全文获取类型
收费全文 | 2949篇 |
免费 | 82篇 |
国内免费 | 15篇 |
专业分类
化学 | 2366篇 |
晶体学 | 28篇 |
力学 | 29篇 |
数学 | 199篇 |
物理学 | 374篇 |
综合类 | 50篇 |
出版年
2023年 | 18篇 |
2022年 | 21篇 |
2021年 | 21篇 |
2020年 | 42篇 |
2019年 | 42篇 |
2018年 | 26篇 |
2017年 | 23篇 |
2016年 | 56篇 |
2015年 | 53篇 |
2014年 | 89篇 |
2013年 | 183篇 |
2012年 | 142篇 |
2011年 | 181篇 |
2010年 | 122篇 |
2009年 | 106篇 |
2008年 | 184篇 |
2007年 | 171篇 |
2006年 | 192篇 |
2005年 | 191篇 |
2004年 | 172篇 |
2003年 | 144篇 |
2002年 | 146篇 |
2001年 | 50篇 |
2000年 | 41篇 |
1999年 | 24篇 |
1998年 | 38篇 |
1997年 | 29篇 |
1996年 | 26篇 |
1995年 | 16篇 |
1994年 | 29篇 |
1993年 | 14篇 |
1992年 | 23篇 |
1991年 | 16篇 |
1989年 | 11篇 |
1988年 | 15篇 |
1987年 | 9篇 |
1986年 | 15篇 |
1985年 | 33篇 |
1984年 | 46篇 |
1983年 | 26篇 |
1982年 | 37篇 |
1981年 | 42篇 |
1980年 | 26篇 |
1979年 | 25篇 |
1978年 | 17篇 |
1977年 | 21篇 |
1976年 | 18篇 |
1975年 | 15篇 |
1974年 | 16篇 |
1973年 | 11篇 |
排序方式: 共有3046条查询结果,搜索用时 15 毫秒
951.
Hideyuki Yoshida Fumito Kido Makoto Yoshitake Kenichiro Todoroki Hitoshi Nohta Masatoshi Yamaguchi 《Analytical sciences》2007,23(4):485-488
A liquid chromatographic (LC) determination of catecholamines and indoleamines is described. This is based on intramolecular excimer-forming fluorescence derivatization with 4-(1-pyrene)butanoyl chloride, followed by reversed-phase LC. The analytes, containing an amino moiety and phenolic hydroxyl moieties in a molecule, were converted to the corresponding polypyrene-labeled derivatives by one-step derivatization. They afforded intramolecular excimer fluorescence, which can clearly be discriminated from the normal fluorescence emitted from reagent blanks. The detection limits (S/N = 3) for catecholamines and indoleamines were femto-mole levels per 20-microL injection. Furthermore, this method was applied to a urine assay. 相似文献
952.
953.
Ultrasonic focusing in two dimensions has been investigated by calculating the propagation of ultrasonic pulses through cross-sectional models of human abdominal wall and breast. Propagation calculations used a full-wave k-space method that accounts for spatial variations in density, sound speed, and frequency-dependent absorption and includes perfectly matched layer absorbing boundary conditions. To obtain a distorted receive wavefront, propagation from a point source through the tissue path was computed. Receive focusing used an angular spectrum method. Transmit focusing was accomplished by propagating a pressure wavefront from a virtual array through the tissue path. As well as uncompensated focusing, focusing that employed time-shift compensation and time-shift compensation after backpropagation was investigated in both transmit and receive and time reversal was investigated for transmit focusing in addition. The results indicate, consistent with measurements, that breast causes greater focus degradation than abdominal wall. The investigated compensation methods corrected the receive focus better than the transmit focus. Time-shift compensation after backpropagation improved the focus from that obtained using time-shift compensation alone but the improvement was less in transmit focusing than in receive focusing. Transmit focusing by time reversal resulted in lower sidelobes but larger mainlobes than the other investigated transmit focus compensation methods. 相似文献
954.
Makoto Tamura 《Transactions of the American Mathematical Society》1998,350(5):2129-2140
Feng Luo and Richard Stong introduced the average edge order of a triangulation and showed in particular that for closed 3-manifolds being less than 4.5 implies that is on . In this paper, we establish similar results for 3-manifolds with non-empty boundary; in particular it is shown that being less than 4 implies that is on the 3-ball.
955.
Oba M Endo M Nishiyama K Ouchi A Ando W 《Chemical communications (Cambridge, England)》2004,(14):1672-1673
Photosensitized oxidation of tellurides carrying bulky aromatic substituents afforded the corresponding telluroxides which were found to react with simple alcohols to give the corresponding carbonyl compounds in excellent yields along with the starting tellurides. 相似文献
956.
