混合制冷剂循环(MRC)液化天然气流程的设备模拟

混合制冷剂液化天然气流程中 ,涉及到很多设备。文中介绍了压缩机、膨胀机和节流阀、分离器、混合器、多股流换热器这五类设备的热力学状态的计算方法 ,并与国外流程计算中的相应模块计算结果相比较 ,模拟结果十分接近 ,从而表明所进行的设备热力学状态模拟是正确的     

约束优化问题的一类光滑罚算法的全局收敛特性

对约束优化问题给出了一类光滑罚算法.它是基于一类光滑逼近精确罚函数 l_p(p\in(0,1]) 的光滑函数 L_p 而提出的.在非常弱的条件下, 建立了算法的一个摄动定理, 导出了算法的全局收敛性.特别地, 在广义Mangasarian-Fromovitz约束规范假设下, 证明了当 p=1 时, 算法经过有限步迭代后, 所有迭代点都是原问题的可行解; p\in(0,1) 时,算法经过有限迭代后, 所有迭代点都是原问题可行解集的内点.     

On the Classical Necessary Second-Order Optimality Conditions

In this paper, the property of a necessary second-order optimality condition to hold with the same Lagrange multiplier for all critical vectors is investigated. It is limited to nonconvex optimization Problems in ⁿ with equality and inequality constraints; the Mangasarian-Fromovitz constraint qualification is assumed to be hold. A counterexample was given recently by Anitescu. We give some sufficient conditions and we prove that this property holds if n 2 or if the number of active inequality constraints is at most two. For three active inequality constraints and n =3, a counterexample is given.     

Second-order and related extremality conditions in nonlinear programming

This paper is concerned with the problem of characterizing a local minimum of a mathematical programming problem with equality and inequality constraints. The main object is to derive second-order conditions, involving the Hessians of the functions, or related results where some other curvature information is used. The necessary conditions are of the Fritz John type and do not require a constraint qualification. Both the necessary conditions and the sufficient conditions are given in equivalent pairs of primal and dual formulations.This research was partly supported by Project No. NR-947-021, ONR Contract No. N00014-75-0569, with the Center for Cybernetic Studies, and by the National Science Foundation, Grant No. NSF-ENG-76-10260.     

An extension lemma and homogeneous programming

An extension lemma, which is equivalent to the generalized Gordan's theorem of the alternative, due to Fan, Glicksberg, and Hoffman, is applied to present a duality theory for a general class of homogeneous programs, with and without a constraint qualification of Slater type. In addition, an existence theorem for optimal solutions of homogeneous programs is given.The author thanks an anonymous referee for valuable suggestions about an earlier draft of this paper.     

Sandwich theorem for quasiconvex functions and its applications

In convex programming, sandwich theorem is very important because it is equivalent to Fenchel duality theorem. In this paper, we investigate a sandwich theorem for quasiconvex functions. Also, we consider some applications for quasiconvex programming.     

A high-resolution capillary isoelectric focusing method for the determination of therapeutic recombinant monoclonal antibody

Capillary isoelectric focusing (CIEF) is a common choice for separation and analysis of the charge variants and impurities of therapeutic proteins. In this study, we developed a sensitive CIEF analysis method for determining the charge heterogeneity of therapeutic monoclonal antibody (mAb) using Beckman PA800 plus platform. The mixture of 5% Pharmalyte 8-10.5 and 1% Pharmalyte 3-10 was used to overcome the limitation of using single Pharmalyte 3-10 in detecting charge heterogeneity of basic mAb. This approach largely improved the resolution of the heterogeneous peaks. In addition, 3 M urea and 50 mM arginine (Arg) were used to improve the separation as solubilizer and cathodic stabilizer, respectively. Under optimized condition, both acidic and basic peaks of the mAb were separated well. Method qualification results showed good specificity, precision, and linearity within the concentration range of 0.03-0.20 mg/mL for mAb R1. The method was then used for C-terminal lysine (Lys) variants characterization and glycosylation profiles analysis. Furthermore, it also had a wide application in the clone screening process. The highly sensitive and repeatable results highlighted the wide application prospects of this method in biopharmaceutical industry.     

技术壁垒对我国装备制造业影响的GTAP模型分析

作为"世界工厂"的中国,已连续5年保持世界第一制造业大国的地位.装备制造业作为制造业的核心,逐渐发挥出推动国民经济发展的基础性作用,同时引导着制造业的整体转型升级进程.但在全球经济复苏缓慢的背景下,发达国家兴起的"再工业化"浪潮和发展中国家对本国装备制造业企业的保护加速了技术壁垒在全球范围内的扩散.作为新型非关税壁垒代表的技术壁垒,凭借其双重性、隐蔽性和多样性,对我国装备制造业的发展造成影响.利用GTAP模型,分别模拟5%、10%和20%幅度下的技术壁垒提高对我国装备制造业各产业的产出、贸易量的冲击,并依据模拟结果提出装备制造业应对技术壁垒的建议.     

特种设备安全科技现状与展望

从法规标准、信息化、安全检测监测技术、安全评定、寿命预测与风险评估、事故应急决策及抢险技术等方面分析了我国特种设备安全科技面临的形势,提出了特种设备安全科技中长期发展思路、发展目标和主要任务,介绍了"十一五"国家科技支撑计划项目《生命线工程和特种设备安全保障关键技术与工程示范》的总体目标、研究内容、课题设置方案、技术难点和创新点及技术路线。