全文获取类型
收费全文 | 953篇 |
免费 | 26篇 |
国内免费 | 96篇 |
专业分类
化学 | 982篇 |
晶体学 | 6篇 |
力学 | 1篇 |
综合类 | 8篇 |
物理学 | 78篇 |
出版年
2023年 | 9篇 |
2022年 | 24篇 |
2021年 | 15篇 |
2020年 | 14篇 |
2019年 | 15篇 |
2018年 | 22篇 |
2017年 | 23篇 |
2016年 | 32篇 |
2015年 | 33篇 |
2014年 | 47篇 |
2013年 | 77篇 |
2012年 | 99篇 |
2011年 | 58篇 |
2010年 | 49篇 |
2009年 | 63篇 |
2008年 | 73篇 |
2007年 | 62篇 |
2006年 | 54篇 |
2005年 | 44篇 |
2004年 | 44篇 |
2003年 | 44篇 |
2002年 | 29篇 |
2001年 | 26篇 |
2000年 | 21篇 |
1999年 | 12篇 |
1998年 | 13篇 |
1997年 | 15篇 |
1996年 | 10篇 |
1995年 | 6篇 |
1994年 | 12篇 |
1993年 | 4篇 |
1992年 | 7篇 |
1990年 | 7篇 |
1989年 | 1篇 |
1988年 | 3篇 |
1986年 | 1篇 |
1985年 | 4篇 |
1984年 | 1篇 |
1978年 | 1篇 |
1977年 | 1篇 |
排序方式: 共有1075条查询结果,搜索用时 15 毫秒
61.
测量并分析了盐酸苯海拉明的红外光谱和拉曼光谱。在Raman光谱中, 1001 cm-1出现一个极强峰, 在1030 cm-1和618 cm-1各有一个中等峰,此外,在红外光谱中, 714 cm-1和757 cm-1附近出现极强的吸收峰,认定这个化合物中存在单取代苯。C-N的对称伸缩振动出现在837 cm-1, 1433 cm-1和1470 cm-1分别为CH2和CH3的变形振动, 在红外光谱中, 1020 cm-1处明显的吸收峰属于C-O-C反对称伸缩振动。此外, 测量得到含量为25 mg苯海拉明药片的拉曼光谱与纯苯海拉明的拉曼峰比较一致, 可作为无损快速检测该药物的手段。 相似文献
62.
将阳极氧化与光还原法结合,在TiO_(2)纳米管阵列(TiO_(2)NTAs)表面修饰Ag纳米粒子,获得一种均匀有序、稳定性高且可循环的TiO_(2)NTAs/Ag活性基底。采用X射线粉末衍射(XRD)、X射线光电子能谱(XPS)、紫外可见漫反射光谱(UV-Vis DRS)、表面增强拉曼散射光谱(SERS)和扫描电子显微镜(SEM)等手段对TiO_(2)NTAs/Ag的组成和结构进行了表征。进一步研究了该TiO_(2)-NTAs/Ag阵列对盐酸四环素(TC-HCl)的SERS响应,结果表明,该复合基底对TC-HCl具有较高的检测灵敏度,在水中检测限可达1×10^(−14) mol/L,而TiO_(2)-NTAs与Ag之间的协同效应对其检测性能的提高起着关键作用。此外,TiO_(2)NTAs/Ag基底在光照下对TC-HCl展示了优异的降解活性,且至少可循环使用8次。表明该TiO_(2)NTAs/Ag基底在环境中有机污染物的SERS检测和降解领域具有潜在的应用前景。 相似文献
63.
Zeid Abdullah Alothman Nausheen Bukhari Sajjad Haider Saikh Mohammad Wabaidur Abdulrahman A. Alwarthan 《Arabian Journal of Chemistry》2010,3(4):251-255
A novel sensitive fluorimetric method was investigated for the assay of fexofenadine hydrochloride (FEX) using silver nanoparticles (NPs) as a fluorescence probe. The NPs, which were prepared by chemical reduction of silver nitrate with sodium borohydride (reducing agent) in aqueous solution (without organic stabilizers) were water soluble, stable and had narrow emission band. The addition of drug to NPs solution caused considerable quenching of the emission band of silver NPs, which was likely due to the complexation of the drug to silver NPs. Under the optimum conditions, the quenched fluorescence (FL) intensity was linear with the concentration of FEX in the range of 1 × 10?7 to 2.5 × 10?5 mol L?1 (0.9985) with a detection limit of 1.2 × 10?8 mol L?1. The quenching mechanism of the studied drug on the emission band of silver NPs was explained by Stern–Volmer law. The developed method was applied to FEX determination in a pharmaceutical formulation (allegra tablets) and biological fluids (human serum and urine). 相似文献
64.
