大剂量多孔无针注射器结构优化

针对目前单孔无针注射器单次注射剂量小、需要多次重复注射的缺陷,提出一种大剂量多孔无针注射器.应用ANSYS Workbench仿真平台对多孔无针注射器的注射流场进行分析,发现多孔无针注射器的工作压力不低于13 MPa;并通过流固耦合分析,得到多孔无针注射器不同直径的应力变化规律,且拟合了不同压力下许用应力与最小安瓿直径之间的关系多项式.根据仿真结果设计正交试验对多孔无针注射器收缩段进行结构优化,得到优化方案：20°收缩角、1.4的长径比、2 mm的分布圆直径、4.05 mm的收缩段长度和0.165 mm的微孔直径.且通过安瓿的应力分析,验证了优化方案满足材料的力学性能要求.优化结果表明,该注射器具有比传统单孔注射器更大的注射剂量,可达5 mL,注射速度高达150 m/s以上,能击穿皮肤,同时又不致造成过多损伤.试验及动力学分析进一步验证了优化方案的可行性.     

Generalized Lagrangian Duality in Set-valued Vector Optimization via Abstract Subdifferential

In this paper, we investigate dual problems for nonconvex set-valued vector optimization via abstract subdifferential. We first introduce a generalized augmented Lagrangian function induced by a coupling vector-valued function for set-valued vector optimization problem and construct related set-valued dual map and dual optimization problem on the basic of weak efficiency, which used by the concepts of supremum and infimum of a set. We then establish the weak and strong duality results under this...     

A Comparative Study on the Failure Criteria for Predicting the Damage Initiation in Fiber-Reinforced Composites

Mechanics of Composite Materials - In this research, the maximum stress, Hashin, Puck, LaRC03, and Northwestern University (NU) criteria are analyzed based literature data, analytical results...     

Efficient Continuous Wave-laser emission of Pr3+-doped fluorides at room temperature

We report, to our knowledge for the first time, Continuous Wave (CW) laser emission at room temperature of Pr:LiYF₄ (Pr.YLF) at six wavelengths: 522, 545, 607, 639.5, 720 and 907.4 nm. The pump source was an argon-ion laser tuned to a wavelength of = 457.9 nm. The maximum output powers at 522 nm (³P_i ³H₅) and 639.5 nm (³P₀ ³F₂) were 144 and 266 mW, respectively. We also observed CW laser action of Pr:GdLiF₄ (Pr: GLF) at = 639 nm and of Pr:KYF₄ (Pr: KYF) at = 642.5 nm.     

侧喷射流的仿生鱼表面减阻优化研究

为了研究射流孔结构参数对水下射流减阻的影响,以金枪鱼为仿生对象建立仿生鱼模型,通过模拟鲨鱼鳃在仿生鱼模型侧面添加射流孔建立了射流模型.采用数值模拟方法,分析主流场速度及射流孔的形状、高度、位置、高宽比等单因素对仿生鱼表面减阻的影响规律.通过Design-expert软件对射流孔的结构参数进行响应面多目标参数优化,进一步分析了不同射流孔的结构参数在相互作用时对仿生鱼表面减阻的影响,最终确定了在距离鱼首5 mm处添加形状为后三角形,高度为6 mm,高宽比为4的射流孔时能够达到比较理想的减阻效果,此时模型的总阻力为2.510 21 N,相应的减阻率为6.49%.本文通过深入分析射流孔结构参数的影响,为水下射流减阻技术提供了重要的理论基础和实验指导,为仿生技术在水下流体力学领域的应用拓展了新的可能性.     

中国豹蛛属雾豹蛛组研究及一新种再记述(蜘蛛目:狼蛛科)

雾豹蛛组ＧｒｏｕｐＮｅｂｕｌｏｓａ是狼蛛科Ｌｙｃｏｓｉｄａｅ,豹蛛属Ｐａｒｄｏｓａ的分组．本文描述该组５种豹蛛,包括１新种记述,侧重在有鉴别价值的生殖器管,尤其是雄性生殖球的中突ｍｅ－ｄｉａｎａｐｏｐｈｙｓｉｓ．１．大别豹蛛Ｐ．ｄａｂｉｅｎｓｉｓＣｈａｉｅｔＹａｎｇｓｐ．ｎｏｖ．＊２．查普林豹蛛Ｐ．ｃｈａｐｉｎｉ（Ｆｏｘ,１９３５）,３．东方豹蛛Ｐ．ｏｒｉｅｎｓ（Ｃｈａｎｂｅｒｌｉｎ,１９２４）,４．苏门答腊豹蛛Ｐ．ｓｏｍａｔｒａｎａ（Ｔｈｅｒｅｌ,１８９２）,５．雾豹蛛Ｐ．ｎｅｂｕｌｏｓａ（Ｔｈｅｒｅｌ,１８７２）．     

Cycloaldol approach to the isobenzofuran core of eunicellin diterpenes

[reaction: see text] A novel cycloaldol approach to the isobenzofuran core common to many of the eunicellin diterpenes is described. The cycloaldol precursor was prepared by aldol addition of (S)-(+)-carvone and methacrolein followed by etherification to a glycolate ester. Chemoselective enolization of the glycolate ester led to the cycloaldol adduct in high yield and diastereoselectivity. An oxidative rearrangement-allylic diazene rearrangement sequence established the requisite cis ring fusion.     

Study of occupational health impact of atmospheric pollution on exposed workers at an iron and steel complex by using neutron activation analysis of scalp hair

The occupational health impact of atmospheric pollution on exposed workers at one iron and steel complex was studied by instrumental neutron activation analysis of workers' hair samples and medical examination. The experimental results indicate that there is a positive correlation between the high inhalation amounts of iron and other trace elements by the exposed workers and the symptom of their high blood pressure and hypoglycemia, which implies that the atmospheric environment polluted by iron and steel industry has an adverse health impact on the exposed workers. The measures to relieve and abate the occupational diseases caused by air-borne particulate matter should be taken     

Study on the immobilization of anti-IgG on Au-colloid modified gold electrode via potentiometric immunosensor, cyclic voltammetry, and electrochemical impedance techniques

The immobilization of anti-IgG on Au-colloid modified gold electrodes has been investigated. A cleaned gold electrode was first immersed in a mercaptoethylamine (AET) solution, and then gold nanoparticles were chemisorbed onto the thiol groups of the mercaptoethylamine. Finally, anti-IgG was adsorbed onto the surface of the gold nanoparticles. Potentiometric immunosensor, cyclic voltammetry, and electrochemical impedance techniques were used to investigate the immobilization of anti-IgG on Au colloids. In the impedance spectroscopic study, an obvious difference of the electron transfer resistance between the Au-colloid modified electrode and the bare gold electrode was observed. The cyclic voltammogram tends to be more irreversible with increased anti-IgG concentration. Using the potentiometric immunosensor, the proposed technique is based on that the specific agglutination of antibody-coated gold nanoparticles, averaging 16 nm in diameter, in the presence of the corresponding antigen causes a potential change that is monitored by a potentiometry. It is found that the developed immunoagglutination assay system is sensitive to the concentration of IgG antigen as low as 12 ng mL(-1). Experimental results showed that the developed technique is in satisfactory agreement with the ELISA method, and that gold nanoparticles can be used as a biocompatible matrix for antibody or antigen immobilization.