4-[(4’-氯苯基)(5-氟-2-羟基苯基)亚甲氨基]丁酸酯类化合物的核磁共振氢谱

γ—氨基丁酸在生理条件下不易透过血脑屏障进入脑组织,为了增大γ—氨基丁酸的脂溶性,使其能透过血脑屏障进入脑组织,作者选用具有较高亲脂性的（4’—氯苯基）（5—氟—2—羟基苯基）甲酮作为γ—氨基丁酸的亲脂性载体,设计并合成了7个4-[（4’—氯苯基）（5—氯—2—羟基苯基）亚甲氨基]丁酸酯类化合物作为抗癫痫化合物进行抗惊厥活性实验,所合成的化合物未见文献报道．合成的样品经元素分析、红外光谱和核磁共振氢谱检测,证实合成的化合物的结构与目标化合物一致．     

Effects of Aqueous and Organic Solvents on the Conformational Properties of the Helix-Forming alpha-Methyl-beta-L-aspartamyl Residue

The conformational preferences of N-acetyl-N'-methyl-alpha-methyl-beta-L-aspartamide, which is the model compound for helical poly(beta-L-aspartate)s, have been determined by ab initio SCF-MO computations. Two driving patterns have been found for the existing 13 minimum energy conformations: (i) intramolecular hydrogen bonding interactions of both amide-amide and amide-ester type; and (ii) repulsive interactions between the four oxygen atoms contained in the molecule. Self-consistent reaction-field (SCRF) calculations based on the method proposed by Miertus, Scrocco, and Tomasi have been performed in order to evaluate the effect of the solvent on the conformational preferences of the compound subject of study. Water and carbon tetrachloride were the solvents chosen for this purpose, and results have been discussed and interpreted on the basis of their electronic structures. The conclusions drawn from this study are of assistance to understand some features of the conformational transitions experimentally found in poly(beta-L-aspartate)s.     

Volumes of activation for dissociation of pentacyanoferrates(II) through pressure and salt effects on reactivity

Summary Dependences of rate constants on pressure (up to 1 kbar) and on added salt concentration (up to 6.0 mol dm^–3 LiNO₃, NaNO₃, NaCl, Na₂SO₄ or KNO₃) have been established for dissociative substitution of pentacyanoferrates(II), [Fe(CN)₅L]^3– with L = 4-cyanopyridine, 4,4-bipyridyl, 4-phenylpyridine and 4-t-butylpyridine. Activation volumes derived directly from pressure effects, and indirectly from salt effects via surface tension dependences and derived surfaces of activation, are reported, compared and discussed.     

镧的植物防病效果及其生物学效应

通过灭菌土接种Rhizoctonia solani以及混合接菌Rhizoctonia solani和Fusarium solani进行盆栽试验,分别研究了镧浸种处理对高羊茅及板蓝根出苗、生长发育的影响。结果表明,镧浸种能明显地减少病原菌的侵染,对由其所造成的种腐、芽腐及根腐等有显著的防治效果,提高了板蓝根和高羊茅种子的出苗率。同时,镧浸种在适当的浓度范围内,还能显著地促进植物的生长发育,生物量明显增加。利用盆栽水稻试验研究了稀土镧对水稻纹枯菌(Rhizoctonia solani)的毒力,测定结果表明,镧喷施于水稻植株上对水稻纹枯病有明显的防治效果,且在活体条件下,喷施镧后1和7 d对水稻纹枯菌(Rhizoctonia solani)的有效中浓度分别为128.7和128.1 mg.L-1,均明显低于离体条件下的有效中浓度(171.9 mg.L-1)。     

用环形扩散管和滤纸联用采样技术采集空气中氨和铵盐

建立了环形扩散管和滤纸采样夹联用，分形态同时采集空气中所态氨和颗粒态铵盐的方法。在同一气流中，采用涂渍１．５％草酸乙醇水溶液的环形扩散管采集气态氨，用浸渍上述试剂的玻璃纤维纸和慢速定量滤纸分别采集颗粒安和第一层滤纸上的铵盐挥发产生的氨气。用靛酚蓝比色法分别测定氨和铵盐。当采气流速为１．０Ｌ／ｍｉｎ时，采样效率高于９８．２％。将本法测得的氨气和铵盐的总量与标准采样方法的测定结果比较。无显著性差异（Ｐ     

茶碱对聚苯胺尿酸酶电极的生物电化学活性的抑制

用聚苯胺尿酸酶电极研究了茶碱对固定酶的影响，结果表明，茶碱对固定尿酶酶有明显的抑制作用，但这种抑制作用是可逆的，在茶碱的存在下，ＰＨ对酶电极的响应电流影响与无茶碱存在时不同；在０．２－０．５Ｖ之间，酶电极的响应电流随电位加而迅速升高，当电位进一步升高时，其变化速度减慢，茶碱使尿酶酶催化反应的活化能从无抑制剂存在的时的２９．９ｋＪ．ｍｏｌ＾－１提高到４７．８ｋＪ．ｍｏｌ＾－１，即抑制剂改变了尿酸催化     

POLYMERIZATION OF OCTAFLUOROCYCLOBUTANE IN GLOW DISCHARGE Ⅱ. ESCA AND IR CHARACTERIZATION OF POLYMER STRUCTURE*

In a capacitively coupled discharge with external electrodes, He, H_2, N_2 or Ar were used as plasmagas, polymerization of octafluorocyclobutane was carried out under different conditions by varyingdischarge power, pressure, plasma gas and plasma-gas/monomer ratio. Structure of polymerizedproducts was characterized by IR spectroscopy and ESCA measurement. It was found that therewere six elements in the products, i.e. C, F, Si, O, N and H. The probably existed groups in poly-mers wer investigated. By analyzing the resolved peaks of C_(1S) region in ESCA spectra, effect of thereaction conditions on degree of branching of the polymerized products and the relationship of thepolymer structure wth the mechanism of the competitive ablation and polymerization process werestudied. In addition, polymer deposition process occurring in glow discharge was discussed.