Quantitative enantiomeric analysis of chlorcyclizine,hydroxyzine, and meclizine by capillary electrophoresis

A simple capillary zone electrophoresis method was developed for the quantitative enantiomeric analysis of piperazine antihistamines with teratogenic suspicion in animals. Enantioseparation of chlorcyclizine, hydroxyzine, and meclizine was performed in glycine buffer (0.6 mol L^-1; pH 3.00) with sulfated -cyclodextrin (5 mg mL^-1) as a chiral selector; and the separated drugs were monitored by ultra-violet detector. The lower quantitation of the individual enantiomer is attainable at 10 µmol L^-1, using an achiral piperazine drug (cyclizine) as internal standard. The method is simple and rapid with a short run time (<5 min) for the analysis of chlorcyclizine, hydroxyzine or meclizine enantiomers.     

Line Intensities of (12)C(16)O(2) in the 1.2-1.4 µm Spectral Region

The 7000-8500 cm(-1) spectral region of (12)C(16)O(2) has been investigated using the high-resolution FT spectrometer of LPPM in Orsay. The two strongest bands in this region are the 10031 <-- 00001 and 10032 <-- 00001 bands centered at 8294 and 8192 cm(-1). Line intensities in these two bands and in the 40013 <-- 00001 and 40014 <-- 00001 bands have been measured. Using the method of effective operators, these line intensities have been included in a new fit of effective dipole-moment parameters to all available experimental data in the same spectral region of (12)C(16)O(2). The corresponding calculated line intensities of the 10031 <-- 00001 and 10032 <-- 00001 bands are compared with the experimental ones. Copyright 2000 Academic Press.     

KDS-CM： A Cache Mechanism Based on Top-K Data Source for Deep Web Query

Caching is an important technique to enhance the efficiency of query processing. Unfortunately, traditional caching mechanisms are not efficient for deep Web because of storage space and dynamic maintenance limitations. In this paper, we present on providing a cache mechanism based on Top-K data source （KDS-CM） instead of result records for deep Web query. By integrating techniques from IR and Top-K, a data reorganization strategy is presented to model KDS-CM. Also some measures about cache management and optimization are proposed to improve the performances of cache effectively. Experimental results show the benefits of KDS-CM in execution cost and dynamic maintenance when compared with various alternate strategies.     

Synthesis and crystal structures of silver(I) complexes of 3(5)-methyl-5(3)-phenyl-1<Emphasis Type="Italic">H</Emphasis>-1,2,4-triazole: two isomeric infinite chains coexisting in the same crystal

Reactions of 3(5)-methyl-5(3)-phenyl-1H-1,2,4-triazole (3-Me-5-Ph-tzH) with AgNO₃ in the absence/presence of NH₃ yield a mononuclear [Ag(3-Me-5-Ph-tzH)₂]NO₃·3H₂O (1) and a polymeric [Ag(3-Me-5-Ph-tz)]_n (2), respectively. Two structurally different infinite chains, however, with the same formula of AgC₉H₈N₃—one is double-decked and the other single zigzag—coexist in 1:1 ratio in the crystal of 2. As far as we know, 2 is the first binary silver(I) complex based on an asymmetric triazole and represents a rare case of two supramolecular isomers coexisting in the same crystal.     

论朱德对丰富毛泽东建党思想的若干思考——纪念建党90周年

目前,朱德建党思想研究多从廉政视角展开,而将其作为独立研究领域进行宏观考察的相对较少,尚需深挖和进行理论规整。朱德作为老一辈无产阶级政党领袖,在革命、建设中对党的建设进行了许多深入思考,有着特色的表述方式：站在＂科学最高成就＂的高度认识马克主义理论指导地位,倡导理论学习与指导的＂一贯性＂与＂发展性＂;以＂站在群众之中＂的政党建设根本利益观作为尺度,倡导党的群众利益观;把发展作为恒久命题,倡导党应领导建立＂革命家务＂和搞好建设;把干部发展作为主线,倡导人才选拔＂眼光向下＂、青年成长重在学习。     

丙烯在镍离子高分散催化剂上反应过程的TPSR EPR XPS UV-DRS研究

用ＴＰＳＲ法对丙烯在硫酸镍高分散型催化剂上反应过程进行考察；用ＮＨ３－ＴＰＤ法对ＮＨ３吸附中心进行跟踪，发现除强弱两类酸中心外，确有第三类活性中心，此第三类活性中心可能就是配位催化活性中心。     

A grid‐like two‐dimensional AgI coordination polymer: poly[[[μ3‐N′‐(4‐cyanobenzylidene)isonicotinohydrazide]silver(I)] perchlorate]

This study presents new coordinating modes of a Schiff base with three coordinating groups and an interesting two‐dimensional framework based on two types of constructing units. In the title compound, {[Ag(C₁₄H₁₀N₄O)]ClO₄}_n, the Ag^I ion is coordinated by three N atoms and one O atom from three different N′‐(4‐cyanobenzylidene)isonicotinohydrazide (L) ligands, forming a primary distorted square‐planar coordination geometry. Two ligands each bridge two metal centres through one carbonitrile N atom in a monodentate mode and the hydrazide N and O atoms in a bidentate mode to form a small centrosymmetric (2+2)‐Ag₂L₂ ring as a principal constructing unit. The pyridyl N atoms from four ligands in four of these small rings coordinate to Ag atoms in adjacent rings to form a large hexanuclear silver grid. A two‐dimensional framework of rectangular grids is constructed from these small rings and large grids. Two perchlorate anions are located in each large grid and are bound to the grid by N—H...O hydrogen bonding. Crosslinking between the layers is achieved through long Ag...O interactions between the perchlorate anions and Ag atoms in adjacent layers.