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A new indoloquinazoline alkaloid, ophiuroidine 1, having an indolo[2,1-b]quinazoline-6,12-dione skeleton, was isolated from the Caribbean ophiuroid, Ophiocoma riisei. The structure of 1 was determined as 4,8,9-trihydroxyindolo[2,1-b]quinazoline-6,12-dione from spectroscopic data. Ophiuroidine 1 is the first example of an indoloquinazoline alkaloid found in a marine invertebrate. 相似文献
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