细胞色素C在阴离子修饰的盐桥支撑双层类脂膜上的电化学行为及其应用

采用循环伏安法研究了细胞色素C在月桂酸阴离子修饰的盐桥支撑双层类脂膜上的氧化还原反应;对盐桥支撑双层类脂膜的特性、细胞色素C的电化学反应动力学以及有关影响细胞色素C循环伏安行为各种因素进行了详细探讨;并对用该双层类脂膜体系电化学测定细胞色素C进行了初步尝试。     

DFT Study on the Bilayer Pentaprismane C15H10

1INTRODUCTIONInrecentyears,agreatnumberofachievementshavebeenacquiredforthemoleculeswithcage-likestructures,suchasfullerenesandpolyhedralhydro-carbon.Pentaprismane,firstlysynthesizedbyEaton,OrandBranca[1]in1981,isatypicalpolyhedralhy-drocarbon.Owingtoitssymmetricalandstrainedstructure,manystudiesincludingMM2andMM3molecularmechanicscalculations[2,,semi-empiri-3]calMNDOandAM1molecularorbitalcalcula-tions[4],abinitioHFcalculations[5～7]andDFTcal-culation[8]havebeencarriedoutonit.Recen…     

直流偏压对于在玻碳电极上双层类脂膜成膜过程的影响

应用循环伏安法和电化学阻抗谱研究了直流偏压对卵磷脂在玻碳电极表面自组装成膜过程及其结构的影响.实验发现:无论在正偏压还是负偏压条件下,卵磷脂在玻碳电极上均可组装成膜.施加正偏压时,由于玻碳电极表面所带的正电荷与卵磷脂端基之间的静电作用,使得卵磷脂在电极表面倾向于形成双层的类脂膜,并在0.4V偏压下电极阻抗达到最大值.继续增大电极正向偏压,s-BLM缺陷增加,以至趋于被击穿.提出了适宜的等效电路,并据此非线性拟合电极过程,求得部分阻抗的模型参数.研究发现:膜电容和电荷传递电阻呈现良好的互补效应.     

Topological Lifshitz transition and novel edge states induced by non-Abelian SU(2) gauge field on bilayer honeycomb lattice

We investigate the SU(2) gauge effects on bilayer honeycomb lattice thoroughly. We discover a topological Lifshitz transition induced by the non-Abelian gauge potential. Topological Lifshitz transitions are determined by topologies of Fermi surfaces in the momentum space. Fermi surface consists of N = 8 Dirac points at π-flux point instead of N = 4 in the trivial Abelian regimes. A local winding number is defined to classify the universality class of the gapless excitations. We also obtain the phase diagram of gauge fluxes by solving the secular equation. Furthermore, the novel edge states of biased bilayer nanoribbon with gauge fluxes are also investigated.     

非支撑磷脂双层膜制备及温度对其力学性质的影响

结合聚苯乙烯球刻蚀和微机电系统技术加工氮化硅纳米多孔膜, 并在其上用囊泡法制备非支撑磷脂双层膜, 通过温控原子力显微术(AFM)的成像模式和力曲线模式对非支撑磷脂双层膜的形貌和力学性质进行研究. 实验结果表明, 该方法制备的非支撑磷脂双层膜具有流动性, 能进行自我修复, 该特点有利于提供足够的非支撑磷脂双层膜区域用于其性质研究; 非支撑磷脂双层膜的膜破力和粘滞力均随着温度的升高而减小, 即膜的机械稳定性随着温度的升高而降低. 非支撑磷脂双层膜膜破力小于支撑磷脂双层膜的膜破力, 并且非支撑磷脂双层膜粘滞力随温度的变化趋势与支撑磷脂双层膜的变化趋势相反.     

双层表面活性剂分散制备水基磁流体

Fe₃O₄ magnetic particles were synthesize by chemical co-precipitation. Sodium oleate and poly(ethylene glycol)-4000 were used as bilayer surfactants to envelope the ultra-fine Fe₃O₄ particles. Then stabilized water base magnetic fluid was obtained. Experiments indicated that surfactants and pH value of the solution had great effect on the stability and size of the magnetic fluid when Fe₃O₄ particles were synthesized and enveloped. It was the first time to employ this method to prepare magnetic fluid. Using laser diffraction particle size analyzer we found that the average diameter of magnetic fluid was lessen than 84 nanometer. Its magnetization was measured on magnetic balance and the result amounted to 3.84×10³A·m^-1. Further more， XRD and IR analysis measurements were employed to substantiate the existence of Fe₃O₄ and surfactant structure. The magnetic fluid can be used as tar-geted-part of nanometer targeted drug delivery system.     

