Synthesis of 5,6-Dihydro-OSW-1 and Its Antitumor Activities

5,6-Dihydro-OSW-1 (1) was synthesized following our previous procedure for the total synthesis of OSW-1. This compound demonstrated slightly stronger potency than that of OSW-1 against the growth of cancer cells.     

法沃尔斯基（FavorskiiAE）重排新进展

本文介绍了近年来法沃尔斯基重排反应在手性药物，立方烷系，杂环衍生物环烷小合成中的最新动态有应用前景。     

聚二甲基二烯丙基氯化铵的合成,表征及抗菌性能

65％的二甲基二烯丙基氯化铵（DADMAC）单体水溶液通过自由基聚合得到分子量约为5000的聚二甲基二烯丙基氯化铵（PDADMAC）均聚物。用红外光谱，核磁共振，X射线衍射仪，粘度法和扫描电镜对PDADMAC进行结构分析和表征。合成聚合物的抗霉菌实验表明，PDADMAC对多种霉菌有抑制作用，具有较宽的抑菌谱；抗细菌实验表明，PDADMAC对金黄色葡萄球菌，大肠杆菌，枯草芽孢杆菌具有不同程度的抑制作用。     

2-碘-N-甲基苯磺酰胺的合成新方法和分子结构

选用新方法合成了2-碘—N-甲基苯磺酰胺，通过^1H NMR,^13C NMR,^13C DEPT NMR(Distortionless Enhancement by Polarization Transfer NMR)和MS确证的其结构。     

The Synthesis of Glycoglycerolipids

A convenient synthetic route was developed for the synthesis of the novel glycolipids: 1,2-di-O-acyl-3-O-(2‘-acylamide-2‘-denxy-ct-D-glucopyranosyl)-sn-glycerols. 10 new compounds of glycolipids with different acyl groups were obtained.     

An Improved Synthesis of Retinoic Acid from β-Ionone

A convenient and large-scale preparation of retinoic acid 1 from β-ionone in five steps with 38% overall yield is described.The key steps are the epoxidization of 2 with a new methylated agent and the condensation 4 with tetraethyl methylenediphophonate in one-pot procedure to prepare 6.     

SYNTHESIS OF MACROPOROUS COPOLYMER OF VCA AND DVB

The reactivity ratios of vinyl acetate(VAc) and divinyl benzene (DVB) were calculated from the Q and e values.The possibility of the copolymerization of these two monomers was predicted and the copolymerization was carried out by suspension polymerization technique in the presence of pore producing agent (toluene and gasoine).The relative ratio of acetoxy group and benzene ring in the copolymer were monitored by IR measurement during the polymerization.The variation of pore properties,such as spectific surface area,porosity and average pore diameter,with polymerization time were determined.The copolymers at various polymerization time were alcoholyzed and thus the variation of the hydroxyl group content with polymerization time was studied.