A New Furost—20（22）—ene Oligoglycoside from Asparagus cochinchinensis

A new furost-20(22)-ene oligoglycoside named as aspacochioside C was isolated from the roots of Asparagus cochinchinensis (Lour.) Merr. Its structure was elucidated to be 26-O-β-D-glucopyranosyl-(25S)-5β- furost-20(22)-en-3β,26-diol-3-O-α-L-rhamnopyranosyl-( 1 →4)-β-D-glucopyranoside on the basis of spectroscopic techniques including 1D and 2D NMR experiments.     

反相离子对液相色谱法分析天冬二肽

提出了一种反相离子对液相色谱法分析天冬二肽的分析技术；采用C18为分析柱，以三氟乙酸为离子对试剂，乙腈-磷酸二氢钾水溶液为流动相；方法不仅适用于天冬二肽产品的纯度分析，而且适用于天冬二肽合成过程中的中间体及副产物的分析；方法具有分析速度快、准确度高、操作简单、实用性强等优点。     

聚天门冬氨酸合成过程中的水解反应

L-天门冬氨酸;;聚天门冬氨酸钠盐;聚丁二酰亚胺;水处理;阻垢作用;聚天门冬氨酸合成过程中的水解反应     

Synthesis and Characterization of Poly （hydroxylethyl, octanediamine）-DL-aspartamide： a New Tissue Engineering Scaffolds

Collagen is the most widely used tissue-derived natural polymer for its goodbiocompatibility and cell adhesion but offers a limited range of mechanical properties1.The construction and properties of synthesized polypeptides are similar to collagen havethe…     

ON CERTAIN CONFIGURATIONS(T)OF FINIKOFF AND THE TRANSFORMATIONS OF CALAPSO

ⅠNTRODUC(?)NIn a recent paper the author has published the result, ofsome,investigations on the periodic sequences of Laplace of periodfour with a stratifiable couple of diagonal congruences.Thedeterinination of these soquences of Laplace requires the integrationof the classical partial differential equation     

新疆保险公司营业大楼大体积筏板基础冬期施工

1996年，商品混凝土在乌鲁木齐还未得到广泛推广应用的情况下，不留施工缝，一次浇筑长65m，宽25m，厚1．6m，防渗等级S8这样大体积筏板基础混凝土，确有一定难度．为此，本文采取了有条件时优先选用商品混凝土，无条件或商品混凝土供应中断时现场搅拌进行浇筑的方法解决了这一难题．     

飞行前恒磁场处理对卤虫卵搭乘我国“8885”卫星后发育的影响

干燥卤虫冬卵预先用300—600×10~(-4)T非均匀恒磁场处理113h,再搭乘我国“8885”卫星飞行8天。飞行完成后第10,31,65和227天进行孵育,观察早期发育速度及孵出能力。结果:(1)卤虫卵受磁场处理后,早期发育速度明显提高;(2)磁场处理会增强卤虫卵对空间飞行不利影响(早期发育延缓及孵出率下降)的耐受力,并促进其从受影响状态下的恢复;(3)磁场处理对卤虫卵所产生的潜在生物学作用是相当持久的,至少在处理后的第318天(飞行后第227天)仍可在发育过程中明显表现出来。     

Investigations on the degradation of aspartame using high-performance liquid chromatography/tandem mass spectrometry

Aspartame is a widely used sweetener,the long-term safety of which has been controversial ever since it was accepted for human consumption.It is unstable and can produce some harmful degradation products under certain storage conditions.A high-performance liquid chromatography/tandem mass spectrometry method was developed for the simultaneous analysis of aspartame and its four degradation products,including aspartic acid,phenylalanine,aspartyl-phenylalanine and 5-benzyl-3,6-dioxo-2-piperazieacetic acid in water and in diet soft drinks.Aspartame and its four degradation products were quantified by a matrix matched external standard calibration curve with excellent correlation coefficients.The limits of detection were 0.16–5.8 mg/L,which exhibited higher sensitivity than common methods.This method was rapid,sensitive,specific and capable of eliminating matrix interferences.It was also applied to the study of the degradation of aspartame at various pH and temperatures.The results indicated that aspartame was partly degraded under strong acidic or basic conditions and the extent of degradation increased with increasing temperature.     

N,O-羧甲基壳聚糖修饰对L-天门冬酰胺酶血浆半衰期及其他性质影响

将具有抗癌作用的L-天门冬酰胺酶用N,O-羧甲基壳聚糖进行化学修饰,以降低酶的抗原性,提高其在体内的半衰期.实验结果表明,修饰酶的表观K_m值与自由酶相差不多,分别为2.6×10~(-4)mol/L和2.2×10~(-4)mol/L(20℃),而抗胰蛋白酶和糜蛋白酶水解能力有很大提高.酶经修饰后抗原性大大降低,且修饰剂分子量越高,降低抗原性的效果越好.自由酶在兔体内的半衰期为1.2h,而修饰酶为40h,提高了33倍.     

功能性高分子聚(羟丙基、丙基)-DL-天冬酰胺的合成、表征及性能的研究

通过改变氨基丙醇和丙胺的投料比，合成了一系列不同侧链的DL-天冬酰胺高分子材料，并改变了材料的亲脂亲水性能。用核磁共振，红外光谱，差热分析，凝胶色谱及吸水性等对高分子材料进行了表征。将模型药物乙酰水杨酸接入系列材料后进行了体外模拟释药性实验，结果表明，脂溶性增加的材料载药后，释药速率明显提高。