基于桥域理论的Cu单晶纳米切削跨尺度仿真研究

桥域方法是一种典型的跨尺度仿真研究方法.基于桥域理论,本文分析了原子和连续介质耦合区域的处理问题,即在耦合区采用不同的权重计算系统的能量,通过Lagrange乘子法对原子和连续介质位移进行约束.采用桥域方法,建立了单晶Cu米纳切削的跨尺度仿真模型,获得了单晶Cu纳米切削的材料变形机理.同时,研究了不同切削速度对纳米切削过程和原子受力分布的影响,仿真结果表明:随着切削速度的提高,切削区原子所受的力值增大,切屑变形系数减小,已加工表面变质层厚度增加.本文基于桥域理论,实现了Cu单晶纳米切削跨尺度的建模和仿真, 关键词： 桥域法 纳米切削 单晶Cu 切削速度     

Wireless retrospective gating: Application to cine cardiac imaging

A new “wireless” method of cardiac imaging is introduced, which, unlike ECG triggering, allows imaging the heart at end-diastole, and greatly reduces smearing artifacts in the phase-encoding direction. It is an improvement over ECG-driven retrospective gating, in that patients with poor ECGs can be imaged. This method extends the applicability of cardiac imaging, and since it requires no physiological monitoring hardware, can be implemented easily on any MR imager. The images produced by this method are superior to those from ECG triggering, especially when viewed in a “cine” loop. The technique described herein is, furthermore, extendable to any area where periodic or quasi-periodic motion is a problem.     

Alternative configurations for cutting machines in a tube cutting mill

In a steel tube mill where an endless stream of steel tube is supplied from a manufacturing facility, trim waste is never made regardless of cutting patterns used and the standard cutting stock problem seems meaningless. Therefore, the continuous stock cutting problem with setup is introduced to minimize the sum of cutting time and pattern changing time to meet the given demand. We propose a new configuration of cutting machines to achieve higher production efficiency, namely the open-ended configuration as opposed to the traditional closed-ended configuration, thereby two variants of the problem are defined. We propose linear formulations for both problems using binary expansion of the number of pieces of different types in a pattern. Furthermore, we define the time for pattern change as a linear function of the number of knives used in the pattern to be more realistic. Computational studies suggest that the open-ended cutting machine may improve the production time by up to 44% and that our linear formulations are more efficient than the existing ones.     

On Global Optimality Conditions and Cutting Plane Algorithms

We discuss global optimality conditions and cutting plane algorithms for DC optimization. The discussion is motivated by certain incorrect results that have appeared recently in the literature on these topics. Incidentally, we investigate the relation of the Tikhonov reciprocity theorem to the optimality conditions for general nonconvex global optimization problems and show how the outer-approximation scheme developed earlier for DC programming can be used to solve a wider class of problems.     

受模糊干扰的再生型颤振的模糊稳定性分析

首次在机床切削颤振分析中考虑了模糊不确定性因素的影响，利用模糊数学分析方法详细论述了受模糊干扰的再生型颤振的模糊稳定性分析问题，给出了模糊稳定性极限切削宽度集合的可能性分布及其置信区间表达式，最后依据所提出的理论分析方法，经计算编程绘制了模糊稳定性图。     

The use of online heart‐cutting high‐performance liquid chromatography coupled with linear ion trap mass spectrometry in the identification of impurities in vidarabine monophosphate

It is difficult to identify unknown impurities in nucleotide analogues by mass spectrometry because mass‐spectrometry‐incompatible mobile phases need to be used to separate the major ingredient from impurities. In this study, vidarabine monophosphate was selected, and unknown impurities were identified by online heart‐cutting two‐dimensional high‐performance liquid chromatography and linear ion trap mass spectrometry. The one‐dimensional reversed‐phase column was filled with a mobile phase containing nonvolatile salt. In two‐dimensional high‐performance liquid chromatography, we used an Acclaim Q1 column with volatile salt, and the detection wavelength was 260 nm. The mass spectrum was scanned in positive‐ and negative‐ion mode. The online heart‐cutting and online demineralization technique ensured that the mobile phase was compatible with mass spectrometry; seven impurities were identified by MS² and MS³ fragments. The mass fragmentation patterns of these impurities were investigated. The two isomers were semiprepared and complemented by nuclear magnetic resonance. The results were further compared with those of normal‐phase high‐performance liquid chromatography with mass spectrometry. The online heart‐cutting two‐dimensional high‐performance liquid chromatography with mass spectrometry was superior in identifying more impurities. The method solves the problem of incompatibility between the mobile phase and mass spectrometry, so it is suitable for identifying unknown impurities. This method may also be used for investigating impurities in other nucleotide analogues.     

