the yield of hydrogen peroxide, measured by iodide dosimetry. The sonochemically active region was pictured using sonochemiluminescence imaging and the flow fields were visualised with dyed flow videos. At 376 and 995 kHz, an increase in sonochemical activity was observed with the slower flow rate; however at 1179 kHz, the sonochemical activity was either not affected or decreased. The observed changes in sonochemical activity were attributed to an increase in asymmetry of the bubble collapse brought about by fluid motion.     

Radical production inside an acoustically driven microbubble

The chemical production of radicals inside acoustically driven bubbles is determined by the local temperature inside the bubbles and by their composition at collapse. By means of a previously validated ordinary differential equations (ODE) model [L. Stricker, A. Prosperetti, D. Lohse, Validation of an approximate model for the thermal behavior in acoustically driven bubbles, J. Acoust. Soc. Am. 130 (5) (2011) 3243–3251], based on boundary layer assumption for mass and heat transport, we study the influence of different parameters on the radical production. We perform different simulations by changing the driving frequency and pressure, the temperature of the surrounding liquid and the composition of the gas inside the bubbles. In agreement with the experimental conditions of new generation sonochemical reactors, where the bubbles undergo transient cavitation oscillations [D. F. Rivas, L. Stricker, A. Zijlstra, H. Gardeniers, D. Lohse, A. Prosperetti, Ultrasound artificially nucleated bubbles and their sonochemical radical production, Ultrason. Sonochem. 20 (1) (2013) 510–524], we mainly concentrate on the initial chemical transient and we suggest optimal working ranges for technological applications. The importance of the chemical composition at collapse is reflected in the model, including the role of entrapped water vapor. We in particular study the exothermal reactions taking place in H₂ and O₂ mixtures. At the exact stoichiometric mixture 2:1 the highest internal bubble temperatures are achieved.     

Acoustic cavitation structures produced by artificial implants of nuclei

High-density controllable bubble structures are produced in the vicinity of radiating surface by artificially implant nuclei. Two kinds of typical cavitation structures produced by artificially implant nuclei are investigated. The focusing action and the physical origin of jet-induced cone-like bubble structure are analyzed. The sonochemical activity of cavitation structures is measured by using the standard method of potassium iodide dosimetry. The controllability of cavitation bubble cluster in the acoustic field is also discussed in this work.     

Preparation of novel magnetic fluorescent nanospheres by sonochemical method

This study focuses on the preparation and characterization of magnetic fluorescent nanospheres (MFNs). MFNs are prepared using a sonochemical method in the presence of hydrophobic Fe₃O₄ nanopaticles, and then the nanospheres are modified with Rhodamine B through an electrostatic interaction. The properties of MFNs are characterized using transmission electron microscopy, Fourier-transform infrared, thermogravimetric analysis, vibration sample magnetometry, and fluorescence emission spectrum. The results indicate that the superparamagnetic nanospheres have a particle size of 160 nm, high saturation magnetization of 54 emu/g, and significant fluorescence. MFNs possess potential in medical imaging, drug targeting, and catalysis. The possible formation mechanism of MFNs is discussed.     

Antibody modified Bovine Serum Albumin microspheres for targeted delivery of anticancer agent Gemcitabine

Inhibition of the EGFR signaling pathway is one of the attractive therapeutic targets for pancreatic cancer as recent studies demonstrated that EGFR is over‐expressed in pancreatic cancer. In this article we have demonstrated the design of targeted drug delivery system containing Bovine Serum Albumin (BSA) microspheres as delivery vehicle, gemcitabine as anticancer drug and anti‐EGFR (epidermal growth factor receptor) monoclonal antibody as targeting agent. The conjugated BSA microspheres were characterized by several physico‐chemical techniques such as scanning electron microscope, optical microscopy, fluorescent microscopy etc. Administration of these BSA microspheres containing gemcitabine and anti‐EGFR (BSA‐Gem‐EGFR) shows significant inhibition of pancreatic cancer cells (AsPC1) compared to the cells treated with only BSA microspheres, BSA with gemcitabine (BSA‐Gem), and free gemcitabine. This strategy could be used as a generalized approach for the treatment of pancreatic cancer along with other cancers which overexpress EGFR on cell surface. Copyright © 2012 John Wiley & Sons, Ltd.     

Ultrasonically assisted surface modified CeO2 nanospindle catalysts for conversion of CO2 and methanol to DMC

This study developed a facile and effective approach to engineer the surface properties of cerium oxide (CeO₂) nanospindle catalysts for the direct synthesis of dimethyl carbonate (DMC) from CO₂ and methanol. CeO₂ nanospindles were first prepared by a simple precipitation method followed by wet chemical redox etching with sodium borohydride (NaBH₄) under high intensity ultrasonication (ultrasonic horn, 20 kHz, 150 W/cm²). The ultrasonically assisted surface modification of the CeO₂ nanospindles in NaBH₄ led to particle collisions and surface reduction that resulted in an increase in the number of surface-active sites of exposed Ce³⁺ and oxygen vacancies. The surface modified CeO₂ nanospindles showed an improvement of catalytic activity for DMC formation, yielding 17.90 mmol·g_cat⁻¹ with 100 % DMC selectivity. This study offers a simple and effective method to modify a CeO₂ surface, and it can further be applied for other chemical activities.