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91.
Quantum networks are distributed many-body quantum systems with tailored topology and controlled information exchange. We present two schemes to generate remote entanglement, in atomic external degrees of freedom and between cavities. In the first scheme, we entangle two atoms with their cavities in momentum space through Bragg diffraction. Thereafter, in order to trace out the cavities, we let resonantly interact an auxiliary atom with each cavity. In the last, we perform quantum measurement on two auxiliary atoms and get remote entangled state in atomic external degrees of freedom. In the second scheme, we have a three cavities system. The other two cavities, A and B, are entangled with indistinguishable modes of cavity, C. Performing quantum measurement on third cavity, C, we disentangle it from the system and the cavities, A and B, become entangled.  相似文献   
92.
Zeynel Abidin Ozdemir 《Physica A》2009,388(12):2461-2468
This paper aims to analyze the linkages between international stock markets and to search for an optimum model for analyzing their interactions taking into consideration their geographical location, using the vector fractionally integrated autoregressive moving-average (VARFIMA) model. This model has not so far been employed in examining the interdependence among the stock markets of Germany, Japan, the UK, and the USA. The results of the paper show that there is an interconnection among the stock markets of these countries.  相似文献   
93.
94.
Candida rugosa lipase was modified via reductive alkylation to increase its hydrophobicity to work better in organic solvents. The free amino group of lysines was alkylated using propionaldehyde with different degrees of modification obtained (49 and 86%). Far-ultraviolet circular dichroism (CD) spectroscopy of the lipase in aqueous solvent showed that such chemical modifications at the enzyme surface caused a loss in secondary and tertiary structure that is attributed to the enzyme unfolding. Using molecular modeling, we propose that in an aqueous environment the loss in protein structure of the modified lipase is owing to disruption of stabilizing salt bridges, particularly of surface lysines. Indeed, molecular modeling and simulation of a salt bridge formed by Lys-75 to Asp-79, in a nonpolar environment, suggests the adoption of a more flexible alkylated lysine that may explain higher lipase activity in organic solvents on alkylation.  相似文献   
95.
Journal of Thermal Analysis and Calorimetry - A hybrid nanofluid phenomenon is considered involving nanoparticles since such particles are potential medication transportation devices in biomedical...  相似文献   
96.
Stir-bar-sorptive extraction followed by liquid desorption and large-volume injection capillary gas chromatography with mass spectrometric detection (SBSE–LD–LVI-GC–MS), had been applied for the determination of ultra-traces of eight pyrethroid pesticides (acrinathrin, cypermethrin, deltamethrin, esfenvalerate, fenpropathrin, fenvalerate, and permethrin cis and trans isomers) in water samples. Instrumental calibration for selected-ion monitoring acquisition and conditions that could affect the SBSE–LD efficiency are fully discussed. By performing systematic assays on 30-mL water samples spiked at the 0.10 g L–1 level it was established that stir-bars coated with 47 L polydimethylsiloxane, an equilibrium time of 60 min (750 rpm), 5% methanol as organic modifier, and acetonitrile as back-extraction solvent, provided the best analytical performance to monitor pyrethroid pesticides in water matrices. Good accuracy (81.8–105.0%) and remarkable reproducibility (<11.7%) were obtained, and the experimental recovery data were in good agreement with the theoretical equilibrium described by octanol–water partition coefficients (log KO/W), with the exception of acrinathrin for which lower yields were measured. Excellent linear dynamic ranges between 25 and 400 ng L–1 (r2>0.994), low quantification (3.0–7.5 ng L–1) and detection (1.0–2.5 ng L–1) limits were also achieved for the eight pyrethroid pesticides studied. The method was successfully used for analysis of tapwater and groundwater matrices spiked at the 0.10 g L–1, revealing the suitability of the method for determination of pyrethroid pesticides in real samples. The method was shown be reliable and sensitive and a small volume of sample was required to monitor pyrethroids at ultra-trace levels, in compliance with international regulatory directives on water quality.  相似文献   
97.
    
Extracellular signal-regulated kinases 1 and 2 (ERK1/2) play key roles in promoting cell survival and proliferation through the phosphorylation of various substrates. Remarkable antitumour activity is found in many inhibitors that act upstream of the ERK pathway. However, drug-resistant tumour cells invariably emerge after their use due to the reactivation of ERK1/2 signalling. ERK1/2 inhibitors have shown clinical efficacy as a therapeutic strategy for the treatment of tumours with mitogen-activated protein kinase (MAPK) upstream target mutations. These inhibitors may be used as a possible strategy to overcome acquired resistance to MAPK inhibitors. Here, we report a class of repeat proteins—designed ankyrin repeat protein (DARPin) macromolecules targeting ERK2 as inhibitors. The structural basis of ERK2–DARPin interactions based on molecular dynamics (MD) simulations was studied. The information was then used to predict stabilizing mutations employing a web-based algorithm, MAESTRO. To evaluate whether these design strategies were successfully deployed, we performed all-atom, explicit-solvent molecular dynamics (MD) simulations. Two mutations, Ala → Asp and Ser → Leu, were found to perform better than the original sequence (DARPin E40) based on the associated energy and key residues involved in protein-protein interaction. MD simulations and analysis of the data obtained on these mutations supported our predictions.  相似文献   
98.
    
The commercial value of cashew nut shell liquid (CNSL) has become a cornerstone of the agrowaste industry. It is the by‐product of the cashew industry and has an 1/8 inch thickness of soft honeycomb structure. CNSL contains phenolic lipids with aliphatic chains such as anacardic acid, cardanol, cardol and methyl cardol, and their derivatives. The developed GC–MS method is rapid, accurate and selective using a selected derivatizing reagent, namely N‐methyl‐N‐(trimethylsilyl)‐trifluoroacetamide that was previously diluted 1:1% with anhydrous pyridine. The proposed GC–MS method was applied for the analysis of different CNSL samples. The results showed that all classes of CNSL compounds were detected. The four alkyl phenols were detected with their different alkyl sidechains without any interference. This method is also specified for the detection of fatty acids of saturated and unsaturated chains. Silylation did not cause any alteration in the chemical structure of CNSL compounds regardless of esterification action. Silylation is considered a safe derivatizing agent compatible with GC chromatography and specific for all volatile and nonvolatile polar and nonpolar CNSL compounds that could be detected in CNSL samples.  相似文献   
99.
The Steiner multi-ring network design problem with revenues consists of designing node-disjoint multiple rings connected by a specific node (hub) and passing through all the nodes with high priority of service and some of the nodes with low priority of service. The number of nodes in each ring has an upper bound to assure a certain level of service. Besides the usual arc link costs, we also consider revenues between each pair of nodes in the same ring, even when they are not connected by a direct link. The objective is to minimize the difference between the total connection cost and total revenue. The problem is a generalization of the problem studied in Gouveia and Pires (Eur J Oper Res 133:21–31, 2001a) and it can also be seen as a combination of variants of two NP-Hard problems, the vehicle routing problem and the maximum edge-weighted clique problem. We introduce and discuss two types of integer linear programming formulations and propose some valid inequalities to strengthen the linear programming relaxation. Computational results are presented to evaluate the quality of the linear programming relaxation bounds associated with these formulations as well as efficiency of the models to obtain the optimal integer solutions.  相似文献   
100.
Nekrasov-Okounkov identity gives a product representation of the sum over partitions of a certain function of partition hook length. In this paper, we give several generalizations of the Nekrasov-Okounkov identity using the cyclic symmetry of the topological vertex.  相似文献   
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