匹配光纤光栅应力传感器解调技术

设计了一种基于螺旋微进器的匹配FBG应力传感解调方案,进行了理论推导;并进行了匹配光栅应力传感解调试验.试验中完成了1～1 660 N的应力信号的解调.     

川西南永探1井区火山岩储层预测方法及应用

四川盆地西南地区火山岩气藏地质条件十分复杂、岩相变化大、物性变化快、储层非均质性强,地震储层预测面临诸多技术挑战。以永探1井区为研究对象,通过井震标定和正演模拟,确定不同岩相的地震响应特征,通过多属性融合,预测岩相平面分布。基于地震岩石物理分析,明确储层敏感参数,应用叠后地震反演技术,进行敏感参数反演,在此基础上根据岩石物理分析结果将弹性参数转换为储层物性参数,开展储层预测。结果表明,该方法能准确地预测出研究区块目的层火山岩优质储层分布,与实际钻井结果吻合程度高,可为该地区下一步火山岩储层精细描述及生产部署提供指导。     

多弧离子镀制备的耐事故燃料包壳铬涂层晶粒结构研究

本文通过从几十微米到几埃的多尺度表征展示了多弧离子镀制备铬涂层的详细结构.经XRD, SEM, FIB, TEM和HRTEM表征,结果显示该涂层是一种多重结构,包括表面上的微米级颗粒、缺陷带钉扎的微米或次微米级液滴、以堆垛层错为晶界的柱状晶、以刃位错和螺型位错为区分的微晶、位错末端的原子畸变以及原子排列无序化的区域.这些结构通过改变涂层的结晶度,影响了晶格常数、表面粗化和FIB溅射裂纹.此外,通过分析HTEM照片,确定了这些堆垛层错和位错的类型.最后,讨论了沉积参数对这些晶粒结构的影响.     

基于矩阵分析的橡胶透水混凝土正交试验

选取水胶比、橡胶粒径、橡胶掺量、VAE-707乳液掺量及目标孔隙率五个因素对橡胶透水混凝土进行正交试验设计,研究其对抗压、抗折强度及透水性能的影响。利用矩阵分析法和灰色决策进行分析,得到橡胶透水混凝土最优配合比:水胶比0.3、橡胶颗粒大小0.425 mm、橡胶颗粒掺量3%、VAE-707乳液掺量为6%、目标孔隙率为16%;其中目标孔隙率对透水混凝土的性能贡献率最大,透水混凝土的抗压、抗折强度随着目标孔隙率的升高而降低,而透水系数则呈相反规律;透水混凝土实测孔隙率整体小于设计孔隙率,有效孔隙率约占总孔隙率的80%～90%,封闭孔占总孔隙10%～20%左右。     

DEPENDENCE OF DAMPING CHARACTERISTICS OF A BEAM WITH DAMPING RUBBER MAGNETIC POWDER ON RUBBER PROPERTY

A cantilever beam with Damping Material Applying Rubber Magnetic Powder （DRM） has been investigated. Two methods are selected to hold DRM to a vibrating steel beam, one is to attach DRM by the magnetic attractive force （called DRM beam） and the other by adhesive bonding （called AB-DRM beam）. Different from the damping property of AB-DRM beam caused by shear deformation of damping material, the damping property of DRM beam is characterized by the sliding frictional loss together with the internal loss of damping material. The authors established a formulation to predict the damping characteristics of DRM beam, which was validated experimentally. It is found that rubber material loss factor β has a decisive influence on damping improvement of DRM beam versus AB-DRM beam. If β is smaller than the critical value around 0.8255, a valid range of vibratory amplitude always exists in which DRM beam can achieve better damping than AB-DRM beam; conversely, if β is bigger than the critical value, the valid range does not exist when slide occurs. Such results are used to determine the merits and limitations of DRM and develop design guidelines.     

面向对象程序设计的演示教学中的归纳

目前应用多媒体教学越来越广泛,对采用演示可视化方法进行面向对象程序设计的教学时归纳方法的作用作一论述。     

Spectrally distinct near-infrared probes for multiplexed biomedical imaging

Our bodies contain a huge amount of anatomical,physiolo-gical,cellular or molecular information.The understanding of how these pieces of information are organiz...     

Conformational Selection Mechanism Provides Structural Insights into the Optimization of APC-Asef Inhibitors

Metastasis is the major cause of death in colorectal cancer and it has been proven that inhibiting an interaction between adenomatous polyposis coli (APC) and Rho guanine nucleotide exchange factor 4 (Asef) efficaciously restrain metastasis. However, current inhibitors cannot achieve a satisfying effect in vivo and need to be optimized. In the present study, we applied molecular dynamics (MD) simulations and extensive analyses to apo and holo APC systems in order to reveal the inhibitor mechanism in detail and provide insights into optimization. MD simulations suggested that apo APC takes on a broad array of conformations and inhibitors stabilize conformation selectively. Representative structures in trajectories show specific APC-ligand interactions, explaining the different binding process. The stability and dynamic properties of systems elucidate the inherent factors of the conformation selection mechanism. Binding free energy analysis quantitatively confirms key interface residues and guide optimization. This study elucidates the conformation selection mechanism in APC-Asef inhibition and provides insights into peptide-based drug design.     

Determination of Trimethylamine N-oxide and Betaine in Serum and Food by Targeted Metabonomics

Trimethylamine N-oxide (TMAO), as a gut-derived metabolite, has been found to be associated with enhanced risk for atherosclerosis and cardiovascular disease. We presented a method for targeted profiling of TMAO and betaine in serum and food samples based on a combination of one-step sample pretreatment and proton nuclear magnetic resonance spectroscopy. The key step included a processing of sample preparation using a selective solid-phase extraction column for retention of basic metabolites. Proton signals at δ 3.29 and δ 3.28 were employed to quantify TMAO and betaine, respectively. The developed method was examined with acceptable linear relationship, precision, stability, repeatability, and accuracy. It was successfully applied to detect serum levels of TMAO and betaine in TMAO-fed mice and high-fructose-fed rats and also used to determine the contents of TMAO and betaine in several kinds of food, such as fish, pork, milk, and egg yolk.     

Boron group element doping of Li1.5Al0.5Ge1.5(PO4)3 based on microwave sintering

Journal of Solid State Electrochemistry - We report effectiveness of dopants selected from group 13, such as B, Ga, and In, on the conductivity of Li1.5Al0.5Ge1.5(PO4)3 (LAGP) that is recognized as...