Characterization of shock accelerometers using Davies bar and laser interferometer

In this paper, we propose a novel method for evaluating the frequency response of shock accelerometers using Davies bar and interferometry. The method adopts elastic wave pulses propagating in a thin circular bar for the generation of high accelerations. The accelerometer to be examined is attached to one end of the bar and experiences high accelerations of the order of 10³∼10⁵ m/s². A laser interferometer system is newly designed for the absolute measurement of the bar end motion. It can measure the motion of a diffuse surface specimen at a speed of 10⁻³ ∼10⁰ m/s. Uncertainty of the velocity measurement is estimated to be±6×10⁻⁴ m/s, proving a high potential for use in the primary calibration of shock accelerometers. Frequency characteristics of the accelerometer are determined by comparing the accelerometer's output with velocity data of the interferometry in the frequency domain. Two piezoelectric-type accelerometers are tested in the experiment, and their frequency characteristics are obtained over a wide frequency range up to several ten kilohertz. It is also shown that the results obtained using strain gages are consistent with those by this new method. Paper was presented at the 1992 SEM Spring Conference on Experimental Mechanics held in Las Vegas, NV on June 8–11.     

Dynamic response of strain gages up to 300 kHz

Dynamic response of foil strain gages is investigated in the ranges of up to approximately 300 kHz in frequency, 2000 in strain and 750 s^–1 in strain rate. Impulsive input is applied to the gages using elastic wave pulses in a circular bar. The input is determined by measuring the velocity of the bar end with a laser interferometer. It was confirmed that deviations from the static gage factors do not exceed–5 percent within the frequency range up to 45 kHz, 110 kHz and more than 290 kHz for 20-mm, 10-mm and 3-mm gages, respectively, and that the gage length is the dominant factor in the gages' frequency characteristics. This paper also mentions self-generated voltages.     

Hybrid quantum circuit with a superconducting qubit coupled to a spin ensemble

We report the experimental realization of a hybrid quantum circuit combining a superconducting qubit and an ensemble of electronic spins. The qubit, of the transmon type, is coherently coupled to the spin ensemble consisting of nitrogen-vacancy centers in a diamond crystal via a frequency-tunable superconducting resonator acting as a quantum bus. Using this circuit, we prepare a superposition of the qubit states that we store into collective excitations of the spin ensemble and retrieve back into the qubit later on. These results constitute a proof of concept of spin-ensemble based quantum memory for superconducting qubits.     

Fabrication and growth rate estimation of PrBa2Cu3O7−δ single crystal by the modified top seeded crystal pulling method

Recently, we succeeded in fabricating single crystals of PrBa₂Cu₃O_7−δ by a modified top seeded crystal pulling method called the SRL-CP (Solute Rich Liquid-Crystal Pulling) method. Y₂O₃ and MgO polycrystalline crucibles and a MgO single crystal crucible were used to grow the single crystals. The crystal growth temperature was set in the range of 968°C to 972°C. The grown crystals were identified as PrBa₂Cu₃O_7−δ by X-ray diffraction. In the case of using Y₂O₃ crucibles the composition of the grown crystals was Y_xPr_1−xBa₂Cu₃O_7−δ (0.48 < x < 0.57) and in the case of using MgO crucibles a relatively small amount of Mg contamination to the grown crystals occurred at a typical concentration of approximately 1 at.% of the sum of cations. According to the crystal growth model of the SRL-CP method [1–5], a maximum growth rate of 1.7 × 10⁻⁵ cm/s was calculated with the aid of the phase diagram studies we reported earlier [6]. This value is reasonably in agreement with the experimental results.     

Surface Plasmon Resonance of Au Nanoparticles Fabricated by Negative Ion Implantation and Grid Structure toward Plasmonic Applications

Optical properties of Au nanoparticle composites and a grid structure of Cu nanoparticle composite were studied. Negative ion implantation was applied to synthesize Au and Cu nanoparticles in amorphous SiO₂ and Al₂O₃. Au nanoparticles were embedded within a depth of 30 nm by 60keV Au⁻ implantation. The surface plasmon resonance (SPR) of Au:SiO₂ and Au: Al₂O₃ composites shifted to red and to blue, respectively, compared to calculated ones by the Mie theory. Optical nonlinearity was measured with pump-probe femtosecond spectroscopy and the transient spectrum of Au: Al₂O₃ composite presented a large red shift from the SPR peak. Image mapping of far-field transmitted intensity of Cu-implanted SiO₂ with a fine grid structure drawn by laser-lithography was observed by a scanning near-field optical microscopy (SNOM) system.     

