二十二碳六烯酸乙酯对沙土鼠缺血再灌注脑损伤及水肿作用的研究

研究二十二碳六烯酸乙酯(E-DHA)对沙土鼠缺血再灌注脑损伤及其脑水肿的影响.选用雄性断奶沙土鼠灌胃给予二十二碳六烯酸乙酯(150 mg/(kg·d))或等体积溶媒10周,阻断沙土鼠双侧颈总动脉血流10 min,造成缺血再灌注模型;测定再灌注后脑组织中丙二醛(MDA)水平,还原型谷胱甘肽(GSH)含量,超歧化氧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)和钾、钠-ATP酶(Na ,K -ATPase)活性,脑水含量,钠、钾离子浓度及海马CA1区神经细胞存活百分数.结果表明:E-DHA预处理显著降低缺血再灌注沙土鼠脑组织MDA水平,阻止GSH含量、GSH-PX和Na ,K -ATPase活性下降,而对SOD的活性未表现出明显作用;E-DHA亦调节缺血再灌注沙土鼠脑组织钠、钾离子浓度,减轻缺血再灌注所致的脑水肿和神经细胞死亡.提示E-DHA对脑缺血再灌注脑损伤有显著保护作用,机制可能其与抗氧化作用有关.     

期权费用化小议

股票期权制度成为安然事件后会计界备受关注的一个新兴领域，本文通过对美国股票期权会计理论发展的分析．对我国股票期权制度在现阶段的实施提出了一些建议。     

陶瓷化学镀镍的研究

研究了陶瓷化学镀镍的实验操作方法、工艺条件及各种因素对镀层的影响,确定了陶瓷镀镍的最佳工艺方法及控制条件.     

Leaching behavior of V,Pb, Cd,Cr, and As from stone coal waste rock with different particle sizes

This paper investigates the leaching behavior of heavy metals (V, Pb, Cd, Cr, and As) from stone coal waste rocks with various particle sizes using dynamic leaching experiments. The results show that the dissolved concentrations of V and As initially increased and then slightly decreased as time progressed and that the dissolved concentrations of Pb, Cd, and Cr were high in the early stage before decreasing. The particle size of the stone coal waste rocks strongly influenced the heavy metal concentration in the leaching solutions. The effects of the particle size of the stone coal waste rocks on the dissolved concentrations of V, Pb, and As decreased in the order fine fraction > medium fraction > coarse fraction, and the effects of particle size on the dissolved concentrations of Cr and Cd decreased in the order medium fraction > coarse fraction > fine fraction and coarse fraction > medium fraction > fine fraction, respectively. The quantities of heavy metals dissolved from the stone coal waste rock with fine particle sizes were observed to decrease in the order V (17104.36 μg/kg) > As (609.41 μg/kg) > Pb (469.24 μg/kg) > Cr (56.35 μg/kg) > Cd (27.52 μg/kg), and the dissolution rates decreased in the order As (2.96%) > Pb (0.93%) > V (0.35%) > Cd (0.25%) > Cr (0.01%). The specific surface area, pore size of the stone coal waste rocks, and chemical forms of heavy metals also influenced the release of heavy metals from the stone coal waste rocks. Kinetic analysis showed that the dissolution of heavy metals fundamentally agreed with the rate equation controlled by the shrinking core model. The results of this study are expected to serve as a reference for the evaluation of heavy metals contamination from stone coal waste rocks.     

The hidden disintegration of cluster heterogeneity in Fe-based glass-forming alloy melt

The evolution of liquid metal at high temperature is known much less than their solid states. This is partially due to that the message concerning clusters, metastable phase or heterogeneity in liquid is usually too slight to be traced. Here, we shed some light on the nature of structural evolution of Fe-based glass-forming alloy during overheating process by the investigation of high-temperature melt viscometry and first principles simulations. It was found that a structural transition around 1400 ℃ occurred in the melts of initial homogeneous ingot, heterogeneous ingot and amorphous ribbons jointly, and was confirmed by the results from differential scanning calorimeter(DSC), and ab initio molecular dynamics(AIMD). Combining these results with Fe-Si-B ternary phase diagram and the melting characteristics of Fe-B compounds, it is safe to conclude that the disintegration of Fe_2B type clusters to Fe_3B-type clusters leads to the observed transition. These results offer a significant reference for the preparation and property control of Fe-based amorphous alloys.     

低轨道移动卫星信道中的DDPSK调制特性

针对低轨道卫星移动通信信道的大范围快速时变的多普勒频移特性,提出并分析了双差分相位调制方式（DDPSK）。结果证明,DDPSK与相关相位调制、差分相位调制相比,对于频率变化有很好的稳定性,能够克服大频偏对于移动通信的影响。并进一步给出了它在带遮蔽效应的莱斯信道的误码特性。     

基于软岩流变特性的边坡动态稳定性分析

以新疆华宏矿业北山露天煤矿边坡砂质泥岩为对象,对砂质泥岩弱层进行室内单轴压缩蠕变实验研究.采用西原体蠕变模型得到砂质泥岩的蠕变方程和松弛方程,结合Hoek-Brown准则反演了砂质泥岩弱层岩体的时变强度参数.应用FLAC3D有限差分模拟软件,对北山煤矿首采区非工作帮边坡进行动态稳定性分析.结果表明,由于砂质泥岩弱层强度参数随时间不断减小,边坡安全系数随之降低,历时18年左右,边坡安全系数从159逐渐降低到115,低于规范要求.研究结果为服务年限内矿山边坡动态安全预测提供了理论依据.     

高应变动力试桩拟合法误差来源分析

与传统的静荷载试验相比,高应变动力试桩拟合法是一种非常方便实用的分析技术,但该技术非常复杂,它的成功应用取决于诸多因素。通过剖析高应变动力试桩法的原理和拟合法的实质,结合工程实例,指出高应变动力试桩拟合法确定桩承载力不仅理论模型本身较静荷载试验存在差异,而且在数据处理过程中由于参数选择不同将引起承载力结果的误差。同时,人员素质也是准确应用该方法并给出合理结论的关键。高应变动力试桩拟合法误差来源的分析,对该法在实际应用过程中避免或减少可能产生的失误将是十分有益的。     

硫氰酸钠、钾与4′-溴-5′-硝基苯并-15-冠-5固体配合物的合成及性质

在丙酮溶液中合成了两种未见报道的 4′-溴-5′-硝基苯并-15-冠-5(L)与硫氰酸钠、钾的固体配合物.对它们进行了元素分析、红外光谱、紫外光谱、差热、热重和 X-射线粉末衍射分析及摩尔电导的测定.红外光谱等结果表明—NO_2、—Br 未参与配位,而 SCN~-则以 N 作为配位原子,故可推测配合物中心离子的配位数为6.K~+与L 并非生成常见的夹心配合物,而是生成1:1型非溶剂合、不含水的固体配合物.     

一类未知输入系统的降维观测器设计

在观测器匹配条件不满足的情况下, 针对一类线性时不变系统,探讨了一种降维观测器设计的问题.基于输出对未知输入相关度的概念,构造辅助输出,使得匹配条件得以满足.在假设辅助输出可测时提出了一种降维观测器的设计方法.实际上,辅助输出不完全可测,使用高增益观测器观测的辅助输出估计值代替辅助输出设计降维观测器.状态估计误差在特定的封闭球体内最终一致有界,通过改变观测器参数可以调节封闭球体的半径.对一个五阶系统设计降维观测器,仿真结果表明, 降维观测器和滑模观测器具有同样良好的观测效果.