鱼藤中抗肿瘤活性化合物的追踪分离及与DNA的相互作用

采用活性追踪分离的方法, 从鱼藤中分离鉴定出了2个抗肿瘤活性化合物, 即羟基鱼藤素(1)和鱼藤酮(2). 用丽丝胺罗丹明B(SRB)法评价其抗肿瘤活性, 用紫外光谱和荧光光谱等方法探讨了化合物与DNA的相互作用. 结果发现, 羟基鱼藤素(1)与鱼藤酮(2)为鱼藤的抗肿瘤活性成分, 对人大肠癌细胞HCT8、人肝癌细胞BEL7402、人胃癌细胞BGC823、人肺癌细胞A549和人卵巢癌细胞A2780的半数抑制浓度(IC₅₀) 在0.1~90.0 μmol/L之间. 这两种化合物的紫外吸收强度随着HS-DNA的加入均呈现减色效应, 并使EB-HS-DNA复合体系荧光强度减弱, 表明化合物的抗肿瘤活性与DNA以插入方式作用有关.     

稀土与半胱氨酸、枸橼酸钠三元配合物的合成和抗凝血作用研究

用氯化稀土与枸橼酸钠、半胱氨酸制备了三种组成恒定的稀土三元配合物. 通过元素分析、红外光谱、X射线衍射、摩尔电导、TG-DTA和1H NMR对配合物进行了表征, 并进行了抗凝血试验, 表明稀土三元配合物具有优良的抗凝血性质.     

Energy Spectrum of a Degenerate Fermi Gas at the BEC-BCS Crossover

A theoretical study of the BCS-BEC crossover is presented. Starting from a two-channel Boson-Fermion resonance model, the BCS-Bogoiubov mean-field method and the Green＇s function method are adopted. The result shows that we can end up with a BCS-type theory but with a composite order parameter. Calculation shows that the Bose condensate of BCS Cooper pairs is proportional to the molecular BEC of Bose molecules. The resonance superfluid phase is indicated by the energy spectrum with an obvious interpretation of the transition mechanism.     

The symmetric and antisymmetric superexchange interactions in spin-Peierls system

The influences of Dzyaloshinskii Moriya （DM） interaction and Kaplan-Shekhtman-Entinwohlman-Aharony （KSEA） interaction on the dimerization of a spin-Peierls system are investigated theoretically by using the Lanczos numerical method. The ground state of the spin-Peierls system is still dimerized phase when both of the DM and the KSEA interactions have the same value with Heisenberg interaction. It is found that the KSEA interaction and uniform DM interaction are always against systemic dimerization, but the staggered DM interaction acts in favour of dimerization. Furthermore, the influences of the DM and the KSEA interactions are also studied in terms of the ground state index rate and the energy gap index rate of the dimerized Heisenberg system. The results show that the DM interaction makes the index rates larger, while the KSEA interaction makes them smaller.     

Improving nucleation in the fabrication of high-quality 3D macro-porous copper film through the surface-modification of a polystyrene colloid-assembled template

A new approach is developed to the fabrication of high-quality three-dimensional macro-porous copper films. A highly-ordered macroporous copper film is successfully produced on a polystyrene sphere (PS) template that has been modified by sodium dodecyl sulfate (SDS). It is shown that this procedure can change a hydrophobic surface of PS template into a hydrophilic surface. The present study is devoted to the influence of the electrolyte solution transport on the nucleation process. It is demonstrated that the permeability of the electrolyte solution in the nanochannels of the PS template plays an important role in the chemical electrodeposition of high-quality macroporous copper film. The permeability is drastically enhanced in our experiment through the surface modification of the PS templates. The method could be used to homogeneously produce a large number of nucleations on a substrate, which is a key factor for the fabrication of the high-quality macroporous copper film.     

溶解过程的热效应

溶解热是质-剂微粒间作用(释热)与拆开原先溶质微粒间作用(吸热)、部分溶剂微粒间作用(吸热),在能量方面的代数和,以1 mol溶质溶于大量溶剂(通常是水)计量热效应(kJ/mol)为准。强调“大量溶剂”是因为热效应随溶剂量(在一定范围内)而改变,把1 mol H2SO4、1 mol HCl在水中溶解热和溶剂量的关系列于下表:由H2SO4溶解热前3竖行知:往n(H2SO4)/n(H2O)=1.0/0.5=2.0溶液中加0.5 mol H2O时释热量为:-27.82 kJ/mol-(-15.73 kJ/mol)=-12.09 kJ/mol;若再加0.5 mol H2O,释热量为:-35.90 kJ/mol-(-27.82 kJ/mol)=-8.08 kJ/mol。由HCl(g)溶解热…     

柠檬酸钠对氢氧化镁铝微粒乳化作用的影响

氢氧化镁铝;微粒乳化作用;液体石蜡;柠檬酸钠     

Initial Processes of Sulfur Adsorption on Si（100） Surface

The adsorption of one monolayer S atoms on ideal Si（100） surface is studied by using the self-consistent tight binding linear muffon-tin orbital method. Energies of adsorption systems ors atoms on different sites are calculated. It is found that the adsorbed S atoms are more favorable on B1 site （bridge site） with a distance 0.131 nm above the Si surface. The .S, Si mixed layer might exist at S/Si（100） interface. The layer projected density of states are calculated and compared with that of the clean surface. The charge transfers are also investigated.     

Theoretical Study on the Intermolecular Interactions of Tetrazole Dimers

1 INTRODUCTION Tetrazole and its derivatives are widely applied in the fields of agriculture, biology, chemistry, phar- macology and photographic technology, and they play significant roles in the science and technology as well as national defence[1]. In the past, the res- earches were focused on the molecular geometries, electronic structures, IR, thermodynamic properties, tautomerization, pyrogenation and sensitivity of tetrazole compounds[1～5]. However, study of tetra- zole dimers ha…     

Synthesis and Crystal Structure of the Derivative of Hydroquinone from Mannich Reaction

1 INTRODUCTION Mannich reaction plays an important role in theconstruction of a large variety of nitrogen-containingmolecules, for instance, some pharmaceuticals andnatural products[1, . In practice, phenols and naph- 2]thanols can serve as the substrate of Mannich reac-tion to obtain aminomethylate by the treatment withformaldehyde and amines or nitrogen heterocycliccompounds[3～5]. We report herein the synthesis andcrystal structure of a new nitrogencontaining co…