Meiran Zhang  Wei Zheng  Yan Liu  Ping Huang  Zhongliang Gong  Jiaojiao Wei  Yu Gao  Shanyong Zhou  Xingjun Li  Xueyuan Chen 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2019,131(28):9656-9660

Lanthanide (Ln³⁺)‐doped luminescent nanoparticles (NPs) with emission in the second near‐infrared (NIR‐II) biological window have shown great promise but their applications are currently limited by the low absorption efficiency of Ln³⁺ owing to the parity‐forbidden 4f→4f electronic transition. Herein, we developed a strategy for the controlled synthesis of a new class of NIR‐II luminescent nanoprobes based on Ce³⁺/Er³⁺ and Ce³⁺/Nd³⁺ co‐doped CaS NPs, which can be effectively excited by using a low‐cost blue light‐emitting diode chip. Through sensitization by the allowed 4f→5d transition of Ce³⁺, intense NIR‐II luminescence from Er³⁺ and Nd³⁺ with quantum yields of 9.3 % and 7.7 % was achieved, respectively. By coating them with a layer of amphiphilic phospholipids, these NPs exhibit excellent stability in water and can be exploited as sensitive NIR‐II luminescent nanoprobes for the accurate detection of an important disease biomarker, xanthine, with a detection limit of 32.0 nm .  相似文献