排序方式: 共有33条查询结果,搜索用时 46 毫秒
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Huan Chen Dr. Shengliang Li Dr. Min Wu Dr. Kenry Zhongming Huang Prof. Chun-Sing Lee Prof. Bin Liu 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2020,132(2):642-646
Traditional photosensitizers (PSs) show reduced singlet oxygen (1O2) production and quenched fluorescence upon aggregation in aqueous media, which greatly affect their efficiency in photodynamic therapy (PDT). Meanwhile, non-targeting PSs generally yield low efficiency in antibacterial performance due to their short lifetimes and small effective working radii. Herein, a water-dispersible membrane anchor (TBD-anchor) PS with aggregation-induced emission is designed and synthesized to generate 1O2 on the bacterial membrane. TBD-anchor showed efficient antibacterial performance towards both Gram-negative (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). Over 99.8 % killing efficiency was obtained for methicillin-resistant S. aureus (MRSA) when they were exposed to 0.8 μm of TBD-anchor at a low white light dose (25 mW cm−2) for 10 minutes. TBD-anchor thus shows great promise as an effective antimicrobial agent to combat the menace of multidrug-resistant bacteria. 相似文献
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Muhammad Rabnawaz Guojun Liu 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2015,127(22):6616-6620
Clear anti‐smudge coatings with a thickness of up to tens of micrometers have been prepared through a graft‐copolymer‐based approach from commercial precursors. The coatings repel water, diiodomethane, hexadecane, ink, and an artificial fingerprint liquid. In addition, they can be readily applied onto different substrates using different coating methods. These coatings could find applications in protecting hand‐held electronic devices from fingerprints, windows from stains, and buildings from graffiti. 相似文献
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Qian Xu Sigen A Manon Venet Yongsheng Gao Dezhong Zhou Wei Wang Ming Zeng Chiara Rotella Xiaolin Li Xi Wang Jing Lyu Brian J. Rodriguez Wenxin Wang 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2019,131(31):10726-10730
Further to conventional linear, branched, crosslinked, and dendritic polymers, single chain cyclized/knotted polymers (SCKPs) have emerged as a new class of polymer structure with unique properties. Herein, the development of bacteria‐resistant SCKPs is reported and the effect of this structure on the resistance of polymer materials to bacteria is investigated. Four SCKPs were synthesized by reversible addition fragmentation chain transfer (RAFT) homopolymerization of multivinyl monomers (MVMs) and then crosslinked by UV light to form SCKP films. Regardless of MVM type used, the resulting SCKP films showed much higher resistance to bacteria, and up to 75 % less bacterial attachment and biofilm formation, in comparison with the corresponding non‐SCKP films. This is due to the altered surface morphology and hydrophobicity of the SCKP films. These results highlight the critical role of the SCKP structure in enhancing the resistance of polymeric materials to bacteria. 相似文献
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Haotian Bai Huanxiang Yuan Chenyao Nie Bing Wang Fengting Lv Libing Liu Shu Wang 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2015,127(45):13406-13411
A supramolecular antibiotic switch is described that can reversibly “turn‐on” and “turn‐off” its antibacterial activity on demand, providing a proof‐of‐concept for a way to regulate antibacterial activity of biotics. The switch relies on supramolecular assembly and disassembly of cationic poly(phenylene vinylene) derivative (PPV) with cucurbit[7]uril (CB[7]) to regulate their different interactions with bacteria. This simple but efficient strategy does not require any chemical modification on the active sites of the antibacterial agent, and could also regulate the antibacterial activity of classical antibiotics or photosensitizers in photodynamic therapy. This supramolecular antibiotic switch may be a successful strategy to fight bacterial infections and decrease the emergence of bacterial resistance to antibiotics from a long‐term point of view. 相似文献
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Hongxia Wang Yuhua Xue Jie Ding Lianfang Feng Xungai Wang Tong Lin 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2011,123(48):11635-11638