咪唑醋酸盐的制备和物理化学性质及其水和乙醇溶液的电导率

制备了离子液体1-甲基咪唑醋酸盐（[Mim]Ac）,1,3-二甲基咪唑醋酸盐（[Mmim]Ac）和1-乙基-3-甲基咪唑醋酸盐（[Emim]Ac）,分别测定了它们在293.15-338.14 K间的密度、电导率和绝对粘度,计算了相应的摩尔电导率和运动粘度.用最小二乘法分别拟合建立了密度、电导率、摩尔电导率、绝对粘度和运动粘度与温度的函数关系.讨论了咪唑环3位氮原子上烷基链长对以上咪唑醋酸盐五种物理化学性质的影响.在293.15 K测定了[Mim]Ac{或[Mmim]Ac,[Emim]Ac}（1）-H₂O（或EtOH）（2）二元溶液在全浓度范围内的电导导率,计算了对应的咪唑醋酸盐的摩尔电导率.发现无论是水溶液还是乙醇溶液,溶液的电导率和咪唑醋酸盐的摩尔电导率都随着浓度的增加先增大而后减小.同一浓度下,咪唑环3位氮原子上烷基链长增加,相应的溶液电导率和摩尔电导率下降.且水溶液的电导率和摩尔电导率远大于乙醇溶液的.     

Design,Synthesis and Biological Activity of Ethyl 2-（N-Substituted-arylsulfonamido）-2-oxoacetate

Thirteen new ethyl 2-（N-substituted-arylsulfonamido）-2-oxoacetates（3a-3m）, based on the structure of Ketol-acid reductoisomerase（KARI） inhibitor IpOHA, were designed and synthesized. Their structures were established on the basis of ^1H NMR, IR, MS, and elemental analyses. The bioassay result reveals that the structural changes from hydroxyl group on the N atom of IpOHA to arylsulfonyl groups does not enhance the inhibitory activity of the compounds to KARI in vitro. Compounds 3c, 3h, 3k, and 3m are more effective than IpOHA against the monocotyledonous bamygrass at 100 ug/mL in herbicidal tests.     

[Tb(CH_3COO)_3(H_2O)_2]_2的合成及其结构测定

2-羟基吡啶、希土高氯酸盐和乙酸钴在乙腈中反应,制备了九配位化合物[Tb(CH_3COO)_3·2H_2O]_2该晶体为三斜晶系,P~(?)空间群,其晶胞参数为a=8.870(4)(?),b=9.247(1)(?),c=10.586(1)(?),α=65.13(1)°,β=64.43(2)°,γ=62.16(4)°,V=665.97(?)~3,Z=1,F(000)=394。测定了配合物的红外光谱。讨论了它的生成机制。     

稀土与杂环胺双齿配体配合物的研究(Ⅲ)——稀土三氯醋酸盐与2个α,α''''-联吡啶的混配配合物的合成、性质及晶体结构

利用水和有机溶剂的混合溶剂合成了稀土三氯醋酸盐与2种α,α＇-联吡啶的配合物,并进行了表征,还测定了Pr(TCA)_3(bipy)_2的晶体结构。     

CHEMICAL MODIFICATION OF THE SURFACE OF CALCIUM ALGINATE GEL BEADS

The chemical modification of the surface of calcium alginate gel beads (CAGB) via grafting copolymerization with vinyl acetate (VAc) was studied. The optimum reaction conditions with activation and graft copolymerization two steps were explored. First, 5 grams CAGB with 2.5 mm initial diameter was initiated with 0.0493 mol/L K2S208 at 51℃ for 30 min in 15 mL 1% PVA/H2O. Then 4.34 mol/L VAc was added dropwise and the reaction was allowed to proce at 48℃ for 3 h. The grafting efficiency could come up to 30%. It was found the stability of modified CAGB in the air and in electrolyte solutions was greatly improved.     

Trifluoromethylation of Carbonyl Compounds with Sodium Trifluoroacetate

In the presence of copper （I） halide as catalyst, a variety of carbonyl compounds could be trifluoromethylated with sodium trifluoroacetate to give the corresponding alcohols in moderate to high yields.     

研究部分揭示酒精成瘾机制

<正>来自中国科学院武汉物理与数学研究所徐富强课题组的一项最新研究成果,直观地揭示了酒精作为能源物质直接参与大脑的代谢过程,部分解释了酒精成瘾机制。相关论文日前发表于美国《国家科学院院刊》。据论文第一作者、课题组成员、副研究员王杰介绍,进入体内的酒精,约10%通过呼吸和体液被排出体外,其余90%经过肝脏转化为醋酸盐,成为可被利用的能源物质。近年来,在人体和动物上的研究表明,长期饮酒或酒精成瘾可明显地降低大脑葡萄糖的代谢速率。但大脑能否利用酒精及其代谢物作为能源物质、大脑内醋酸盐类的来源等都是悬而未决的问题。