Assessing outcomes for dysphonic patients

This study was designed to evaluate a disease-specific outcome measure for patients with selected voice disorders and to relate this instrument to a standardized quality of life measurement. In addition, the study attempts to document the degree of handicap for dysphonia patients globally, between different vocal pathologies, and in comparison to other chronic diseases. In this prospective, observational study, 260 adult patients evaluated for alterations of voice completed a general quality of life measure (the Medical Outcomes Trust Short Form 36-Item[SF-36]) and a voice-specific instrument (Voice Handicap Index [VHI]) pretreatment.

The highest correlation was between the social functioning score of the SF-36and the total score of the VHI and the physical, emotional, and functional subscales (p < 0.001) of the VHI. Significant correlation was also obtained for the SF-36 domains mental health (p < 0.01), general health (p < 0.01), and role functioning emotional (p < 0.017) with the three VHI domains and the total VHI score. Patients had significantly lower scores than the general U.S. population in five of the eight domains of SF-36. Patients with vocal fold paralysis had the highest level of pretreatment disability as measured on both the VHI and SF-36 among voice patients. The patients with dysphonia had a lower level of physical functioning than the patients with chronic sinusitis (p < 0.01), reflecting a greater handicap. In addition, the dysphonia group had lower levels of social functioning than the angina (p < 0.01) and sciatica (p < 0.01) groups and a lower score for mental health than the angina group (p < 0.01).

The SF-36 correlates with the VHI in the domains of social functioning,mental health, and role functioning emotional. The baseline handicap for voice disorders represents a significant disability even in comparison to conditions such as angina pectoris, sciatica, and chronic sinusitis.     

求解stokes问题的一个新的非协调混合元格式

构造一个新的非协调混合元格式求解stokes问题,证明了该元满足B-B条件,并且有2阶收敛速度.     

The Order Completion Method for Systems of Nonlinear PDEs: Pseudo-topological Perspectives

By setting up appropriate uniform convergence structures, we are able to reformulate the Order Completion Method of Oberguggenberger and Rosinger in a setting that more closely resembles the usual topological constructions for solving PDEs. As an application, we obtain existence and uniqueness results for the solutions of arbitrary continuous, nonlinear PDEs.      

Charge-conserving electron density averaging for a set of nuclear configurations

The Löwdin-Inverse Löwdin Transformation (LILT) technique combined with the Diophantine Density Matrix Purification (DDMP) method is suggested for a charge-preserving density averaging approach for a range of nuclear configurations.     

Quadratic spline-on-spline

Recently Dolezal and Tewarson [2], and Papamichael and Soares [3] have considered the cubic spline-on-spline for the purpose of the approximating the derivatives y⁽²⁾,y⁽³⁾, and y⁽⁴⁾. In this paper their ideas have been extended and the quadratic spline-on-spline has been established for the same purpose. This technique yields better results than the traditional process using a single quadratic spline.     

A mixed algorithm for the calculation of rapidly varying fluid flows: The impulsively started circular cylinder

A mixed discrete Fourier transform-Finite difference algorithm is developed and used for the calculation of rapidly changing viscous fluid flows past a circular cylinder. The numerical approach has been designed to overcome certain difficulties arising for high Reynolds number simulations. The foremost advantage of the technique lies in its fast calculations of the convolution sums portraying the convective terms of the governing equations. Third-order spatial discretizations and fourth-order time marching are implemented. New schemes are proposed for the boundary conditions at the solid wall and at large distances. The techniques are tested on a case study with other schemes (summarized by Roache¹) in order to obtain an optimal choice. Definite indications on the stability and accuracy of boundary condition schemes are achieved. Support for the statement of dominant importance of boundary conditions is also given. A comparison of computational results with experimental data is presented for the case study of the flow past an impulsively started cylinder at Reynolds number 20. The time development of the symmetrical zone of recirculation, which is formed at an early stage of the flow, has been studied for 300 ≤ Re ≤ 9500 by means of the proposed algorithm. Computational results, comparisons with experimental data² and discussion of upper limits of validity of the procedure will be presented in a companion paper.     

关于n阶微分方程边值问题（Ⅲ）——奇摄动的渐近展开

本文研究n阶非线性过值问题(NB)的奇异摄动。在较一般的条件下,应用高阶微分不等式理论证明了摄动解的存在性,并给出了摄动解直到n阶导函数的一致有效渐近展开式,推广和改进了已有的结果。     

The range of the p-Laplacian

We prove that for λ ≥ 0, p ≥ 3, there exists an open ball B L²(0,1) such that the problem

− (|u′|^p−2 u′)′ − λ|u|^p−2u = f, in (0,1)

, subject to certain separated boundary conditions on (0,1), has a solution for f B.     

An approach to high-speed micro-HPLC

The possibility of high-speed micro-HPLC has been investigated using a short micro-column (35 mm × 0.5 mm i.d.) packed with 3 μm ODS particle. The results indicate that this approach has considerable potential for good separations with short analysis time. A typical example shows only three minutes is required with a plate count of 3,800 to separate seven PAHs.     

One- and two-sample match statistics

A mathc statistic considered by Khidr (1981) is interpreted in terms of crossings of the empirical and true distribution functions and a simpler alternate derivation of its distribution provided. This approach can also be used to obtain the distribution of a two-sample match statistic, considered earlier by Takács (1971).