Resonance Rayleigh scattering, frequency doubling scattering and second-order scattering spectra of the heparin-crystal violet system and their analytical application

In pH 6.0-11.2 Britton-Robinson buffer solution, binding of heparin with crystal violet (CV) can result in a significant enhancement of resonance Rayleigh scattering (RRS) and resonance non-linear scattering, such as frequency doubling scattering (FDS) and second-order scattering (SOS). Their maximum scattering wavelengths, λ_ex/λ_em, appear at 492 nm/492 nm for RRS, 984 nm/492 nm for FDS and 492 nm/984 nm for SOS, respectively. The optimum conditions of the reaction, the influencing factors and the relationship between the three scattering intensities and the concentration of heparin have been investigated. New methods for the determination of trace amounts of heparin based on the RRS, FDS and SOS methods have been developed. The methods exhibit high sensitivities, the detection limit for heparin is 2.9 ng ml⁻¹ for the RRS method, 3.5 ng ml⁻¹ for the FDS method and 3.3 ng ml⁻¹ for the SOS method. The methods have good selectivity and were applied to the determination of heparin in heparin sodium injection samples with satisfactory results.     

Multiple hydrogen bonds tuning guest/host excited-state proton transfer reaction: its application in molecular recognition

A molecular recognition concept exploiting multiple-hydrogen-bond fine-tuned excited-state proton-transfer (ESPT) was conveyed using 3,4,5,6-tetrahydrobis(pyrido[3,2-g]indolo)[2,3-a:3',2'-j]acridine (1a). The catalytic type 1a/carboxylic acids hydrogen-bonding (HB) complexes undergo ultrafast ESPT, resulting in an anomalously large Stokes shifted tautomer emission (lambdamax approximately 600 nm). Albeit forming a quadruple HB complex, ESPT is prohibited in the noncatalytic-type 1a/urea complexes (lambdamax approximately 430 nm). The HB configuration tuning ESPT properties lead to a feasible design for sensing multiple-HB-site analytes of biological interest.     

对当今艺术设计的思考

设计是一门服务性的大众艺术,已经成为了我们生活的必需,而且人们对设计的要求和看法日趋成熟,作为设计者应该随势而动,重新审视自己,总结设计里程中的得与失.文章从设计的属性入手,重新诠释了设计以人为本,设计为社会服务的精神实质.     

黄芪多糖的提取

改进了传统水煮醇沉从黄芪中提取多糖的方法.在适当的温度进行提取,避免将多种物质同时提出, 使提取物的组成单一.第一次提取物的纯度能达到96％以上,且外观为白色,再经一次提纯后纯度可达到99％ 以上.     

南四湖流域环境地质问题及其治理对策

南四湖流域的各种环境地质问题较突出，如水体污染、矿山环境地质灾害、地下水环境异常、南四湖淤积、地方病等。对流域环境地质问题的治理应综合考虑各种影响因素，建立完善的环境管理体制，增大环境治理投资比例，加强环境治理力度。     

工艺规划中的组合优化问题

为了解决在工艺规划的诸多环节（如工步排序、机床负荷分配、切削参数选择等）普遍存在的组合优化问题，在分析传统方法缺陷的基础上，把一种先进的优化算法——模拟退火算法应用到工艺规划中，并针对加工中心上工步排序这一典型问题，建立组合优化数学模型，对该算法在工艺规划中的运用机理作了详细论述。结果表明，该算法把概率引入到启发式方法中，避免了陷入局部最优点的缺陷，在优化结果和计算时间方面都有明显优于常规方法，有效地提高了工艺规划系统的优化能力。     

应用型工科专业课教学模式的研究

结合材料科学与工程类专业课程建设的内容与效果,探讨了21世纪应用型工科的专业课程所采用的教学方法,提出了“多媒体教学-读书报告-专业实验”三者结合的模式。     

DRDOS攻击及其防范

DOS攻击是一种常见、有效而简单的网络攻击技术,而且DOS攻击的手法也在不断发展,现已出现了威胁更大的DDOS和DRDOS。主要介绍了DDOS和DRDOS攻击的概念和原理,并提出了针对整个系统的防范对策。