最小费用原则下的运输路径选择

论述了运输费用的内涵及其构成.运输费用主要包括劳务费、过路费、燃油费、轮胎费,研究了这几种费用的计算方法.并且以吉林省吉林市为起点,以桦甸市为终点,遵循费用最小的原则,分析了运输路径的最佳选择,同时对路径选择的可能原因作出了定性解释.     

氢原子的基态经典振子模型

根据量子力学关于氢原子基态角动量为零的预言，将基态氢原子处理成经典一维振子模型，利用一种带相位因子和斥力项的势函数，给出了基态氢原子的能量及电子振动轨道的解析式。     

煤粉燃烧火焰的三色法温度测量

对彩色 CCD摄像机所拍摄的火焰图像 ,采用三色波长光谱测量法和温度分段线性化的方法来计算煤粉火焰温度 .将火焰温度由高向低分成几个温度段 ,通过温度的标定试验作分段的温度线性化处理 ,再求解由 3个色彩分量和温度标定组成的线性方程组 ,得到较为准确的火焰温度分布 .这种方法准确可靠 ,避免了过去方法中试图用一个标定试验的公式来求解跨度较大的整个温度场分布及由此引起的误差 .最后对一实例进行了计算 ,得到了满意的结果     

Euphorbiasteroid Abrogates EGFR and Wnt/β-Catenin Signaling in Non-Small-Cell Lung Cancer Cells to Impart Anticancer Activity

EGFR and Wnt/β-catenin signaling pathways play a prominent role in tumor progression in various human cancers including non-small-cell lung carcinoma (NSCLC). Transactivation and crosstalk between the EGFR and Wnt/β-catenin pathways may contribute to the aggressiveness of cancers. Targeting these oncogenic pathways with small molecules is an attractive approach to counteract various types of cancers. In this study, we demonstrate the effect of euphorbiasteroid (EPBS) on the EGFR and Wnt/β-catenin pathways in NSCLC cells. EPBS induced preferential cytotoxicity toward A549 (wildtype EGFR-expressing) cells over PC-9 (mutant EGFR-expressing) cells. EPBS suppressed the expression of EGFR, Wnt3a, β-catenin, and FZD-1, and the reduction in β-catenin levels was found to be mediated through the activation of GSK-3β. EPBS reduced the phosphorylation of GSK-3β^S9 with a parallel increase in β-TrCP and phosphorylation of GSK-3β^Y216. Lithium chloride treatment increased the phosphorylation of GSK-3β^S9 and nuclear localization of β-catenin, whereas EPBS reverted these effects. Forced expression or depletion of EGFR in NSCLC cells increased or decreased the levels of Wnt3a, β-catenin, and FZD-1, respectively. Overall, EPBS abrogates EGFR and Wnt/β-catenin pathways to impart its anticancer activity in NSCLC cells.     

快速响应高压电源在KTP晶体极化反转中的应用研究

分析了KTP晶体电导率的特性,设计与研制出一种新型的高压脉冲放大器,可将任意信号发生器产生的信号线性放大,响应速度快,最高输出电压为4000V,最大输出电流为30mA,功率可达100W.用其在KTP晶体上进行多次极化反转实验,取得良好的实验结果.     

Pyrene分子(小片石墨晶体)的电子传导特性

利用量子理论中基于Green函数的tight-binding方法,对pyrene分子的电子传导和电子流分布进行了理论研究。在考虑到界面耦合和Hopping积分的情况下,得出了电子透射谱和流分布的模拟结果。结果显示透射与电子的能量紧密相关;谱的振荡特征是能级量子化的结果;流分布有着特定的方向,并且在每一个原子点上符合Kirchhoff量子流守恒定律。另外还发现了桥接pyrene分子的正负能开关特性。     

一个解决溶剂峰分离的新手段

在凝胶色谱的测试中,由于样品和溶剂的原因,经常会出现溶剂峰.目前,普遍认为,溶剂峰的出现是有两个原因造成的,一是样品中未反应的单体、合成过程中加入的低分子添加剂等小分子的物质,或者一些容易吸潮的样品,吸收了空气中的水份.另外一个原因是凝胶色谱仪器用的流动相的溶剂和溶解样品的溶剂不是同一批号.例如,新出厂的四氢呋喃(THF)试剂,为了防止试剂的氧化,一般都加入一些抗氧化剂.溶剂峰出现的干扰了我们的数据处理的结果.     

Development of a Quantitative Method for Detection of Multiclass Veterinary Drugs in Feed Using Modified QuPPe Extraction and LC–MS/MS

A method was developed for the rapid and quantitative analysis of 30 veterinary drugs belonging to 17 classes (amphenicols (1), anthelmintics (1), cephalosporins (4), coccidiostats (1), lincosamides (1), macrolide (1), nitroimidazole (1), penicillins (3), phenylhydrazines (1), polypeptides (1), pyrethrins (1), quinolones (5), sulfonamides (3), tetracycline (3), neuroleptic agents (1), triazene trypanocidal agents (1), other. (1)) in feeds. The proposed method with a modified Quick Polar Pesticides (QuPPe) sample preparation was validated for the determination of 30 veterinary drugs in feed samples by liquid chromatography triple-quadrupole mass spectrometry (LC–MS/MS). The sample was extracted with methanol containing 1% acetic acid and purified by dispersive solid-phase extraction (d-SPE) with C18. Good linearity (r² ≥ 0.98) was observed, and the LOQ values ranged from 10 to 200 µg/kg. Average recoveries ranged from 70.8 to 118.4%, and the relative standard deviation was ≤ 18.7%. This validated method was used in the determination of 30 veterinary drugs in 142 feed samples obtained from South Korea. The results show that lincomycin was present in only one of the tested feed samples, although it was detected at a value lower than the LOQ. In conclusion, this multi-residue method can be used for screening through the detection and quantitation of residual multiclass veterinary drugs in feed samples.     

林杏琴会堂的音质分析及改进设想

采用精密声级计和双通道声学分析仪，对林杏琴会堂的声场分布、噪声本底和混响时间作了分区测试，应用建筑声学理论对会堂的音质状况进行了分析，并提出改善会堂音质的若干建议．     

关联规则增量式更新的改进算法

关联规则是数据挖掘中的重要研究内容之一，对在事务数据库不变，只对最小支持度和最小可信度进行改变的情况下，针对关联规则的维护问题，设计了一个增量式更新的改进算法AIUA。