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1.
微波消解/ICP-MS法测定不同地点三种马先蒿16种元素 总被引:1,自引:0,他引:1
利用微波消解/ICP-MS法对三种马先蒿中16种元素进行了含量测定,该方法的加样回收率在95%~102%之间,相对标准偏差在1.24%~2.18%之间,具有较高的准确度和精确度。结果表明不同种马先蒿各元素的含量均有所不同,而且不同种马先蒿中各元素与海拔有不同的线性关系。实验结果为马先蒿的药效性和药理、毒理提供理论依据。 相似文献
2.
阿拉善马先蒿(Pedicularis alaschania maxim)系玄参科马先蒿属植物,民间可代替夏枯草入药,主治淋巴结核、淋巴腺炎、高血压和甲状腺肿大等疾病。其化学成分研究尚未见报道。我们从马先蒿中分离得到2个单萜环烯醚甙P1和P2。P2经质谱(FAB MS)、核磁共振谱(~1H和~(13)C NMR)和红外光谱等数据与文献对照确定为桃叶珊瑚甙(aucubin)。P1为一新化合物。本文报道它们的分离与鉴定。 相似文献
3.
马先蒿属植物苯丙素甙成分研究(Ⅰ) 总被引:1,自引:0,他引:1
近年来,由苯丙素和糖组成的苯丙素甙由于具有药理活性而受到人们的重视[1~4].本文报道从穗花马先蒿(Pedicularis spicata)中分得的2个新苯丙素甙,马先蒿甙G(1)和H(2). 相似文献
4.
A new iridoid glycoside 1 and a new iridoid 2 were isolated from the whole plant ofPedicularis kansuensis f. albiflora. Their structures were elucidated by spectroscopic methods. 相似文献
6.
红纹马先蒿中木脂素衍生物成分研究 总被引:1,自引:0,他引:1
红纹马先蒿(Pedicularis striata)是玄参科马先蒿属植物,其主要成分为苯丙素甙。本文报道对该植物进一步研究中分离得到的2个微量甙类化合物,命名为红纹马先蒿甙A和B[Striatoside A(1)和B(2)]。 相似文献
7.
Cheng Shan YUAN Wei Dong XIE Xiu Ping YANG Zhong Jian JIADepartment of Chemistry National Laboratory of Applied Organic Chemistry Lanzhou University Lanzhou 《中国化学快报》2003,(9)
A new iridoid glycoside 1 and a new iridoid 2 were isolated from the whole plant of Pedicularis kansuensis f. albiflora. Their structures were elucidated by spectroscopie methods. 相似文献
8.
Excessive corticosterone (CORT), resulting from a dysregulated hypothalamic–pituitary–adrenal (HPA) axis, is associated with cognitive impairment and behavioral changes, including depression. In Korean oriental medicine, Pedicularis resupinata is used for the treatment of inflammatory diseases such as rheumatoid arthritis. However, the antidepressant properties of P. resupinata have not been well characterized. Here, the antidepressant-like effects of P. resupinata extract (PRE) were evaluated in terms of CORT-induced depression using in vivo models. HPLC confirmed that acteoside, a phenylethanoid glycoside, was the main compound from PRE. Male ICR mice (8 weeks old) were injected with CORT (40 mg/kg, i.p.) and orally administered PRE daily (30, 100, and 300 mg/kg) for 21 consecutive days. Depressive-like behaviors were evaluated using the open-field test, sucrose preference test, passive avoidance test, tail suspension test, and forced swim test. Treatment with a high dose of PRE significantly alleviated CORT-induced, depressive-like behaviors in mice. Additionally, repeated CORT injection markedly reduced brain-derived neurotrophic factor levels, whereas total glucocorticoid receptor (GR) and GR phosphorylation at serine 211 were significantly increased in the mice hippocampus but improved by PRE treatment. Thus, our findings suggest that PRE has potential antidepressant-like effects in CORT-induced, depressive-like behavior in mice. 相似文献
9.
马先蒿属植物苯丙素甙成分研究(Ⅱ) 总被引:1,自引:0,他引:1
马先蒿属(Pedicularis)植物广泛分布于西北和西南地区[1].民间多用其根或茎入药,滋阴补肾[2].本文报道从毛颏马先蒿(P.lasiophrys)中得到的马先蒿甙E(1)和从长花马先蒿(P.longifora)中分得的马先蒿甙Ⅰ(2). 相似文献
10.
Alessandro Venditti Claudio Frezza Fabio Sciubba Sebastiano Foddai Mauro Serafini Marcello Nicoletti 《Natural product research》2016,30(15):1698-1705
We compared the respective metabolite patterns of two Pedicularis species from Dolomites. Seven phenylethanoid glycosides, i.e., verbascoside (1), echinacoside (2), angoroside A (3), cistantubuloside B1 (4), wiedemannioside C (5), campneoside II (11) and cistantubuloside C1 (12), together with several iridoid glucosides as aucubin (6), euphroside (7), monomelittoside (8), mussaenosidic acid (9) and 8-epiloganic acid (13) were identified. Pedicularis verticillata showed also the presence of greatly unexpected secoiridoids, ligustroside (14) and excelside B (15), very rare compounds in Lamiales. Both PhGs and iridoids are considered of taxonomical relevance in the Asteridae and their occurrence in Pedicularis was discussed. In particular, the exclusive presence of several compounds such as 8-epiloganic acid (13), campneoside II (11), cistantubuloside C1 (12), ligustroside (14) and excelside B (15) in Pedicularis rostratocapitata, and angoroside A (3), cistantubuloside B1 (4) and wiedemannioside C (5) in P. verticillata could be considered specific markers for the two botanical entities. 相似文献