稀有原人参二醇型皂苷的人肠道菌群生物转化

利用高分离度液相色谱-四极杆飞行时间质谱(RRLC-Q-TOF MS)和超高效液相色谱-三重四极杆质谱(UPLC-QQQ MS)定性定量分析了稀有原人参二醇型皂苷Rd, F₂, Rg₃, CK和Rh₂在离体人肠道菌群中的生物转化过程. 并将上述二醇型皂苷与人肠道菌群在体外厌氧, 37 ℃下共温孵育, 采用电喷雾质谱在负离子模式进行检测, 鉴定代谢产物, 监测其含量变化, 拟合代谢路径. 结果表明, 人参皂苷Rd主要被代谢为F₂, Rg₃, CK, Rh₂和PPD; 人参皂苷F₂主要被代谢为CK和PPD; 人参皂苷Rg₃主要被代谢为Rh₂和PPD; 人参皂苷CK和Rh₂主要被代谢为PPD. 在离体条件下, 人参皂苷Rd, F₂和Rg₃会被肠道菌群完全转化为其代谢产物, 而人参皂苷CK和Rh₂则不能被肠道菌群完全转化为其代谢产物. 原人参二醇型皂苷在人肠道菌群中的主要转化为脱糖基反应, 单糖苷和苷元是稀有原人参二醇型皂苷在人体内发挥药效的物质基础.     

LaCoO3对H2S选择氧化性能的影响

使用溶胶-凝胶法制备了LaCoO₃催化剂,采用XRD、BET和XPS等方式对催化剂进行了表征,考察了该催化剂制备过程中煅烧温度、表面活性剂PEG-6000和PEG-20000含量对其H₂S选择氧化制硫磺反应催化活性的影响。结果表明,表面活性剂PEG-6000及PEG-20000的添加能明显提高LaCoO₃的催化活性。0.02 mol La（NO₃）₃+0.02mol Co（NO₃）₂溶液中添加0.30 g PEG-20000、煅烧温度为650℃时所制备的LaCoO₃催化活性最好;在最佳反应温度260℃下,H₂S的转化率达到96.10%,硫选择性为93.77%。     

油浆高温快速裂解过程的气固相产物研究

采用高频炉快速热解装置研究油浆的高温快速热解特性,考察了热解温度、氮气流量对气固相产物的组成和产率的影响。温度是影响气相产物产率的关键因素,气相产物主要为甲烷、氢气和乙烯,升高温度可提高甲烷和氢气的产率,而乙烯产率受高温下二次反应的影响在800℃到达最大值后逐渐降低,乙烷、丙烯产率较小且受二次反应的影响在700℃到达最大值后逐渐降低,温度高于800℃时会有少量乙炔生成且升温可提高乙炔产率。增加氮气流量可降低甲烷、氢气分压,缩短乙烯、丙烯等在高温区的停留时间,从而增加气相产物的产率。积炭产率随热解温度升高迅速增加,氮气流量的增加能够削弱二次反应从而降低积炭产率。     

Quantitative Analysis of Main Components of Natural Gas Based on Raman Spectroscopy

Natural gas is composed of methane, ethane, propane, carbon dioxide, nitrogen, hydrogen, carbon monoxide and unknown alkane components of C4 or more (denoted as C4⁺) after desulfurization and dehydration treatment. The concentrations of the first seven components account for more than 90% of natural gas. When analyzing the natural gas composition using Raman spectral analysis methods, a small amount of unknown alkane components C4⁺ will have a negative impact on the analytical precision. In this work, a novel method that consists of an automatic decomposition algorithm of Raman spectra and a model for quantitative analysis was developed for the analysis of components of natural gas. The Raman spectrum of a natural gas sample could be decomposed into the sum of the Raman spectra of pure constituents and several Lorentz peaks by a nonlinear least-square optimization algorithm based on a linear additivity of Raman spectra. The concentration of the unknown alkane component C4⁺ was determined according to the area of the C-H deformation vibration peak which was common for most alkane molecules. Some training samples were used to establish the model between Raman characteristic peak areas and corresponding concentrations for each component. Compared with the existing Raman analysis methods, the new method solved the problem of analyzing natural gas containing unknown alkane components with good stability and accuracy. The experiments showed that the maximum absolute errors of this algorithm for methane, ethane, propane, carbon dioxide, nitrogen, hydrogen, and carbon monoxide respectively reached 0.57%, 0.37%, 0.21%, 0.07%, 0.18%, 0.04%, 0.13%, and the correlation coefficient to gas chromatographic results also reached 0.997, 0.986, 0.991, 0.998, 0.993, 1.000, 0.995, 0.982, respectively.     