This study describes the application of confocal Raman microscopy to the detection and identification of drugs-of-abuse in situ on undyed natural synthetic fibres, and coloured textile specimens. Raman spectra were obtained from drug particles trapped between the fibres of the specimens. Pure samples of cocaine hydrochloride and N-methyl-3,4-methylenedioxy-amphetamine HCl (MDMA-HCl) were used in this study. Raman spectra were collected from drug particles of an average size in the range 5-15 μm. Despite the presence of spectral bands arising from the natural and synthetic polymer and dyed textiles, the drugs could be identified by their characteristic Raman bands. If necessary, interfering bands could be successfully removed by spectral subtraction. Furthermore, Raman spectra were recorded from drug particles trapped between the fibres of highly fluorescent specimens. Interference from the fibres, including background fluorescence, was overcome by careful focusing of the confocal beam and the resulting spectra allow ready differentiation from interference from the fibres substrate bands. Spectra of several drugs-of-abuse on dyed and undyed clothing substrates were readily obtained within 3 min with little or no sample preparation and with no alteration of the evidential material. 相似文献
65.
DrugFET的研究(Ⅳ).硅钨酸—麻黄碱FET的研制与应用 总被引:5,自引:0,他引:5
将离子敏感场效应晶体管与药物敏感膜相结合研制成一种对盐酸麻黄碱有良好响应的药物敏感场效应晶体管传感器。 相似文献
66.
二价铜、锌离子对盐酸巴马亭与牛血清白蛋白结合反应光谱的影响研究 总被引:9,自引:0,他引:9
The binding of Palmatine hydrochloride to bovine serum albumin (BSA) was studied, in the presence of Cu2+ and Zn2+, with fluorescence spectrum and ultra-violet spectrum. The results show that Cu2+ and Zn2+ don′t influence the first binding constant of Palmatine to BSA and the binding site of it to BSA. But Cu2+ has the fluorescence quenching effect on sensitive fluorescence of medicine binding to BSA. 相似文献
67.
盐酸羟胺的间接分光光度法测定 总被引:2,自引:1,他引:2
拟定了在铁(Ⅲ)—2-[2-(6-甲基苯并噻唑)偶氮]-5-二乙氨基苯甲酸(6MeBTAEB)络合物和十二烷基硫酸钠存在下盐酸羟胺的间接分光光度测定方法,回收试验表明该法准确可靠,方便快捷。同时测定了盐酸羟胺与Fe(Ⅲ)-6_Me_BTAEB络合物的反应比。 相似文献
68.
69.
ALAM Md.Sayem KABIR-UD-DIN 《物理化学学报》2008,24(3):411-415
The effect of electrolytes on the micellar behavior of an amphiphilic drug,chlorpromazine(CPZ)hydroehloride,was studied using cloud point(CP)and dye solubilization techniques.In the presence of KBr,increase because of deprotonation of drug molecules at high pH. The visible absorbance increased(due to dye solubilization)with the increase in pH from 6.5 to 6.9,which indicated micellar growth.At fixed pH(6.7),addition of inorganic salts(KF,KC1,effecfiveness being in the order:F-Na >K ,which Was explained by considering cognizance of their hydrated radii.Compared with anions,their effect was small.Increase in[CPZ]caused micellar growth and hence the CP as well as the visible absorbance increased.The overall behavior Was discussed in terms of electrostatic interactions and micellar growth. 相似文献
70.
The complexation of triprolidine hydrochloride (TRP) and β-cyclodextrin (β-CD) in deuterium oxide was investigated by 400 MHz 1^H NMR spectroscopy. The 800 MHz 2D ROESY data revealed that two 1 :1 and one 2 : 1 β-CD-TRP inclusion complexes were formed. Both aromatic moieties (p-tolyl and pyridyl ring) has entered into the β-CD cavity, confirming the existence of two different equilibria for 1 : 1 inclusion complexes in which p-tolyl ring of the guest is more tightly held by the host cavity. The ROE intermolecular interactions provided the plausible structures of these 1 : 1 and 2 : 1 stoichiometric inclusion complexes of β-CD-triprolidine hydrochloride in solu- tion. 相似文献