New nanomolar negative modulators of AMPA receptors

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新型希夫碱型钳形人工受体的微波合成及其对中性分子的识别性能

以对苯二甲酸为起始原料,设计并合成了8个新型的芳环钳形人工受体(3a～3h),其结构经1H NMR,IR,ESI-MS和元素分析表征。利用UV-Vis滴定法初步考察了3a～3h对中性分子(邻苯二胺,间苯二胺,对苯二胺和二苯甲酮)的识别性能,结果表明3a～3h对其具有良好的识别性能。     

On Shellsort and the frobenius problem

A boundO(N ^1+1/k ) for the running time of Shellsort, withO(logN) passes, is proved very simply by application of a Frobenius basis withk elements.     

On the Gerber-Shiu function and change of measure

We consider several models for the surplus of an insurance company mainly under some light-tail assumptions. We are interested in the expected discounted penalty at ruin. By a change of measure we remove the discounting, which simplifies the expression. This leads to (defective) renewal equations as they had been found by different methods in the literature. If we use the change of measure such that ruin becomes certain, the renewal equations simplify to ordinary renewal equations. This helps to discuss the asymptotics as the initial capital goes to infinity. For phase-type claim sizes, explicit formulae can be derived.     

Towards an ‘average’ version of the Birch and Swinnerton-Dyer conjecture

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The Birch and Swinnerton-Dyer conjecture states that the rank of the Mordell-Weil group of an elliptic curve E equals the order of vanishing at the central point of the associated L-function L(s,E). Previous investigations have focused on bounding how far we must go above the central point to be assured of finding a zero, bounding the rank of a fixed curve or on bounding the average rank in a family. Mestre (1986) [Mes] showed the first zero occurs by , where NE is the conductor of E, though we expect the correct scale to study the zeros near the central point is the significantly smaller . We significantly improve on Mestre's result by averaging over a one-parameter family of elliptic curves E over Q(T). We assume GRH, Tate's conjecture if E is not a rational surface, and either the ABC or the Square-Free Sieve Conjecture if the discriminant has an irreducible polynomial factor of degree at least 4. We find non-trivial upper and lower bounds for the average number of normalized zeros in intervals on the order of (which is the expected scale). Our results may be interpreted as providing further evidence in support of the Birch and Swinnerton-Dyer conjecture, as well as the Katz-Sarnak density conjecture from random matrix theory (as the number of zeros predicted by random matrix theory lies between our upper and lower bounds). These methods may be applied to additional families of L-functions.

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For a video summary of this paper, please click here or visit http://www.youtube.com/watch?v=3EVYPNi_LG0.     

Sample path Large Deviations and optimal importance sampling for stochastic volatility models

Sample path Large Deviation Principles (LDP) of the Freidlin–Wentzell type are derived for a class of diffusions, which govern the price dynamics in common stochastic volatility models from Mathematical Finance. LDP are obtained by relaxing the non-degeneracy requirement on the diffusion matrix in the standard theory of Freidlin and Wentzell. As an application, a sample path LDP is proved for the price process in the Heston stochastic volatility model.     

The Decay of Massive Scalar Field in Non-Static Gödel Type Universe with Viscous Fluid and Heat Flow

In this study, we have investigated the dynamics of non-static Gödel type rotating universe with massive scalar field, viscous fluid and heat flow in the presence of cosmological constant. For various cosmic matter forms, the behavior of the cosmological constant (Λ), shear (η) and bulk (ξ) viscosity coefficients and other kinematic quantities have studied in the early universe. We have showed the decay of massive scalar field in the non-static rotating Gödel type universe and we have obtained constant scalar field with and without source density. Also, we have investigated the effects of massive scalar field on the matter density and pressure. From solutions of the field equations, we have a cosmological model with non-zero expansion, shear, heat flux and rotation. Also some physical and geometrical aspects of the model discussed.     

Explicit Mumford isomorphism for hyperelliptic curves

Using an explicit version of the Mumford isomorphism on the moduli space of hyperelliptic curves we derive a closed formula for the Arakelov-Green function of a hyperelliptic Riemann surface evaluated at its Weierstrass points.     

Inclusion isotonicity of circular complex centered forms

This paper presents a proof for the fact that the circular complex centered form is inclusion isotone for arbitrary analytic functions.