Analysis of volatiles associated with industrial scale processing of expanded polystyrene Part II: Identification and quantitation

Expanded polystyrene was pyrolyzed on a laboratory scale hot wire cutter. The resulting volatiles were characterized using GC/MS as the primary analytical tool. Use was also made of retention data from a complex petrochemical standard. In situ bromination of the pyrolysate further helped in structure elucidation. Air samples were collected in the field and compared to the model experiments from a laboratory scale hot wire cutter. The results indicate that alkylbenzene type compounds were the primary compounds in this environment. A few oxygenated substances were also formed. Traces of brominated compounds were detected in the model experiments but not in the samples collected in the field, with one exception. Quantitative data are presented from a typical industrial operation.     

Superparamagnetic iron oxide particles and positive enhancement for myocardial perfusion studies assessed by subsecond T1-weighted MRI

Superparamagnetic iron oxide particles (SPIOs) are usually referred to as T₂ MR contrast agents, reducing signal intensity (SI) on T₂-weighted MR images (negative enhancement). This study reports the original use of SPIOs as T₁-enhancing contrast agents, primarily assessed in vitro, and then applied to an in vivo investigation of a myocardial perfusion defect. Using a strongly T₁-weighted subsecond MR sequence with SPIOs intravenous (IV) bolus injection, MR imaging of myocardial vascularization after reperfusion was performed, on a dog model of coronary occlusion followed by reperfusion. Immediately after the intravenous bolus injection of 20 μmol/kg of SPIOs, a positive signal intensity enhancement was observed respectively, in the right and left ventricular cavity and in the nonischemic left myocardium. Moreover, compared to normal myocardium, the remaining ischemic myocardial region (anterior wall of the left ventricle) appeared as a lower and delayed SI enhancing area (cold spot). Mean peak SIE in the nonischemic myocardium (posterior wall) was significantly higher than in the ischemic myocardium (anterior wall) (110 ± 23% vs. 74 ± 22%, Mann-Whitney test < 1%, n₁ = 6, n₂ − n₁ = 0, U > 2). In conclusion, the T₁ effect of SPIOs at low dose, during their first intravascular distribution, suggests their potential use as positive markers to investigate the regional myocardial blood flow and some perfusion defects such as the “no-reflow phenomenon”.     

桉树扦插育苗正交试验设计分析

根据扦插育苗试验表明，影响泰国赤桉苗高、根长及发根数的主要因素各不相同。综合分析表明：其主要因素是ＢＡ浓度，插条浸泡药液的时间和蔗糖浓度，其较优的插条处理方法是将插条在０．６％蔗糖＋３００ＰＰｍＩＢＡ溶液中浸泡２小时     

An interactive method for multiple-objective mathematical programming problems

An interactive method is developed for solving the general nonlinear multiple objective mathematical programming problems. The method asks the decision maker to provide partial information (local tradeoff ratios) about his utility (preference) function at each iteration. Using the information, the method generates an efficient solution and presents it to the decision maker. In so doing, the best compromise solution is sought in a finite number of iterations. This method differs from the existing feasible direction methods in that (i) it allows the decision maker to consider only efficient solutions throughout, (ii) the requirement of line search is optional, and (iii) it solves the problems with linear objective functions and linear utility function in one iteration. Using various problems selected from the literature, five line search variations of the method are tested and compared to one another. The nonexisting decision maker is simulated using three different recognition levels, and their impact on the method is also investigated.