A novel condition for capillary electrophoretic analysis of reductively aminated saccharides without removal of excess reagents

We have identified novel CE conditions for the separation of 7‐amino‐4‐methylcoumarin‐labeled monosaccharides and oligosaccharides from glycoproteins. Using a neutrally coated capillary and alkaline borate buffer containing hydroxypropylcellulose and ACN, saccharide derivatives form anionic borate complexes, which move from the cathode to the anode in an electric field and are detected near the anodic end. Excess labeling reagents and other fluorescent products remain at the cathodic end. Fluorimetric detection using an LED as a light source enables determination of monosaccharide derivatives with good linearity between at least 0.4 and 400 μM, may correspond to 140 amol to 140 fmol. The lower LOD (S/N = 5) is only 80 nM in the sample solution (ca. 28 amol). The results were comparable to reported values using fluorometric detection LC. The method was also applied to the analysis of oligosaccharides that were enzymatically released from glycoproteins. Fine resolution enables profiling of glycans in glycoproteins. The applicability of the method was examined by applying it to other derivatives labeled with nonacidic tags such as ethyl p‐aminobenzoate‐ and 2‐aminoacridone‐labeled saccharides.     

Pairs of Semisimple Lie Algebras and their Maximal Reductive Subalgebras

Let \(\mathfrak g\) be a semisimple Lie algebra over a field \(\mathbb K\), \(\text{char}\left( \mathbb{K} \right)=0\), and \(\mathfrak g_1\) a subalgebra reductive in \(\mathfrak g\). Suppose that the restriction of the Killing form B of \(\mathfrak g\) to \(\mathfrak g_1 \times \mathfrak g_1\) is nondegenerate. Consider the following statements: ( 1) For any Cartan subalgebra \(\mathfrak h_1\) of \(\mathfrak g_1\) there is a unique Cartan subalgebra \(\mathfrak h\) of \(\mathfrak g\) containing \(\mathfrak h_1\); ( 2) \(\mathfrak g_1\) is self-normalizing in \(\mathfrak g\); ( 3) The B-orthogonal \(\mathfrak p\) of \(\mathfrak g_1\) in \(\mathfrak g\) is simple as a \(\mathfrak g_1\)-module for the adjoint representation. We give some answers to this natural question: For which pairs \((\mathfrak g,\mathfrak g_1)\) do ( 1), ( 2) or ( 3) hold? We also study how \(\mathfrak p\) in general decomposes as a \(\mathfrak g_1\)-module, and when \(\mathfrak g_1\) is a maximal subalgebra of \(\mathfrak g\). In particular suppose \((\mathfrak g,\sigma )\) is a pair with \(\mathfrak g\) as above and σ its automorphism of order m. Assume that \(\mathbb K\) contains a primitive m-th root of unity. Define \(\mathfrak g_1:=\mathfrak g^{\sigma}\), the fixed point algebra for σ. We prove the following generalization of a well known result for symmetric Lie algebras, i.e., for m=2: (a) \((\mathfrak g,\mathfrak g_1)\) satisfies ( 1); (b) For m prime, \((\mathfrak g,\mathfrak g_1)\) satisfies ( 2).     

Titanium (IV) as an essential promoter in the asymmetric addition of diethylzinc to aldehydes catalyzed by aminonaphthol and imine ligands based on 3-substituted binaphthol

By using indirect reductive amination and condensation, two types of aminonaphthol and imine ligands based on 3-substituted binaphthol have been synthesized, respectively. When their catalytic effectiveness was tested by the ethylation of aldehydes with diethylzinc, titanium tetraisopropoxide was found essential to get good results with ee up to 90%.     

Reductive immobilization and long-term remobilization of radioactive pertechnetate using bio-macromolecules stabilized zero valent iron nanoparticles

Carboxymethyl cellulose-and starch-stabilized nZVI nanoparticles were prepared and showed high efficiency for reductive immobilization of ⁹⁹TcO₄^- in simulated groundwater.     

Principe de densité pour les groupes rèuctifs

The main goal of this Letter is to give a new proof of a result conjectured by D. De George and N. Wallach and proved by P. Deborne and to extend it to the S-arithmetic setting. The proof is based on a density principle.     

Quantum integrable models of interacting bosons and classical r-matrices with spectral parameters

Using the technique of classical $r$-matrices with spectral parameters we construct a general form of quantum Lax operators of interacting boson systems corresponding to an arbitrary simple (or reductive) Lie algebra. We prove quantum integrability of these models in the physically important case of $\mathfrak{g}=gl\left(n\right)$ and “diagonal” in the root basis classical $r$-matrices. We consider in detail two classes of non-skew-symmetric classical $r$-matrices with spectral parameters and obtain the corresponding quantum Lax operators and quantum integrable many-boson hamiltonians that generalize Bose–Hubbard dimer hamiltonians.     

Generation of quaternary centers by reductive cross-coupling: shifting of regioselectivity in a subset of allylic alcohol-based coupling reactions

Regioselective titanium alkoxide-mediated reductive cross-coupling reactions of allylic alcohols with vinylsilanes and imines have previously been demonstrated to proceed with allylic transposition by formal metallo-[3,3]-rearrangement [thought to proceed by a sequence of: (1) directed carbometalation, and (2) syn-elimination]. While many examples have been described that support this reaction path, a collection of substrates have recently been identified that react by way of an alternative pathway, delivering a concise convergent route to coupled products bearing a quaternary center.     

Towards schizozygine: synthesis of 15α-hydroxystrempeliopine

15α-Hydroxystrempeliopine (6), a model hexacyclic base for our planned total synthesis of schizozygine (2), has been synthesized using a Zn-mediated reductive rearrangement of indolenine 14 as the key step. The structure and relative stereochemistry of 6 were assigned by a combination of COSY, NOESY, HSQC and HMBC correlations.     

纳米结构锌及锌氧化物薄膜对甲基橙的降解作用研

采用磁控溅射方法制备了纳米金属锌薄膜,结合后续的空气退火处理制备了纳米锌氧化物薄膜. 金属锌薄膜对甲基橙的还原降解以及锌氧化物薄膜对甲基橙的光催化降解过程都可以用一级反应动力学方程来描述. 甲基橙溶液在金属锌膜的还原降解下具有最快的褪色速率,但矿化不完全：在紫外光波段出现的额外吸收峰表明生成了芳香族中间产物. 完全氧化的氧化锌薄膜对甲基橙的光催化降解速率仅为金属锌膜还原降解速率的1/4左右,没有出现芳香族中间产物. 另外实验发现部分氧化的锌氧化物薄膜对甲基橙的光催化降解速率明显高于完全氧化的氧化锌薄膜,光催化活性的提高可能由于部分氧化薄膜中同时存在的金属锌及氧化锌相之间的协同效应.     

Reductivity of the Lie Algebra of a Bilinear Form

Let f: V × V → F be a totally arbitrary bilinear form defined on a finite dimensional vector space V over a field F, and let L(f) be the subalgebra of 𝔤𝔩(V) of all skew-adjoint endomorphisms relative to f. Provided F is algebraically closed of characteristic not 2, we determine all f, up to equivalence, such that L(f) is reductive. As a consequence, we find, over an arbitrary field, necessary and sufficient conditions for L(f) to be simple, semisimple or isomorphic to 𝔰𝔩(n) for some n.