Computer simulation of interfacial polarization in stratified dielectric systems

Time and frequency dependent dielectric properties of bilayer dielectrics are treated with components showing dielectric relaxation. The time dependent behaviour can be calculated using the Boltzmann superposition principle. The exact integro-differential equations are derived, and the boundary conditions discussed. The analytical formulae resulting for the frequency domain are an extension of those published for bilayer dielectrics with nonrelaxing components. For the time domain the numerical solution is preferred because the analytical solution is very complicated. After a short discussion of the numerical method some examples are presented, and the effect of various component parameters on the dielectric properties is studied.The main conclusion is that two types of interfacial polarization mechanisms must be distinguished: the classical ohmic, and the dielectric. The latter is the consequence of the polarizational surface charge density, and influences strongly the observed relaxation strengths of the components.Presented at the 20. Jahrestagung Organische Festkörper, July 1983, Brandenburg, German Democratic Republic     

Fluorescence Probing of Cell Membranes with Azacrown Substituted Ketocyanine Dyes

The three dyes with similar fluorescence properties but different lipophility—azacrown- and di-methylamino-substituted ketocyanines—are proposed as probes for the studies of biomembrane structure and dynamics. Their attractive feature is an extremely strong solvatofluorochromism, covering the range from 470 to 650 nm. Two photophysical mechanisms are responsible for these features, the general polarity effect associated with substantial increase of the probe dipole moment on electronic excitation and the excited-state stabilization due to hydrogen bonding to the central carbonyl groups. On the binding of these probes with erythrocyte membranes, three components in fluorescence spectra are resolved. They are attributed to probe molecules bound in two discrete types of binding sites inside the membrane: hydrophilic polar sites, in which carbonyl groups of the probes molecules are hydrogenbonded with hydrogen donor surrounding, and hydrophobic non-polar sites. The third component present in the emission spectra was attributed to the unbound probe in the near-membrane aqueous phase. Our results suggest that such a complex response of the probes is sensitive to the dynamics of hydration of the membrane interior, and this feature can be easily studied in simple ratiometric measurements. Among three studied compounds containing two crown-, two dimethylamino-, or both crown- and diethylamino- substituents, the latter proves to be most prospective in biomembrane research. This probe was tested in monitoring the phase transition of human erythrocyte membrane.     

Electrochemical rectification at electrode surface modified with poly (acrylic acid) and decane thiol

Gold surface modified with a two-component system consisting of poly (acrylic acid) (PAA) by electropolymerizing acrylic acid (AA) and decane thiol (DT), further functionalized with ferrocene monocarboxylic acid (FMC) through covalent linkage, was used to demonstrate mediated electron transfer resulting in a unidirectional flow of current. The electrode surface was modified using two different configurations. In Configuration 1 (Config. 1), electrode surface modified with FMC showed rectification behavior when contacted with a solution containing methylene blue (MB). In Configuration 2, redox-active bilayer was constructed using polyvinyl pyrollidone (PVP) and hexaamineruthernium (II) chloride [Ru(NH₃)₆]²⁺ showed rectification characteristics. The continuous rectification property of the redox-active bilayer is achieved by releasing the trapped [Ru(NH₃)₆]³⁺ in the outer layer using a reductant (ascorbic acid). Spectroelectrochemical measurements were made to study the reduction property of the ascorbic acid. Atomic force microscopic images and impedance measurements were also made on the modified electrode surfaces to explore the compactness of the first layer (PAA and PAA/DT).     

氧化锡和氧化锌双层薄膜的XPS研究

用XPS法研究了SnO2 /ZnO及ZnO/SnO2 双层膜中锌和锡的扩散情况 ,结果表明 :锌在SnO2中的扩散比锡在ZnO中的扩散更容易。讨论了锌在SnO2 层中的扩散方式和扩散的结果。在ZnO层留下了较多的氧 ,并使部分的SnO2 还原为SnO。