全文获取类型
收费全文 | 1905篇 |
免费 | 117篇 |
国内免费 | 181篇 |
专业分类
化学 | 2119篇 |
晶体学 | 6篇 |
数学 | 1篇 |
物理学 | 77篇 |
出版年
2024年 | 1篇 |
2023年 | 51篇 |
2022年 | 16篇 |
2021年 | 30篇 |
2020年 | 39篇 |
2019年 | 43篇 |
2018年 | 49篇 |
2017年 | 41篇 |
2016年 | 58篇 |
2015年 | 63篇 |
2014年 | 104篇 |
2013年 | 258篇 |
2012年 | 111篇 |
2011年 | 138篇 |
2010年 | 97篇 |
2009年 | 118篇 |
2008年 | 120篇 |
2007年 | 113篇 |
2006年 | 106篇 |
2005年 | 88篇 |
2004年 | 92篇 |
2003年 | 78篇 |
2002年 | 76篇 |
2001年 | 31篇 |
2000年 | 37篇 |
1999年 | 24篇 |
1998年 | 28篇 |
1997年 | 25篇 |
1996年 | 22篇 |
1995年 | 22篇 |
1994年 | 20篇 |
1993年 | 16篇 |
1992年 | 12篇 |
1991年 | 10篇 |
1990年 | 12篇 |
1989年 | 9篇 |
1988年 | 11篇 |
1987年 | 4篇 |
1986年 | 1篇 |
1985年 | 6篇 |
1984年 | 3篇 |
1983年 | 1篇 |
1982年 | 3篇 |
1981年 | 6篇 |
1980年 | 5篇 |
1979年 | 2篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1972年 | 1篇 |
排序方式: 共有2203条查询结果,搜索用时 78 毫秒
91.
I. B. Dzvinchuk 《Chemistry of Heterocyclic Compounds》2007,43(4):474-479
The reactions of p-(dimethylamino)benzaldehyde with 5-amino-3-methyl-1-phenylpyrazole and 2-RCOCH2-1H-benzimidazoles have produced 5-(1H-benzimidazol-2-yl)-1H-pyrazolo[3,4-b]pyridines. The transformation includes the formation
of compounds in accordance with a Hantzsch reaction containing a 1,4-dihydropyridine ring, and is completed by the aromatization
either by the splitting off of N,N-dimethylanyline or oxidation. The splitting is produced by acetic acid and the oxidation
by a nitrocompound.
__________
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 578–584, April 2007. 相似文献
92.
Janine Cossy Haja Rakotoarisoa Philippe Kahn Jean-Roger Desmurs 《Tetrahedron letters》1998,39(52):3240-9674
The synthesis of functionalized 2,2-disubstituted 2H-1-benzopyrans was achieved by condensing 2,3,5-trimethylhydroquinone (TMHQ) with ,β-unsaturated aldehydes or ,β-unsaturated acetals under acidic conditions. 相似文献
93.
Biswanath Das Maddeboina Krishnaiah Keetha Laxminarayana K. Ravinder Reddy 《Journal of molecular catalysis. A, Chemical》2007,270(1-2):284-288
Sulfated zirconia has been employed as an efficient recyclable catalyst for the preparation of various β-acetamidoketones or esters at room temperature. The process involves the one-pot multicomponent reactions of aromatic aldehydes, enolizable ketones or β-ketoesters and acetonitrile in the presence of acetyl chloride. 相似文献
94.