Stereoselective synthesis of 1,4-bifunctional compounds by regioselective Pd-catalyzed allylic substitution reaction

[reaction: see text] Highly stereoselective synthesis of 1,4-bifunctional compounds was accomplished via 1,2-asymmetric induction to alpha-oxyaldehyde followed by regio- and diastereoselective Pd-catalyzed allylic substitution reaction.     

Quantum control of molecular chirality: optical isomerization of difluorobenzo[c]phenanthrene

The results of a theoretical study are presented on quantum control of a chiral exchange reaction of a polyatomic molecule by using infrared laser pulses. Difluorobenzo[c]phenanthrene was chosen to be the simplest model for its helical chirality exchange reaction. This molecule has two stable configurations: M and P forms. From the viewpoint of chemical reaction dynamics, isomerization is regarded as the movement of one of the two representative points that initially correspond to the two forms to the position of the other representative point, while the other representative point remains in its initial position. The ground-state potential energy surface and dipole moment functions required to control this reaction were evaluated at the MP2/6-31+G(d,p) and MP2/TZV+(d,p) levels of molecular orbital (MO) theory. An effective potential energy surface (PES) that is a function of twisting motion of the benzene rings and wagging motion of the CF(2) group was constructed on the basis of the MO results. An analytical expression for the effective PES and that for the dipole moment functions were prepared to make the isomerization control tractable. A quantum control method in a classical way was applied to the isomerization of preoriented difluorobenzo[c]phenanthrene in low temperature limits. The time evolution of the representative point of the M form and that of the P form are separately evaluated to determine the optimal laser fields. This means that the laser control produces pure helical enantiomers from a racemic mixture. Representative points are replaced by the corresponding nuclear wave packets in this treatment. The derived control laser field consists of two linearly polarized E(x)() and E(z)() components that are perpendicular to each other. These components are pi-phase-shifted when the representative point is in the transition-state regions. Under the irradiation of this laser pulse, one of the two representative points of the isomerization is transferred to the target position along the intrinsic reaction path between the enantiomers, while the other representative point remains in its initial potential well. This results in one-way isomerization control, that is, the M(P) to P(M) form. The isomerization is completed with yields of ca. 70% within a few picoseconds. Temporal behaviors of the nuclear wave packet whose center corresponds to the representative point are drawn to see how the desired chiral exchange reaction proceeds in the presence of the control field, while its reverse process is suppressed.     

Comparative studies on the antitumor and immunosuppressive effects of the new fluorouracil derivative N4-trimethoxybenzoyl-5'-deoxy-5-fluorocytidine and its parent drug 5'-deoxy-5-fluorouridine

N4-Trimethoxybenzoyl-5'-deoxy-5-fluorocytidine (Ro 09-1390), a new prodrug of 5'-deoxy-5-fluorouridine (5'-dFUrd), was synthesized for the purpose of finding a drug with less intestinal toxicity than the parent compound. The present study compared the antitumor activity and immunotoxicity of Ro 09-1390 with those of 5'-dFUrd, 5-fluorouracil (5-FUra) and tegafur in various transplantable tumor models. The antitumor efficacy of Ro 09-1390 was comparable to 5'-dFUrd and these two agents were much more effective than the others. However, Ro 09-1390 was much less toxic to the intestinal tract and less immunosuppressive in both humoral and cellular immune reactions than 5'-dFUrd. Consequently, Ro 09-1390 showed higher therapeutic indices and higher efficacy than 5'-dFUrd at high dosages. The antitumor spectrum of Ro 09-1390 was somewhat different from that of 5'-dFUrd, though it shows the efficacy after it converts to 5'-dFUrd. The activity of Ro 09-1390 was partly associated with cytidine deaminase in the tumors treated. Ro 09-1390 appeared to be more effective against tumors with a high concentration of the enzyme by which the major metabolite 5'-deoxy-5-fluorocytidine (5'-dFCyd) is metabolized to 5'-dFUrd.     

Total synthesis of the antitumor acetogenin mosin B: desymmetrization approach to the stereodivergent synthesis of threo/trans/erythro-type acetogenins

A total synthesis of the threo/trans/erythro-type acetogenin mosin B and one of its diastereomers has been achieved. The carbon skeleton is assembled in a convergent fashion from two segments (a THF ring segment and a gamma-lactone segment) through the Nozaki-Hiyama-Kishi reaction. The THF ring segment was stereoselectively constructed by a stereodivergent synthesis starting from a common intermediate (4-cyclohexene-1,2-diol) based on a desymmetrization strategy. The gamma-lactone segment was synthesized by coupling a triflate and a chiral alpha-sulfenyl gamma-lactone. By virtue of these synthetic results, we suggest that the absolute configuration of natural mosin B is 1 a. Antiproliferative effects of 1 a and 1 b were also investigated.