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111.
Morsy H. A. Mohammed S. M. Abdel Hamid A. M. Moustafa A. H. El-Sayed H. A. 《Russian Journal of Organic Chemistry》2020,56(1):143-147
Russian Journal of Organic Chemistry - A facile synthesis of a new series of 1,2,3-triazolyl nucleosides via one-pot click reaction is described. Acetylenic nicotinonitriles synthesized previously... 相似文献
112.
Design,Synthesis, and Antifungal Activity of Some New Thiazolo[4,5-d]pyrimidine-5-thione Derivatives
Ghoneim A. A. Bilel H. Moustafa S. M. N. 《Russian Journal of Organic Chemistry》2020,56(12):2148-2152
Russian Journal of Organic Chemistry - A new series of thiazolo[4,5-d]pyrimidine-5-thione derivatives having indole and phenyl moieties were synthesized. Their structures were established by... 相似文献
113.
Selim Rehab E. Ahmed Hanaa H. Abd-Allah Somia H. Sabry Gilane M. Hassan Rasha E. Khalil Wagdy K. B. Abouhashem Nehal S. 《Applied biochemistry and biotechnology》2019,189(1):284-304
Applied Biochemistry and Biotechnology - Acute kidney injury (AKI) is a rapid loss of renal function. It has high mortality rates. Still, renal replacement therapy is considered the best solution... 相似文献
114.
El-Shwiniy W. H. Abbass L. M. Sadeek S. A. Zordok W. A. 《Russian Journal of General Chemistry》2020,90(3):483-488
Russian Journal of General Chemistry - Mononuclear complexes of Co(II), Ni(II), Cu(II), Zr(IV), Pd(II), and Cd(II) with metformin hydrochloride (MF) and 1,4-diacetylbenzene (DAB) have been... 相似文献
115.
Research on Chemical Intermediates - The present investigation involves rapid and efficient synthesis of a series of some novel derivatives for... 相似文献
116.
El-Ahwany M. F. Assy M. G. Sherif M. H. Soliman M. R. 《Russian Journal of General Chemistry》2020,90(3):489-492
Russian Journal of General Chemistry - 2-Aminouracil is used in the synthesis of a new series of tri- and tetracyclic pyrimidine scaffolds as the precursor. Thiazolo[5,4-d]triazolo[4,3-a]pyrimidine... 相似文献
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An efficient and facile protocol for the synthesis of azine and azole ring systems was reported. Whereas, reaction of cinnamoyl isothiocyanate with N-nucleophile containing compounds (namely, p-aminophenol (2), N1-phenylbenzene-1,4-diamine (5) and p-aminoacetophenone (8)) tolerated thiourea derivatives 3, 6, and 9, respectively. The later compounds underwent intramolecular cyclization upon treatment with EtONa to give pyrimidinethiones 4, 7, and 10, respectively, in moderate yield (74–79%). Compound 9 underwent intramolecular cyclization and condensation upon reaction with NaOH and benzaldehyde to give pyrimidinethione 12. Thiosemicarbazides 14 and 19 were obtained through reaction of heteroallen 1 with 2,4-dinitrophenylhydrazine 13 and hydrazone 18, respectively. Compound 14 was cyclized to pyrimidinethione 15 and triazine derivatives 17 through its reaction with EtONa at room temperature and refluxing temperature, respectively. Finally, base mediated and oxidative cyclization of thiourea derivative 19 with EtONa, Br2/AcOH, and Pb(OAc)2 afforded thiadiazole 20, benzothiazolotriazole 21, and triazolethione 22 derivatives, respectively. 相似文献
120.
The starting material 2-furan-2-yl-4-mercapto-6-methylpyrimidine-5-carbonitrile 3 was reacted with various reagents resulting in the formation of a group of new pyrimidines and condensed pyrimidines including quinazoline 6 tetrazolopyrimidine 12, pyrazolopyrimidines 14, 18, and 19, triazolopyrimidine 16, and pyrimidopyridazine 20. The antibacterial activity was evaluated for a group of the synthesized compounds against examples of Gram-positive and Gram-negative bacteria. 相似文献