浅谈钻孔灌注桩的施工质量控制措施

桩基作为工程建设中涉及到结构安全的重要组成部分,基础的质量是尤其受到重视和严格要求的;而钻孔灌注桩因为它自身使用范围广、成本适中、噪音小等优点在公路桥梁建设中被广泛使用;但是施工中也常常存在一些缺陷和问题,本文将主要从质量控制的角度来具体分析和解释:钻孔灌注桩在施工过程中的控制措施。     

Effect of Media on the in vitro Degradation of Biodegradable Ureteral Stent

The biodegradable ureteral stent should retain their supporting properties for defined period and then gradually degrade to small particles with the flow of urine. The mechanism and process of the stent’s degradation should be investigated and understood well due to its direct impact on the stents’ usage. An enhanced braidbased degradable ureteral stent composed of poly-glycolic acid(PGA) and the copolymer of lactic and glycolic acid(PGLA) was evaluated in vitro in this study with four kinds of degradable media:human urine(HU,pH = 7. 4),artificial urine(AU,pH = 5. 8),and phosphate buffer solutions( PBS,pH = 5. 8 and 7. 4) so as to compare the effects of media on the degradation of stents. The mechanical properties and morphology were observed at different degradaing time intervals of 0,7,14,21,28,and 35 d. The in vitro degradation behaviors of stents in four kinds of media were extremely different. The degradation rate of stents in HU was the highest. The impact of media’s pH to the degradation is not obvious while the components in the media contribute much to the difference.     

3D肿瘤支架的研究进展及其在药物筛选中的应用

3D肿瘤支架作为新兴的肿瘤细胞培养平台,能够重现肿瘤组织的3D结构,提供仿生微环境和降低肿瘤细胞的药物敏感性,在肿瘤生理学研究和肿瘤耐药机制研究中具有独特优势。综述了3D肿瘤支架的类型及其优缺点,从模拟肿瘤-间质细胞相互作用和肿瘤内部梯度缺氧环境两方面介绍了3D肿瘤支架模拟肿瘤微环境的研究进展,并对3D肿瘤支架在药物筛选中的应用进行分析。揭示了肿瘤支架在研究肿瘤耐药性机制、开发新型抗肿瘤药物,以及作为个性化肿瘤治疗临床前平台中的重要作用。最后对肿瘤支架的构建和应用提出设想和展望,旨在为构建高仿真肿瘤模型,研究肿瘤的异质性和肿瘤治疗方法提供参考。     

Entropy Corrections to Three-Dimensional Black Holes and de Sitter Spaces

It has been shown that non-rotating black holes Recently study showed that thermal fluctuations would give in three or four dimensions possess a canonical entropy. rise to logarithmic corrections to Bekenstein Hawking entropy in area with a model-dependent uncertain coefficient. In this paper, the thermal fluctuations on Bekenstein-Hawking entropy in three-dimensional AdS black holes, Schwarzschild-de Sitter space and Kerr-de Sitter （KdS） spacetime with J = 0 will be considered based on a uniformly spaced area spectrum approach. Our conclusion shows that there is the same correction form in all cases we considered.