Approach to 2′-(Dialkylamino)-1-alkyl-4′H-spiro[indoline-3,5′-oxazole]-2,4′-diones and 1,3-Oxazin-4-ones via Cyclization of Vilsmeier Salts withα-Hydroxy andβ-Carbonyl Amides

A straiglitforward and efficient synthetic method of 2′-(dialkylammo)-l-alkyl-4′H-spiro[indoline-3,5′-oxazole]-2,4′-diones and 2-(dialkylamino)-5,6-dihydro-4H-naphtho[2,1-e][1,3]oxazin-4-one-derivatives have been developed from a-hydroxy andβ-carbonyl amides and various Vilsmeier salts.A wide range of heterocyclic compounds were obtained in excellent yields(up to 97%),which will provide promising candidates lor chemical biology and drug discovery.     

Classical Communication Cost and Remote Preparation of Multi-qubit with Three-Party

We present a scheme for probabilistic remote preparation of multi-qubit with three-party from a sender to either of two receivers. The quantum channel is composed of a partial entangled tripartite GHZ state. We obtain the successful totM probability of the scheme in the general case and special case, respectively. We also calculate total classical communication cost required in the RSP process with three-party in the general case and special case, respectively.     

The cryogenic control system of BEPCⅡ

A superconducting cryogenic system has been designed and deployed in the Beijing Electron-Positron Collider Upgrade Project (BEPCⅡ). The system consists of a Siemens PLC (S7-PLC, Programmable Logic Controller) for the compressor control, an Allen Bradley (AB) PLC for the cryogenic equipments, and the Experimental Physics and Industrial Control System (EPICS) that integrates the PLCs. The system fully automates the superconducting cryogenic control with process control, PID (Proportional-Integral-Differential) control loops, real-time data access and data storage, alarm handler and human machine interface. It is capable of automatic recovery as well. This paper describes the BEPCⅡ cryogenic control system, data communication between S7-PLC and EPICS Input/Output Controllers (IOCs), and the integration of the flow control, the low level interlock, the AB-PLC, and EPICS.     

OTR渡越辐射束流测量中的CCD相机系统设计

本文针对OTR束流测量中用到的CCD相机系统,介绍了OTR束流测量的基本原理以及利用专用CCD芯片ICX208CL和AD9929在束测系统中关键部分相机系统设计中的应用,并对ICX208CL和AD9929进行了较为详细的介绍。     

Design and studies on the traveling wave transverse RF deflecting structure

With the development of free electron laser (FEL) and the international linear collider (ILC), the electron bunch length is getting smaller and smaller. The traveling-wave transverse RF deflecting structure is an important part of the RF deflecting method for bunch length measurement and phase space diagnostics. The operation mode in RF deflector is the ``TM₁₁-like' mode. Since the TM₁₁-like mode in this structure has a pair of degenerate dipole modes, two additional holes are provided on either side of each iris to stabilize the mode. The simulation and optimization have been done. A prototype has been fabricated and tested. The cold test results have been compared with the simulations of the first three modes.     

Study of closed orbit response to magnet vibrations at the SSRF storage ring

This paper presents the analytical and simulation responses of the closed orbit distortion in the SSRF storage ring to random and plane wave like magnet vibrations respectively. It is shown that the use of girder is very beneficial in the view of suppressing this response function. Effect of the independently supported gradient bending magnets to the closed orbit response is given. An analytic formula is written to give a rough estimate of the closed orbit distortion due to ground motion, taking into account the closed orbit response function and girder transfer function. As an example, the result of SSRF case is given.