PARADOXICAL EFFECT OF A GnRH AGONIST ON STEROIDOGENESIS IN CULTURED MONKEY GRANULOSA CELLS

In this study we demonstrate: (i) The GnRH agonist exerts a direct dose-dependet stimulative effect on the aromatase activity and progesterone production in cultured monkey granulosa cells; (ii)the stimulative effect on steroidogenesis can be completely blocked by concomitant treatment with a GnRH antagonist, suggesting that the actions of GnRH are mediated through stringent stereospecific recongnition sites; (iii) in addition to the stimulative effect, the GnRH agonist in the presence of gonadotropins also exerts an inhibitory effect, even though the peptide by itself is more effective in the stimulation of steroidogenesis, and the stimulation of gonadotropin on steroidogenesis could be gradually restored by decreasing the concentration of the GnRH agonist in the culture; and (iv) paradoxical effect can also be observed in the presence of cAMP-inducing agents, suggesting that the inhibitory action of the peptide on gonadotropin-induced steroidogenesis is localized at a step distal to the stringent reco     

Dirichlet型空间上的乘子

本文主要根据τ与μ的不同取值分三种情况刻划了Cn中单位球上Dirichlet 型空间上的点乘子空间M(Dτ,Dμ),并通过两个函数的构造表明:当τ≤n时,包含 关系M(Dτ)(?)Dτ和当τ>μ,τ>n-1时,包含关系M(Dτ)(?) M(Dμ)是严格的.     

激光标线的原理和实验

根据几何光学知识分析了激光标线原理.理论和实验表明:激光标线长度与激光光束形状、光学元件形状及材料折射率有关.并讨论了激光标线向两侧扩展的原因.     

一个数学建模问题的简单解法

银行利率给出了一个简单计算方法 ,这种方法更符合中学生思维的习惯 .     

上市公司高管薪酬和企业业绩关系研究

本运用我国生物医药上市公司的经验数据考察高管薪酬与企业业绩的关系问题。研究的结果表明高管薪酬水平与企业业绩显正相关，高管团队内的薪酬差距也与企业业绩显正相关，而高管持股则与企业业绩负相关，在统计上不显。因此章建议企业应该考虑股权激励的成本和效果，改善股权激励制度。研究还表明企业追求的目标是规模最大化而不是股东净资产收益率最大化。     

草酰胺分子构型、稳定性、IR光谱及分子轨道的密度泛函与从头算研究

运用多种密度泛函理论 (DFT)和从头算 (abinitio)方法研究了草酰胺顺、反异构体的分子几何构型 ,结果表明Beck88交换函数与LYP非局域相关函数形成杂化的DFT方法B3LYP与MP2方法计算结果比较吻合。在此基础上选择B3LYP方法对草酰胺分子电子结构、红外光谱和前线分子轨道组成进行了系统研究 ;与实验事实对比分析了气态草酰胺分子中配位原子的反应活性     

对分拆上市的分析与探讨

分析了分拆上市公司的益处 ,提出了做好分拆上市工作的建议 ,探讨了分拆上市对证券市场的影响     

Analyzing the effect of the inventory policy on order and inventory variability with linear control theory

In this paper we apply linear control theory to study the effect of various inventory policies on order and inventory variability, which are key drivers of supply chain performance. In particular, we study a two-echelon supply chain with a stationary demand pattern under the influence of three inventory policies: an inventory-on-hand policy that bases orders on the visible inventory at an installation, an installation-stock policy that bases orders on the inventory position (on-hand plus on-order inventory) at an installation, and an echelon-stock policy that bases orders on the inventory position at that installation and all downstream installations. We prove analytically that the inventory-on-hand policy is unstable in practical settings, confirming analytically what has been observed in experimental settings and in practice. We also prove that the installation-stock and echelon-stock policies are stable and analyze their effect on order and inventory fluctuation. Specifically, we show the general superiority of the echelon-stock in our setting and demonstrate analytically the effect of forecasting parameters on order and inventory fluctuations, confirming the results in other research.     

Banach空间中极大单调算子的一个邻近点算法

设E是Banach空间,T∶E→2E*是极大单调算子,T-10≠ф.令x0∈E,yn=(J λnT)-1xn en,xn 1=J-1(αnJxn (1-αn)Jyn),n0,λn>0,αn∈[0,1],文章研究了{xn}收敛性.     

混合方次的Waring——Goldbach问题

研究混合方次的Waring--Goldbach