General strategy for a short and efficient synthesis of 3-hydroxy-4-methylprolines (HMP)

The non-proteinogenic amino acid 3-hydroxy-4-methylproline (HMP) is an active constituent of some potent antimicrobials including echinocandins, nostopeptins, pneumocandins, sporiofungin and mulundocandins. A synthesis has been achieved in 10 steps with 29% overall yield; the Evans’ aldol reaction using Crimmins’ modified method was pivotal to the success of the strategy.     

Two-component model of solar plages

By use of the 2-m Mcmath-Pierce telescope at Kitt Peak, the high-quality spectra of a plage with moderate brightness near the center of solar disk were obtained. The data include seven spectral lines, which are Hα, Hβ, CaII H and K lines and the infrared triplet. With the consideration of fine structures of solar plages, a two-component atmospheric model is constructed by keeping the cool component to be the quiet atmosphere. Three cases of the hot component are given for different filling factors where the temperature and density distribution are adjusted in order to reproduce the seven observed spectral profiles. We also briefly discuss the influence of the column density at the base of the corona, m0, and the macro-turbulent velocity on the required filling factor and computed profiles. The two-component model is compared with precious one-component semi-empirical models. The limitation of the model is pointed out and further improvement is indicated.     

分子聚集理论在医药学研究中的应用

本文利用聚集型状态方程，克拉贝龙方程以及临界条件推出聚集活性参量方程．分析结果表明，医药的药理活性是可以用聚集活性参量予以定量表征．本文给出了某些医药的主要的药物成分，如氧化亚氮 乙醚、氯仿和水杨酸甲酯等嘛醉剂），一氧化氮（硝酸甘油）、乙醇胺（医药活性剂）和多巴胺（神经递质）的生物活性数据．实践经验表明，这些化学品分别在生命体的心血管系统、神经系统和免疫系统中起着重要的药理功能作用．这表明，本文研究的内容在医药学研究领域有其重要意义．     

Potential formation and high density plasma production on the tandem mirror GAMMA 10

GAMMA 10 experiments have advanced in high density experiments after the last EPS Workshop where we reported high density plasma production by using an ion cyclotron range of frequency heating at a high harmonic frequency and neutral beam injection in the central cell. Recently a high density plasma was obtained with much improved reproducibility than before and without degradation of diamagnetic signal. The high density plasma was attained by adjusting the spacing of the conducting plates installed in the anchor transition regions. Dependencies of particle confinement time, ion energy confinement time and plasma confining potential on plasma density were obtained for the first time in the high density region. Presented at 5th Workshop “Role of Electric Fields in Plasma Confinement and Exhaust”, Montreus, Switzerland, June 23–24, 2002.     

Discretization of the solutions to Poisson’s equation

Sharp estimates (in the power scale) are obtained for the discretization error in the solutions to Poisson’s equation whose right-hand side belongs to a Korobov class. Compared to the well-known Korobov estimate, the order is almost doubled and has an ultimate value in the power scale.     

Application of Hilbert＇s Projective Metric on Symmetric Cones

Let Ω be a symmetric cone. In this note, we introduce Hilbert＇s projective metric on Ω in terms of Jordan algebras and we apply it to prove that, given a linear invertible transformation g such that g（Ω） = Ω and a real number p, ｜p｜ 〉 1, there exists a unique element x ∈ Ω satisfying g（x） = x^p.     

ω-meson photoproduction on nucleons in the near-threshold region

The European Physical Journal A - The ω-meson photoproduction, γ + p→p + ω, is studied in the framework of a model, containing π-meson exchange in t-channel and...     

Electrical properties of neodymium doped CaBi4Ti4O15 ceramics

Neodymium doped bismuth layer structure ferroelectrics (BLSFs) ceramics CaBi_4−xNd_xTi₄O₁₅ (x=0, 0.25, 0.50, 0.75) were prepared by solid-state reaction method. X-ray diffraction pattern showed that single phase was formed when x=0-0.75. The refined lattice parameters showed that a (b) axes decrease at x=0.25 and increase with more Nd³⁺ dopant. The effects of Nd³⁺ doping on the dielectric and ferroelectric properties of CaBi₄Ti₄O₁₅ ceramics are studied. Nd³⁺ dopant decreased the Curie temperature linearly, and the dielectric loss, tan δ, as well. The remnant polarization of Nd³⁺ doped CaBi₄Ti₄O₁₅ ceramics was increased by 80% at x=0.25, while more Nd³⁺ dopant decreased the remnant polarization. CaBi_3.75Nd_0.25Ti₄O₁₅ ceramics had the largest piezoelectric constant d₃₃. The structure and properties of CaBi_4−xNd_xTi₄O₁₅ ceramics showed that Nd³⁺ may occupy different crystal locations when Nd³⁺ content x is less than 0.25 and more than 0.50.     

SPME-GC-MS快速分析炼油厂废水中痕量VOCs

采用固相微萃取-气相色谱-质谱联用(SPME-GC-MS)对炼油厂废水中痕量挥发性有机化合物(VOCs)进行了定性分析,简化了预处理过程,总分析时间为1h左右.对比处理前后的废水样品的MS定性结果,为废水处理工艺的评价以及有机物降解机理提供了依据.     

Synthesis of 2-pyrone-4-carboxaldehydes from acetylene dicarboxaldehyde monoacetal

Reaction of acetylene dicarboxaldehyde monoacetal with substituted Meldrum’s acid leads good yields in 2-pyranones-4-carboxaldehydes substituted in position 3.