Aqueous chromatographic system for the quantification of propofol in biological fluids using a temperature-responsive polymer modified stationary phase

A new method for the quantitative analysis of monkey serum propofol, which is widely used as an anaesthetic agent, was developed by utilizing a temperature-responsive polymer of N-isopropylacrylamide (NIPAAm) and butyl methacrylate (BMA) as the stationary phase of HPLC–fluorescence detection. This poly(NIPAAm-co-BMA) copolymer undergoes a reversible phase transition from a hydrophilic to a hydrophobic microstructure when triggered by change in the temperature. Also this chromatographic system is possible to separate the analytes by using only water as a mobile phase. A pretreatment of the serum (80 μL) was only solid-phase extraction, and the recovery rate of propofol and internal standard was more than 77%, respectively. This method covered the calibration range from 0.5 μg/mL to 10 μg/mL and allowed a reproducible quantification of the serum propofol in administrated monkey serum. The intra- and inter-assay relative standard deviations were less than 14.1%. In addition, there was good relationship of the quantification values between the developed method and the widely used reversed-phase HPLC method. Our developed method has proven to be useful for a simple analysis of propofol in clinical practice, because the avoidance of complicated mobile phase preparation was possible, and only temperature changing could regulate the retention time of the analyte. In addition, by using water instead of fossil fuel, it is the ideal analytical method according to green chemistry.     

关注长江水质——“绿行之踪”社会实践

2018年和2019年小学期,厦门大学本科生"绿行之踪"社会实践队赴重庆、上海等长江流域主要城市进行社会实践活动,采集了当地的水样,测定了水样中的磷酸根含量和高锰酸盐指数,同时进行了水资源保护的宣传活动和网络问卷调查。     

Conceptual metaphors for isomorphism and homomorphism: Instructors’ descriptions for themselves and when teaching

Group isomorphism and homomorphism are topics central to abstract algebra, yet research on instructors’ views of these concepts is limited. Based on interviews from two instructors as well as classroom video from eight class periods, this paper examines the language used to discuss isomorphism and homomorphism. Language used by instructors in interviews and classroom settings are identified and classified into four main categories: formal definition, mapping, sameness, and combinations of sameness and mapping language. How the two instructors drew on language classified into those four categories in the interview and instruction settings are examined for isomorphism and homomorphism. Similarities and differences between the interview and instruction contexts reveal the wide variety of ways of understanding isomorphism and homomorphism as well as a research need to examine mathematicians’ content knowledge in more than one context.     

有机化学课程思政教学实践*

结合课程思政教学情况的现状,梳理了有机化学课程思政开展的过程实践,解释了有机化学课程思政教学目标的创设思路,列举了有机化学课程思政元素案例,阐述了有机化学课程思政教学的4个措施,并进行了有机化学课程思政教学效果的初步评价。     

大学物理实验教学改革

对比于国内现状．介绍了国外大学在大学物理实验教学中一些比较有意义的做法,指出学习借鉴的必要性。     

大学物理实验综合性项目设计与教学实践初探

本文介绍了在大学物理实验课程中引入综合性实验内容,从具体项目的确立,到教学的操作实施过程;从查阅文献制订实验方案、实施具体的实验步骤及撰写实验报告等各个方面,如何在各个教学环节中注重对学生科研设计能力的初步培养进行了阐述;并对实验的成绩评定方法做了一些有益的探讨．     

原子物理学课程的教学改革与实践

文章首先对原子物理学课程进行定位，指出原子物理学是普通物理的一部分，它属于近代物理，并概述了原子物理学课程的特点；文章接着对原子物理学课程的教学体系与教学内容的改革方面的一些重要问题分别进行了讨论；文章最后详述了原子物理学的教学改革与实践以及在教学中培养分析问题和解决问题的能力方面的尝试。     

Examining preservice teachers’ noticing of equity-based teaching practices to empower students engaging in productive struggle

Our study examined ways preservice teachers (PSTs) make connections between teaching practices and use of student resources that support productive struggle and promote equity. Our research questions are: (1) How do PSTs notice and describe the equity-based mathematics teaching practice of leveraging student resources to support student struggles? and (2) In what ways do PSTs make connections to and interpret the role student resources play in the resolution of students’ mathematical struggles? The qualitative study examined 39 PSTs in a mathematics content course for PSTs. Data come from a video analysis assignment where PSTs described their mathematical interpretations of the student struggle(s) and teacher’s use of student resources to support the struggle resolution. Findings show that PSTs noticed teacher moves that leveraged student’s mathematical thinking and linguistic funds of knowledge and based the productive level of the struggle on actions built upon peers, linguistic knowledge and prior mathematical knowledge.     

断陷盆地层滑带的发育特征及矿山开发条件下的再变形分析

层滑带在华北断陷盆地中具有普遍性,是影响地下矿山工程围岩稳定的重要因素之一。本文以鲁西矿区为例,阐述了断陷盆地层滑带的发育特征及其形成机制,进行了开挖、运营条件下层滑带再变形分析,并指出了层滑带发育区巷道设计及维护中应注意的某些问题。     

高分子材料与工程专业实践教学改革研究与探索

实践教学是培养大学生创新精神、创新能力和实践能力的最重要教学环节。本文阐述了高分子材料与工程专业实践教学的现状和存在的问题,总结了实验教学、生产实习、毕业设计这三大实践教学环节在人才培养过程中的重要作用。针对实践教学存在的问题和不足,我们着力构建新的培养模式和实践教学环境,增加研究性、探索性实践教学内容比例等,为培养具...