全文获取类型
收费全文 | 5165篇 |
免费 | 232篇 |
国内免费 | 249篇 |
专业分类
化学 | 1363篇 |
晶体学 | 2篇 |
力学 | 223篇 |
综合类 | 55篇 |
数学 | 2914篇 |
物理学 | 1089篇 |
出版年
2024年 | 13篇 |
2023年 | 72篇 |
2022年 | 123篇 |
2021年 | 133篇 |
2020年 | 94篇 |
2019年 | 118篇 |
2018年 | 94篇 |
2017年 | 177篇 |
2016年 | 194篇 |
2015年 | 124篇 |
2014年 | 322篇 |
2013年 | 440篇 |
2012年 | 254篇 |
2011年 | 316篇 |
2010年 | 278篇 |
2009年 | 350篇 |
2008年 | 307篇 |
2007年 | 342篇 |
2006年 | 275篇 |
2005年 | 199篇 |
2004年 | 184篇 |
2003年 | 142篇 |
2002年 | 116篇 |
2001年 | 101篇 |
2000年 | 93篇 |
1999年 | 107篇 |
1998年 | 106篇 |
1997年 | 78篇 |
1996年 | 70篇 |
1995年 | 51篇 |
1994年 | 56篇 |
1993年 | 33篇 |
1992年 | 42篇 |
1991年 | 35篇 |
1990年 | 20篇 |
1989年 | 21篇 |
1988年 | 20篇 |
1987年 | 12篇 |
1986年 | 14篇 |
1985年 | 22篇 |
1984年 | 25篇 |
1983年 | 9篇 |
1982年 | 5篇 |
1981年 | 10篇 |
1980年 | 12篇 |
1979年 | 10篇 |
1978年 | 7篇 |
1977年 | 9篇 |
1976年 | 4篇 |
1973年 | 3篇 |
排序方式: 共有5646条查询结果,搜索用时 15 毫秒
91.
I.I. Baskin S. Lozano M. Durot G. Marcou D. Horvath 《SAR and QSAR in environmental research》2020,31(8):597-613
ABSTRACT Here we report a new predictive model for autoignition temperature (AIT), an important physical parameter widely used to assess potential safety hazards of combustible materials. Available structure-AIT data extracted from different sources were critically analysed. Support vector regression (SVR) models on different data subsets were built in order to identify a reliable compound set on which a realistic model could be built. This led to a selection of the dataset containing 875 compounds annotated with AIT values. The thereupon-based SVR model performs reasonably well in cross-validation with the determination coefficient r 2 = 0.77 and mean absolute error MAE = 37.8°C. External validation on 20 industrial compounds missing in the training set confirmed its good predictive power (MAE = 28.7°C). 相似文献
92.
New mixed-ligand copper(I) complexes, [Cu(Phca2en)(PPh3)X], [Phca2en = N,N′-bis(β-phenylci-nnamaldehyde)-1,2-diiminoethane and X=Cl (1), Br (2), I (3), NCS (4), N3 (5)] have been synthesized and characterized by various techniques. 1H and 13C-NMR and IR spectral data of these copper(I) complexes are compared with the free ligand to elucidate some structural features. The structures of [Cu(Phca2en)(PPh3)Br] (2) and [Cu(Phca2en)(PPh3)I] (3) have been determined from single-crystal data showing that the coordination geometry around copper atom is a distorted tetrahedron. Furthermore, these Cu(I) complexes exhibit supramolecular motifs of the type multiple phenyl embraces resulting from attractive interactions between phenyl rings of PPh3 moieties. The presence of the C–H…Cu weak intramolecular hydrogen bonds, due to the trapping of C–H bonds in the vicinity of the metal atoms, is also reported. 相似文献
93.
We have evaluated the potential of near-infrared spectroscopy (NIRS) as a technique for rapid analysis of lactate in whole blood. To test the NIRS technique, a comparison was made with a standard clinical method using whole blood samples taken from five exercising human subjects at three different stage of exercise. To expand lactate concentration within the physiological range, standard additions method was used to generate 45 unique data points. Spectra were collected over the 2050-2400 nm spectral range with a 1 mm optical path length quartz cell. Reference lactate concentrations in the samples were determined by enzymatic measurements. Estimates and calibration of the lactate concentration with NIRS was made using partial least squares (PLS) regression analysis and leave-N-out cross validation on second derivative spectra. Separate calibrations were determined from each of the subject samples and cumulative PRESS was used to determine the number of PLS factors in the final model. The results from the PLS model presented are generated from the five individual calibration coefficient vectors and provided a correlation coefficient of 0.978 and a standard error of cross validation of 0.65 mmol l−1 between the enzymatic assay and the NIRS technique. To study the parameters that impact the spectra baseline and the correlation between the calculated model and the data, referenced measurements of lactate against baseline spectrum were made for each individual. A correlation coefficient of 0.992 and a standard error of cross validation of 0.21 mmol l−1 were found. The results suggest that NIRS may provide a valuable tool to assess physiological status for both research and clinical needs. 相似文献
94.