Comprehensive analysis system using liquid chromatography-mass spectrometry for the biosynthetic study of peptides produced by cyanobacteria 总被引:2,自引:0,他引:2
Microcystins are hepatotoxic heptapeptides and general tumor promoters produced by several species of the genera Microcystis, Anabaena, Oscillatoria and Nostoc. They are non-ribosomally synthesized via a mixed polyketide synthase/non-ribosomal peptide synthetase system called microcystin synthetase. We have carried out the detection, isolation and structural determination of non-toxic peptides produced together with microcystins by toxic cyanobacteria, which are classified into several groups on the basis of their structures and some of these non-toxic peptides are also non-ribosomally synthesized as well as microcystins. In the present study, we tried to correlate the secondary metabolic peptides produced by the hepatotoxic cyanobacteria with the corresponding peptide synthetase genes. An analytical method using LC-electroscopy ionization MS and photodiode array detection was developed for the exhaustive screening of cyanobacterial peptides in Japanese strains and it was successfully applied to the peptide fractions extracted from these strains. The established method was advantageous over conventional ones using the usual HPLC and matrix-assisted laser desorption ionization time-of-flight MS, because more structural information could be obtained and it is easier to distinguish microcystins from other peptides using this method. Small amounts of other peptides could also be detected by this method. The established method will contribute to the investigation of the relationship between genes encoding the peptide synthetase and secondary metabolic peptides. 相似文献
957.
This paper reports a facile method for the preparation of lyso-GM1 [Gal beta1-->3GalNAc beta1--> 4(Neu5Ac alpha2-->3)Galbeta1-->4Glc beta1-->1'-sphingosine] and lyso-GM2 [GalNAc beta1-->4(Neu5Ac alpha2-->3)Gal beta1-->4Glc beta1-->sphingosine], respectively, from GM1 [Galbeta1-->3GalNAc beta1-->4(Neu5Ac alpha2-->3)Galbeta1-->4Glc beta1-->1'-Cer] and GM2[GalNAc beta1-->4(Neu5Ac alpha2-->3)Galbeta1-->4Glc beta1-->1'-Cer], using sphingolipid ceramide deacylase and high performance anion-exchange chromatography (HPAEC). The enzymatically released lyso-GM1 and/or lyso-GM2 was effectively separated from its parent ganglioside by HPAEC using a Mono Q HR 5/5 column with an Amersham Biosciences fast protein liquid chromatography system. The yield was almost quantitative and the separation completed in approximately 3 h. This method is more convenient and effective than the conventional method using alkaline hydrolysis and silicic acid chromatography to generate and purify lyso-gangliosides. 相似文献
958.
A practical method for the allylation of low electrophilic N-aliphatic imines was established by allylic tantalum. This is a superior methodology compared with conventional ones in terms of wide applicability to imines. 相似文献
959.
The crystal orientation of creatine monohydrate varies significantly with tableting performance and pulverizing mechanism. Furthermore, the X-ray diffraction patterns of anhydrous forms of untreated creatine monohydrate and of pulverized creatine monohydrate exhibit different crystal orientations. However, hygroscopic forms of unpulverized creatine anhydrate and pulverized creatine anhydrate was exhibit the same diffraction peak pattern. The hygroscopicity of unpulverized and pulverized creatine anhydrate has been investigated by hydration kinetic methods using isothermal differential scanning calorimetry data. Testing of the hygroscopicity of unpulverized and pulverized creatine anhydrate at various levels of relative humidity (RH) at 25 °C revealed that the anhydrate was stable at less than 33% RH, but was transformed into the monohydrate at more than 52% RH. Hydration data of unpulverized and pulverized creatine anhydrate at 60% and 75% RH were calculated to determine hydration kinetics using various solid-state kinetic models. The hydration type of unpulverized and pulverized creatine anhydrate powder follows the zero-order mechanism (Polany–Winger equation) R1. The transition rate constant of pulverized creatine anhydrate, calculated from the slope of the straight line, was about 1.34–1.36 times higher than that of unpulverized creatine anhydrate. 相似文献
960.
Kaneko T Makino T Miyaji H Teraguchi M Aoki T Miyasaka M Nishide H 《Journal of the American Chemical Society》2003,125(12):3554-3557
A poly(9,10-anthryleneethynylene)-based polyradical with two pendant stable phenoxyls in one anthracene skeleton was newly synthesized via polymerization of the corresponding bromoethynylanthracene monomer using a Pd(0) catalyst. The average molecular weight of the polymer reached M(n) = 5 x 10(3) and was soluble in common organic solvents. The polyradical was prepared from the corresponding hydroxyl precursor polymer and was appropriately stable at room temperature. The ESR spectrum of the corresponding monomeric radical suggested an effectively delocalized spin density distribution on the backbone anthracene. The magnetization and the static magnetic susceptibility of the polyradical were measured using a SQUID magnetometer. The large average spin quantum number (S = (5)/(2)) of the polyradical indicated that the ferromagnetic spin coupling network of the polyradical had spread throughout the pi-conjugated chain and that it was considerably insensitive to spin defects. 相似文献