Separation of neutral and basic enantiomers by cyclodextrin electrokinetic chromatography using anionic cyclodextrin derivatives as chiral pseudo-stationary phases

Separations of neutral and basic racemates were performed using five different anionic cyclodextrin (CD) derivatives as chiral selectors, viz. carboxymethylated β-CD, β-CD phosphate sodium salt, sulfobutyl ether β-CD sodium salt, carboxymethylated γ-CD, and γ-CD phosphate sodium salt. For the separation of neutral racemates, an untreated fused silica capillary was employed and various neutral racemates were successfully separated. Since the pH of the buffer affected the electroosmotic flow (EOF), the resolution was improved by changing the buffer pH. A polyacrylamide coated capillary was employed for the separation of basic racemates to suppress EOF and to prevent adsorption of cationic analyte on the capillary surface. By choosing an appropriate type and concentration of anionic CD, about 40 basic racemates were successfully separated. Some rough binding constants of basic analytes with an anionic β-CD were measured to discuss the optimum concentration of the CD. The migration direction was dependent on the binding constants and the concentration of the CD. The analyte strongly bound to the anionic CD migrated towards the anode but the weakly bound one moved towards the cathode. Anionic γ-CDs were also very useful for the separation of basic enantiomers. Five neutral CDs were employed as chiral selectors to compare selectivity between charged and neutral CDs, and eleven racemates could only be resolved using anionic CDs. The separation of some basic racemates in human plasma was also described. The direct injection of plasma samples was possible for some enantiomers that did not interact strongly with plasma proteins.     

Reactivity and electronic property of decaphenylmetallocenes of Mo and W atoms

The perphenylmetallocene complexes (η⁵-C₅Ph₅)₂W (1), [(η⁵-C₅Ph₅)₂W]⁺I₃⁻ (1⁺I₃), (η⁵-C₅Ph₅)₂Mo (2) and [(η⁵-C₅Ph₅)₂Mo]⁺I₃⁻ (2⁺I₃) have been prepared. Hydrogenation of 1 in THF produces (η⁵-C₅Ph₅)₂WH₂ (4), while (η⁵-C₅Ph₅)₂WHCl (3) is afforded in 1,2-dichloroethane solvent. Carbonylation of 1 produces (η⁵-C₅Ph₅)₂W(CO) (5). Treatment of 1 with the strong acid CF₃SO₃H leads to the dicationic species [(η⁵-C₅Ph₅)₂W]⁺²[CF₃SO₃]⁻₂ (1⁺²Tf₂) after crystallization. The structures of 2⁺I₃ and 1⁺²Tf₂ have been determined by an X-ray diffraction study. The magnetic susceptibility study indicates a ³E_2g ground-state for 1 and 2, and a ⁴A_2g ground-state for 1⁺ and 2⁺.     

若干中性配体对Mo—Fe—S簇合物自兜的影响

通过电子吸收光谱的变化研究了一些含N和含P中性配体对MoS_4~(2-)-nFeCl_2-DMF体系形成立方烷型Mo-Fe-S簇合物的可能影响。     

Spectroelectrochemical Investigation on Neutral Red

Neutral Red can be used as an indicator, a stain reagent or a mediator compound in the studies of biological redox systems. No reports dealing with the electrode process of Neutral Red, especially, about its kinetics have been published. In this paper we report the determinations of formal reduction potentials, the number of electrons transferred, diffusion coefficient as well as the rate constant of heterogeneous electron transfer     

Exponential stability of nonlinear impulsive neutral integro-differential equations

In this paper, a nonlinear impulsive neutral integro-differential equation with time-varying delays is considered. By establishing a singular impulsive delay integro-differential inequality and transforming the n$n$-dimensional impulsive neutral integro-differential equation to a 2n$2n$-dimensional singular impulsive delay integro-differential equation, some sufficient conditions ensuring the global exponential stability in PC¹$P{C}^1$ of the zero solution of an impulsive neutral integro-differential equation are obtained. The results extend and improve the earlier publications. An example is also discussed to illustrate the efficiency of the obtained results.     

一类中立型脉冲时滞生物模型的正周期解(英文)

运用严格集压缩映射不动点定理,讨论得到了一类中立型脉冲时滞生物模型正周期解存在的充分条件.我们去掉了文[6,7,12-14]周期解存在的一些条件,推广了对应的结果.     

NONLINEAR STABILITY OF NATURAL RUNGE-KUTTA METHODS FOR NEUTRAL DELAY DIFFERENTIAL EQUATIONS

This paper first presents the stability analysis of theoretical solutions for a class of nonlinear neutral delay-differential equations (NDDEs). Then the numerical analogous results, of the natural Runge-Kutta (NRK) methods for the same class of nonlinear NDDEs, are given. In particular, it is shown that the (k, l)-algebraic stability of a RK method for ODEs implies the generalized asymptotic stability and the global stability of the induced NRK method.     

On a Delay Reaction-Diffusion Difference Equation of Neutral Type

In this paper, we first consider a delay difference equation of neutral type of the form: Δ(y _n + py _n−k + q _n y _n−l = 0 for n∈ℤ⁺(0) (1*) and give a different condition from that of Yu and Wang (Funkcial Ekvac, 1994, 37(2): 241–248) to guarantee that every non-oscillatory solution of (1*) with p = 1 tends to zero as n→∞. Moreover, we consider a delay reaction-diffusion difference equation of neutral type of the form: Δ₁(u _n,m + pu _n−k,m ) + q _n,m u _n−l,m = a ²Δ² ₂ u _{n +1, m−1} for (n,m) ∈ℤ⁺ (0) ×Ω, (2*) study various cases of p in the neutral term and obtain that if p≥−1 then every non-oscillatory solution of (2*) tends uniformly in m∈Ω to zero as n→∞; if p = −1 then every solution of (2*) oscillates and if p < −1 then every non-oscillatory solution of (2*) goes uniformly in m∈Ω to infinity or minus infinity as n→∞ under some hypotheses. Received July 14, 1999, Revised August 10, 2000, Accepted September 30, 2000     

中立型微分方程零解的稳定性与全局Hopf分支

本文用Ｒｏｕｃｈｅ定理建立起关于一般的超越函数的零点分布定理，以此定理为基础，结合应用吴建宏等用等变拓扑度理论建立起的一般泛函微分方程的Ｈｏｐｆ分支定理，研究了描述无损传输网络线路的中立型微分方程的零解的稳定性和全局Ｈｏｐｆ分支．     

中立型时滞微分方程的渐近稳定性

考虑具有正负系数的中立型时滞微分方程ｄｄ狋［狓（狋）－犘（狋）狓（狋－τ）］＋犙（狋）狓（狋－δ）－犚（狋）狓（狋－σ）＝０，　狋≥狋０， 其中Ｐ（ｔ）∈Ｃ（［ｔ０，∞），Ｒ），Ｑ（ｔ），Ｒ（ｔ）∈Ｃ（［ｔ０，∞），Ｒ＋ ），τ，δ，σ∈（０，∞）．获得了该方程零解 一致稳定及渐近稳定的充分条件，它推广并改进了现有文献中的结论．