《Arabian Journal of Chemistry》2022,15(12):104330
The present study was carried out to design and synthesize a number of novel aromatic carboxamide derivatives of dehydroabietylamine. The preliminary antifungal assay indicated that most of title compounds displayed moderate to good antifungal activity toward the six fungal strains in vitro. Compounds 3i, 3q, 4b and 4d showed significant antifungal activity against Sclerotinia sclerotiorum, with EC50 values ranging from 0.067 ~ 0.393 mg/L. Compounds 3i, 4b and 4d also showed pronounced mycelial growth inhibition activities against B. cinerea and A. solani. Furthermore, in the in vivo assay, compound 4b exhibited brilliant protective activity against S. sclerotiorum-infected rape leaves. Meanwhile, the in vivo bioassay on tomato plants infected by B. cinerea showed that compound 3i and 4d displayed excellent protective activity at 200 mg/L, which were near to boscalid. Primary mechanistic study revealed that 4b could inhibit sclerotia formation as well as reduce the exopolysaccharide level. SEM and TEM analysis indicated that 4b possessed a strong ability to destroy the surface morphology of mycelia, cell structure and seriously interfere with the growth of the fungal pathogen. In addition, 4b exhibited good inhibitory activity (IC50 = 23.3 ± 1.6 μM) toward succinate dehydrogenase (SDH). Molecular modeling study confirmed the binding modes between compound 4b and SDH. The above antifungal results and fungicidal mechanism study revealed that this class of dehydroabietylamine derivatives could be potential SDH inhibitors and lead compounds for novel fungicides development. 相似文献
95.
Abstract In a reexamination of some data on the inhibition of carbonic anhydrase (CA) isozymes I and II by some phenyl and pyridyl substituted sulfanilamide Schif's bases we have found that activity can better be explained by considering the directions of the nodes in π-like near frontier orbitals in the molecules. The near-frontier orbitals involved are those that are analogous to the degenerate pairs of HOMO and LUMO orbitals of benzene. This effect seems common in compounds which contain variously substituted benzene rings and is probably critical to understanding the activity of any aromatic molecule which is bound to its receptor by π–π charge transfer interactions. 相似文献
96.
A facile,one-pot synthesis of N-aryl propargylamine from aromatic boronic acid,aqueous ammonia,and propargyl bromide has been achieved under microwave-assisted conditions.The reactions can be smoothly completed within a total 10 min through a two-step procedure,including copper-catalyzed coupling of aromatic boronic acids with aqueous ammonia and following propargylation by propargyl bromide. 相似文献
97.
98.
Computational insight into asymmetric uranyl‐salophen coordinated with α, β‐unsaturated aldehydes and ketones 下载免费PDF全文
Wen‐Bo Lan Xiao‐Feng Wang Li‐Ping He Yan‐Bin Meng Jun Li Bin Qiu Chang‐Ming Nie 《应用有机金属化学》2018,32(3)
The study of the catalytic activity and activation mechanism of asymmetric uranyl‐salophens with α, β‐unsaturated aldehydes or α, β‐unsaturated ketones, is a research hotspot. In this paper, the complexes of the uranyl–salophen(U‐S) modified by unilateral benzene, coordinated with cyclohexenone, cyclopentenone and acrolein, were investigated using density functional theory calculations at the level of B3LYP/6‐311G(d, p) basis set. The results showed that the uranyl‐salophen(U‐S) weakened the large π bond between C = C and C = O of the α, β‐unsaturated aldehydes and ketones, making the unsaturated aldehydes and ketones activated. In addition, the molecular‐recognition selectivity of the asymmetrical uranyl‐salophen for cyclohexenone and cyclopentenone were much higher than for acrolein. 相似文献
99.
A facile, one-pot synthesis of new phenanthridine derivatives by a three-component reaction between phenantridine, dialkyl acetylenedicarboxylates(DAADs), and aromatic aldehydes is described. The reaction is characterized by mild conditions, high selectivity, and tolerance to various functional groups. 相似文献
100.
Co (II)‐C12 alkyl carbon chain multi‐functional ionic liquid immobilized on nano‐SiO2 nano‐SiO2@CoCl3‐C12IL as an efficient cooperative catalyst for C–H activation by direct acylation of aryl halides with aldehydes 下载免费PDF全文
Nano‐silica supported ionic liquids composed of alkyl carbon chain and transition metal chlorides anions have been prepared and successfully applied as a heterogeneous catalyst in the direct aldehyde C‐H activation. Catalytic results indicated that nano‐SiO2 supported ionic liquid consisting C12 alkyl carbon chain and CoCl3 anion nano‐SiO2@CoCl3‐C12IL showed excellent catalytic properties with good to excellent yields towards the desired aryl ketones. The excellent recyclability of the supported catalyst, mild reaction conditions, low catalyst loading, and operational simplicity are the important features of this methodology. 相似文献