Antonio Fernández-Ramos Benjamin A. Ellingson Rubén Meana-Pañeda Jorge M. C. Marques Donald G. Truhlar 《Theoretical chemistry accounts》2007,118(4):813-826
This article shows how to evaluate rotational symmetry numbers for different molecular configurations and how to apply them
to transition state theory. In general, the symmetry number is given by the ratio of the reactant and transition state rotational
symmetry numbers. However, special care is advised in the evaluation of symmetry numbers in the following situations: (i)
if the reaction is symmetric, (ii) if reactants and/or transition states are chiral, (iii) if the reaction has multiple conformers
for reactants and/or transition states and, (iv) if there is an internal rotation of part of the molecular system. All these
four situations are treated systematically and analyzed in detail in the present article. We also include a large number of
examples to clarify some complicated situations, and in the last section we discuss an example involving an achiral diasteroisomer. 相似文献
95.
96.
I. Kanakis C. Stavropoulou F. N. Lamari Y. Heliopoulos H. Iordanidou H. Piperidou D. Monos N. K. Karamanos 《Chromatographia》2003,58(7-8):513-516
Summary Multiple sclerosis (MS) is an autoimmune disease characterized by the production of specific types of immunoglobulins into the central nervous system. These immunoglobulins appear as oligoclonal bands (OCBs) in agarose isoelectric focusing (IEF) of cerebrospinal fluid (CSF). Among the cases with clinically definite MS, up to 95% have oligoclonal IgG bands in their CSF. In this report, we describe a micellar electrokinetic capillary chromatography (MEKC) method for the separation of CSF and serum proteins. MEKC was performed using 25 mM borate buffer, pH 10, containing 25 mM SDS at 20 kV and normal polarity. High values of repeatability in migration times and of reproducibility in peak areas were obtained (R.S.D. values were less than 2%). Calibration graphs were linear up to 2000 mg L–1. LOQ was 6.5 mg L–1 and LOD determined as a signal to noise ration of 3:1 was 4.5 mg L–1. Analysis of CSF and serum samples from patients with clinical definite MS and healthy individuals demonstrated the presence of two peaks migrating as -globulins in the CSF samples of patients. These peaks were absent from controls and the serum of the same patients. Correlation of the data obtained from IEF and MEKC analysis for 25 patients showed that the diagnostic sensitivity and specificity of MEKC were ca 89% and 92% respectively. The obtained results indicate that this MEKC method may be helpful for the diagnosis of multiple sclerosis. Capillary electrophoresis compared to flat bed IEF provides reproducible results, requires shorter analysis time, and allows direct quantitative determination.Presented at: International Symposium on Separation and Characterization of Natural and Synthetic Macromolecules, Amsterdam, TheNetherlands, February 5–7, 2003 相似文献
97.
98.
Summary INDO molecular orbital calculations are reported for 35 selected angiotensin-converting enzyme inhibitors. QSARs are developed between pI50 data and molecular electronic indices. The QSARs obtained reflect the importance of both charge-charge interactions between inhibitor and receptor and of specific interactions between groups on the inhibitor with points around the molecule which are postulated to correspond to binding sites at the receptor. 相似文献
99.
100.
Arrhenius parameters values, in non-isothermal kinetic vaporisation processes for a series of compounds with related structures,
have been calculated. This was made using a method of calculation that allows to find the most probable vaporisation mechanisms.
According to this method DTG curves were compared with some theoretical ones reported in literature, whose shape results to
be only a function of the mechanisms. In this way the choice of the mathematical functions which can be inserted in the kinetic
equations, was influenced by the shape of the DTG plots and other thermal analysis signals thus allowing to choose the most
probable mechanisms.
The kinetic parameters derived from these mechanisms were compared, using statistical analysis, with those obtained from another
method of calculation based on ‘a priori’ vaporisation mechanism chosen for the investigated liquid–gas transition.
The standard deviations of the slope and of the intercept, together with the standard deviation and the square correlation
coefficient (r
2) of the linear regression equations related to the mechanisms of the two methods were calculated. Student t-test, Fisher F-test, confidence intervals (c.i.) and residuals valueswere also given.
Statistical analysis shows that the mechanisms obtained with the former method (diffusive and geometrical models) and the
related Arrhenius parameters result to be more significant (in terms of probability) than the corresponding quantities of
the latter for which a first-order model was chosen.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献