钯催化氟磺酸酚酯Suzuki反应合成三联苯类化合物

发展了一个高效、简便合成三联苯类化合物的方法。以氯化钯为催化剂,碳酸钾与三乙胺为碱,无需加入任何配体,在乙醇水溶液中催化氟磺酸联苯酚酯与芳基硼酸的Suzuki反应,可高效合成含有多种官能团的三联苯类化合物。该方法操作简便,无需氮气保护;且芳基硼酸自偶联副产物少,有利于产品的分离。为三联苯类化合物的合成提供了一条简便而高效的途径。     

Synthesis of phthalides via Pd/CNTs-catalyzed reaction of terminal alkynes and o-iodobenzoic acid under copper- and ligand-free conditions

A phosphine- and copper-free protocol for the synthesis of phthalides via Pd/CNTs-catalyzed tandem coupling-cyclization process has been developed. The palladium immobilized on CNTs showed high catalytic activity, and the reactions with a variety of terminal alkynes and o-iodobenoic acid proceeded smoothly to give phthalides in moderate to good yields catalyzed by 0.1% mmol Pd/CNTs.     

Ligand-Free Metal Clusters

Recent advances in the synthesis and spectroscopic characterization of ligand-free metal clusters immobilized in cryogenic rare gas matrices have contributed greatly to the understanding of electronic, geometric, dynamic, and chemical bonding properties of a wide range of uni- and bimetallic clusters as a function of nuclearity and metal type. The knowledge accumulated on molecular metal aggregates devoid of ligands and isolated on various supports will form an important data base for gauging the reliability of quantum chemical calculations on metal clusters, as well as for comprehending certain aspects of chemisorption on, and catalysis by, supported metal clusters. It can be envisaged that information on ligand-free metal clusters entrapped in a wide range of matrix environments in conjunction with the data for these same metal clusters in the gas phase and in molecular beams will probably contribute towards understanding metal-support interactions and to the designed synthesis of a new breed of high-technology heterogeneous catalysts in the not too distant future.